Detail Information

Basic Information:


  VIRBase ID:  

HHID00065984

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-138-1-3p:           KHSRP:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-138-1-3p KHSRP
miRBase
Accession/Entrez ID		 MIMAT0004607 8570
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - FBP2//FUBP2//KSRP//p75

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-138-1-3p
rs1215016527 chr3:44114288    C/T
rs759234321 chr3:44114292    G/A
rs759234321 chr3:44114292    G/C
rs770499543 chr3:44114276    T/C
rs773680447 chr3:44114278    C/A
rs892673276 chr3:44114281    C/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase KHSRP
chr19:6413362-6413363(-) m6A 3'UTR       27773535
chr19:6413436-6413437(-) m6A 3'UTR       24284625//25456834//28052920//27773535
chr19:6413447-6413448(-) m6A 3'UTR       24284625//25456834//28052920//27773535
chr19:6413454-6413455(-) m6A 3'UTR       24284625//25456834//24981863//28052920//27773535
chr19:6413495-6413496(-) m6A 3'UTR//CDS       24284625//25456834//24981863//27773535
chr19:6413581-6413582(-) m6A 3'UTR//CDS//intron       24284625//24209618//24981863//27773535
chr19:6413601-6413602(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535
chr19:6413612-6413613(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535
chr19:6413673-6413674(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535
chr19:6413739-6413740(-) m6A 3'UTR//intron       24981863//27773535
chr19:6413802-6413803(-) m6A 3'UTR//intron       24981863//27773535
chr19:6413821-6413822(-) m6A 3'UTR//intron       24981863//27773535
chr19:6413836-6413837(-) m6A 3'UTR//intron       24981863//27773535
chr19:6414106-6414107(-) m6A 3'UTR//intron       24284625//24209618
chr19:6414480-6414481(-) m6A 3'UTR//intron       24284625//24209618//22575960
chr19:6414526-6414527(-) Am 3'UTR//intron       -
chr19:6414631-6414632(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//27371828//27773536//22575960//22608085
chr19:6414693-6414694(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr19:6414831-6414832(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr19:6414858-6414859(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr19:6414866-6414867(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr19:6414879-6414880(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr19:6415062-6415063(-) m6A CDS//intron       24284625//24209618//25456834//27371828//27773536//22575960//22608085
chr19:6415160-6415161(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960
chr19:6415208-6415209(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960
chr19:6415229-6415230(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960
chr19:6415260-6415261(-) m6A CDS//exon//intron       24284625//24209618//24981863//28052920//27773535//27371828//22575960
chr19:6415428-6415429(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//27371828//22575960
chr19:6415582-6415583(-) m6A CDS//exon//intron       24284625//24209618//24981863//28052920//27773535
chr19:6415720-6415721(-) m6A CDS//exon       24284625//24209618//22575960
chr19:6416397-6416398(-) m6A CDS       24284625//27773535//22575960
chr19:6416582-6416583(-) m6A CDS       27773535
chr19:6416636-6416637(-) m6A CDS       27773535//27773536
chr19:6417049-6417050(-) m6A CDS       24284625//24981863//26404942//27773535//27773536//22575960
chr19:6417089-6417090(-) m6A CDS       24284625//24981863//26404942//27773535//22575960
chr19:6418031-6418032(-) m6A CDS//exon       24284625//24981863//27773535//22575960
chr19:6418067-6418068(-) m6A CDS//exon       24284625//27773535//22575960
chr19:6418533-6418534(-) m6A CDS//exon       24284625//27773535//22575960
chr19:6418729-6418730(-) m6A CDS//exon       24284625//22575960
chr19:6418829-6418830(-) m6A CDS//exon       24284625//22575960
chr19:6420135-6420136(-) m6A CDS//exon//intron       26404942//22575960
chr19:6421015-6421016(-) m6A exon//intron       22575960
chr19:6421308-6421309(-) m6A 5'UTR//CDS//exon       -
chr19:6421427-6421428(-) m6A exon//intron       -
chr19:6421662-6421663(-) m6A 5'UTR//CDS//exon       -
chr19:6422352-6422353(-) Gm 5'UTR//CDS//exon       -
chr19:6422366-6422367(-) m6A 5'UTR//CDS//exon       27371828//22575960
chr19:6424159-6424160(-) m6A 5'UTR//intron       24284625//24209618//27371828//22575960
chr19:6424187-6424188(-) m6A 5'UTR//intron       24284625//24209618//27371828//22575960
chr19:6424596-6424597(-) m6A CDS       24209618//27371828//27773536
chr19:6424688-6424689(-) m6A CDS       24209618//24981863//27371828//27773536
chr19:6424704-6424705(-) m6A CDS       24209618//24981863//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-138-1-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
KHSRP
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)|K562 cells     -
Membrane HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-138-1-3p
Interactor2: KHSRP

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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