Basic Information:

  VIRBase ID:  

HHID00066241

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-26a-2-3p:  MIMAT0004681          CPSF3:  NM_001321834     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-26a-2-3p	CPSF3
miRBase Accession/Entrez ID	MIMAT0004681	51692
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CPSF-73//CPSF73

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-26a-2-3p	rs1158238029 chr12:57824632    C/G rs1386005710 chr12:57824636    A/G rs1386005710 chr12:57824636    A/T rs768371795 chr12:57824638    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CPSF3	chr2:9605498(+) A-I      intronic chr2:9605501(+) A-I      intronic chr2:9605514(+) A-I      intronic chr2:9610301(+) A-I      intronic chr2:9610333(+) A-I      intronic chr2:9610338(+) A-I      intronic chr2:9610237(+) A-I      intronic chr2:9611088(+) A-I      intronic chr2:9604746(+) A-I      intronic chr2:9604764(+) A-I      intronic chr2:9605462(+) A-I      intronic chr2:9605488(+) A-I      intronic chr2:9587448(+) A-I      intronic chr2:9588869(+) A-I      intronic chr2:9588960(+) A-I      intronic chr2:9590481(+) A-I      intronic chr2:9590486(+) A-I      intronic chr2:9590493(+) A-I      intronic chr2:9591711(+) A-I      intronic chr2:9605507(+) A-I      intronic chr2:9591716(+) A-I      intronic chr2:9591939(+) A-I      intronic chr2:9592390(+) A-I      intronic chr2:9611264(+) A-I      intronic chr2:9595539(+) A-I      intronic chr2:9598119(+) A-I      intronic chr2:9598120(+) A-I      intronic chr2:9598374(+) A-I      intronic chr2:9584358(+) A-I      intronic chr2:9611292(+) A-I      intronic chr2:9611193(+) A-I      intronic chr2:9611189(+) A-I      intronic chr2:9611141(+) A-I      intronic chr2:9610321(+) A-I      intronic chr2:9608966(+) A-I      intronic chr2:9608874(+) A-I      intronic chr2:9608856(+) A-I      intronic chr2:9598375(+) A-I      intronic chr2:9598386(+) A-I      intronic chr2:9598390(+) A-I      intronic chr2:9584357(+) A-I      intronic chr2:9599120(+) A-I      intronic chr2:9599121(+) A-I      intronic chr2:9583274(+) A-I      intronic chr2:9600054(+) A-I      intronic chr2:9600341(+) A-I      intronic chr2:9600373(+) A-I      intronic chr2:9600397(+) A-I      intronic chr2:9600407(+) A-I      intronic chr2:9600411(+) A-I      intronic chr2:9600419(+) A-I      intronic chr2:9600443(+) A-I      intronic chr2:9600513(+) A-I      intronic chr2:9582793(+) A-I      intronic chr2:9604795(+) A-I      intronic chr2:9602030(+) A-I      intronic chr2:9574345(+) A-I      intronic chr2:9574356(+) A-I      intronic chr2:9574447(+) A-I      intronic chr2:9574453(+) A-I      intronic chr2:9601591(+) A-I      intronic chr2:9584454(+) A-I      intronic chr2:9584442(+) A-I      intronic chr2:9584361(+) A-I      intronic chr2:9601555(+) A-I      intronic chr2:9608825(+) A-I      intronic chr2:9608615(+) A-I      intronic chr2:9577490(+) A-I      intronic chr2:9577537(+) A-I      intronic chr2:9608412(+) A-I      intronic chr2:9608360(+) A-I      intronic chr2:9599936(+) A-I      intronic chr2:9588866(+) A-I      intronic chr2:9604754(+) A-I      intronic chr2:9590220(+) A-I      intronic chr2:9611087(+) A-I      intronic chr2:9599193(+) A-I      intronic chr2:9600829(+) A-I      intronic chr2:9608617(+) A-I      intronic chr2:9611288(+) A-I      intronic chr2:9590796(+) A-I      intronic chr2:9608481(+) A-I      intronic chr2:9602074(+) A-I      intronic chr2:9611222(+) A-I      intronic chr2:9590244(+) A-I      intronic chr2:9575612(+) A-I      intronic chr2:9608574(+) A-I      intronic chr2:9611235(+) A-I      intronic chr2:9574328(+) A-I      intronic chr2:9601537(+) A-I      intronic chr2:9604800(+) A-I      intronic chr2:9605439(+) A-I      intronic chr2:9601711(+) A-I      intronic chr2:9612869(+) A-I      intronic chr2:9588958(+) A-I      intronic chr2:9610241(+) A-I      intronic chr2:9592338(+) A-I      intronic chr2:9592049(+) A-I      intronic chr2:9601648(+) A-I      intronic chr2:9576717(+) A-I      intronic chr2:9587345(+) A-I      intronic chr2:9595398(+) A-I      intronic chr2:9579425(+) A-I      intronic chr2:9610334(+) A-I      intronic chr2:9604820(+) A-I      intronic chr2:9608855(+) A-I      intronic chr2:9611293(+) A-I      intronic chr2:9610128(+) A-I      intronic chr2:9598429(+) A-I      intronic