Basic Information:

  VIRBase ID:  

HHID00065981

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-138-1-3p:  MIMAT0004607          H3-3B:  NM_005324     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-138-1-3p	H3-3B
miRBase Accession/Entrez ID	MIMAT0004607	3021
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	H3-3A//H3.3B//H3F3B

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-138-1-3p	rs1215016527 chr3:44114288    C/T rs759234321 chr3:44114292    G/A rs759234321 chr3:44114292    G/C rs770499543 chr3:44114276    T/C rs773680447 chr3:44114278    C/A rs892673276 chr3:44114281    C/T

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-138-1-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	H3-3B	Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-138-1-3p
Interactor2: H3-3B

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.