chr2:9608384(+) A-I      intronic chr2:9608616(+) A-I      intronic chr2:9612014(+) A-I      intronic chr2:9606587(+) A-I      intronic chr2:9592030(+) A-I      intronic chr2:9608365(+) A-I      intronic chr2:9605480(+) A-I      intronic chr2:9592302(+) A-I      intronic chr2:9606615(+) A-I      intronic chr2:9599191(+) A-I      intronic chr2:9609029(+) A-I      intronic chr2:9610105(+) A-I      intronic chr2:9605522(+) A-I      intronic chr2:9594416(+) A-I      intronic chr2:9606275(+) A-I      intronic chr2:9601709(+) A-I      intronic chr2:9589398(+) A-I      intronic chr2:9593753(+) A-I      intronic chr2:9589250(+) A-I      intronic chr2:9598064(+) A-I      intronic chr2:9587422(+) A-I      intronic chr2:9587694(+) A-I      intronic chr2:9598448(+) A-I      intronic chr2:9606664(+) A-I      intronic chr2:9611094(+) A-I      intronic chr2:9610201(+) A-I      intronic chr2:9605506(+) A-I      intronic chr2:9598087(+) A-I      intronic chr2:9608453(+) A-I      intronic chr2:9611223(+) A-I      intronic chr2:9610142(+) A-I      intronic chr2:9599904(+) A-I      intronic chr2:9590410(+) A-I      intronic chr2:9610231(+) A-I      intronic chr2:9611142(+) A-I      intronic chr2:9600051(+) A-I      intronic chr2:9609017(+) A-I      intronic chr2:9610088(+) A-I      intronic chr2:9612846(+) A-I      intronic chr2:9588825(+) A-I      intronic chr2:9592337(+) A-I      intronic chr2:9608940(+) A-I      intronic chr2:9579424(+) A-I      intronic chr2:9608589(+) A-I      intronic chr2:9605512(+) A-I      intronic chr2:9592370(+) A-I      intronic chr2:9610232(+) A-I      intronic chr2:9601530(+) A-I      intronic chr2:9599809(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CPSF3	chr2:9579424(+) A-G intron -    22484847 chr2:9579425(+) A-G intron -    22484847 chr2:9588825(+) A-G intron -    22484847 chr2:9590220(+) A-G intron -    22484847 chr2:9590410(+) A-G intron -    22484847 chr2:9590420(+) A-G intron -    22484847 chr2:9592030(+) A-G intron -    22484847 chr2:9592049(+) A-G intron -    22484847 chr2:9594416(+) A-G intron -    22484847 chr2:9595398(+) A-G intron -    22484847 chr2:9598087(+) A-G intron -    22484847 chr2:9599191(+) A-G intron -    22484847 chr2:9599193(+) A-G intron -    22484847 chr2:9599878(+) A-G intron -    22484847 chr2:9600829(+) A-G intron -    22484847 chr2:9601530(+) A-G intron -    22484847 chr2:9601537(+) A-G intron -    22484847 chr2:9601648(+) A-G intron -    22484847 chr2:9601652(+) A-G intron -    22484847 chr2:9601711(+) A-G intron -    22484847 chr2:9602074(+) A-G intron -    22484847 chr2:9605480(+) A-G intron -    22484847 chr2:9605506(+) A-G intron -    22484847 chr2:9605512(+) A-G intron -    22484847 chr2:9605522(+) A-G intron -    22484847 chr2:9608495(+) A-G intron -    22484847 chr2:9610088(+) A-G intron -    22484847 chr2:9610232(+) A-G intron -    22484847 chr2:9610241(+) A-G intron -    22484847 chr2:9610334(+) A-G intron -    22484847 chr2:9611222(+) A-G intron -    22484847 chr2:9611223(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CPSF3	chr2:9572673-9572674(+) m6A CDS       - chr2:9572695-9572696(+) m6A CDS       - chr2:9572706-9572707(+) m6A CDS       - chr2:9588358-9588359(+) Cm CDS//exon       - chr2:9588453-9588454(+) m6A CDS//exon       26404942 chr2:9588469-9588470(+) m6A CDS//exon       26404942 chr2:9593060-9593061(+) m6A CDS       26404942 chr2:9593067-9593068(+) m6A CDS       26404942 chr2:9593073-9593074(+) m6A CDS       26404942 chr2:9607936-9607937(+) m6A exon//intron       27773535 chr2:9608063-9608064(+) m6A exon//intron       - chr2:9611473-9611474(+) m6A CDS//exon       - chr2:9611488-9611489(+) m6A CDS//exon       - chr2:9611541-9611542(+) m6A CDS//exon       - chr2:9611562-9611563(+) m6A CDS//exon       27773535 chr2:9613115-9613116(+) m6A CDS//exon       24981863//27773535 chr2:9613147-9613148(+) m6A 3'UTR//exon       24981863//27773535//22608085 chr2:9613164-9613165(+) m6A 3'UTR//exon       24981863//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-26a-2-3p	Exosome Plasma     23663360 Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326 Exosome Breast milk     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	CPSF3	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-26a-2-3p
Interactor2: CPSF3

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.