Detail Information

Basic Information:


  VIRBase ID:  

HHID00065956

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-143-5p:           SLC36A1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-143-5p SLC36A1
miRBase
Accession/Entrez ID
MIMAT0004599 206358
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - Dct1//LYAAT1//PAT1//TRAMD3

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-143-5p
rs1240622815 chr5:149428959    C/T
rs1379718357 chr5:149428964    G/A
rs747639742 chr5:149428962    T/C
rs1440810125 chr5:149428950    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SLC36A1
chr5:150847734(+) A-I      intronic
chr5:150834413(+) A-I      intronic
chr5:150834403(+) A-I      intronic
chr5:150834391(+) A-I      intronic
chr5:150830848(+) A-I      intronic
chr5:150832602(+) A-I      intronic
chr5:150868835(+) A-I      3'UTR
chr5:150832221(+) A-I      intronic
chr5:150834458(+) A-I      intronic
chr5:150832622(+) A-I      intronic
chr5:150834439(+) A-I      intronic
chr5:150832201(+) A-I      intronic
chr5:150830852(+) A-I      intronic
chr5:150832189(+) A-I      intronic
chr5:150834449(+) A-I      intronic
chr5:150832311(+) A-I      intronic
chr5:150837671(+) A-I      intronic
chr5:150832598(+) A-I      intronic
chr5:150837592(+) A-I      intronic
chr5:150832310(+) A-I      intronic
chr5:150832174(+) A-I      intronic
chr5:150837609(+) A-I      intronic
chr5:150835805(+) A-I      intronic
chr5:150862417(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SLC36A1
chr5:150832310(+) A-G intron -    22484847
chr5:150832311(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SLC36A1
chr5:150816713-150816714(+) m6A 5'UTR       24981863
chr5:150827219-150827220(+) m6A 5'UTR//intron       24981863
chr5:150827275-150827276(+) m6A 5'UTR//intron       24981863
chr5:150827335-150827336(+) m6A 5'UTR//intron       -
chr5:150859014-150859015(+) m6A 3'UTR//CDS       24284625
chr5:150867737-150867738(+) m6A 3'UTR//CDS       24981863
chr5:150868063-150868064(+) m6A 3'UTR       24981863
chr5:150868544-150868545(+) m6A 3'UTR       24981863
chr5:150868590-150868591(+) m6A 3'UTR       24981863
chr5:150868667-150868668(+) m6A 3'UTR       25456834//24981863//22608085
chr5:150868763-150868764(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr5:150868773-150868774(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr5:150868995-150868996(+) m6A 3'UTR       24284625//24209618//24981863//22608085
chr5:150869065-150869066(+) m6A 3'UTR       24284625//24209618//24981863//22608085
chr5:150869101-150869102(+) m6A 3'UTR       24284625//24981863//22608085
chr5:150869113-150869114(+) m6A 3'UTR       24284625//24981863//22608085
chr5:150869122-150869123(+) m6A 3'UTR       24284625//24981863//22608085
chr5:150869175-150869176(+) m6A 3'UTR       24981863//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-143-5p
Exosome Breast milk     22211110
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
SLC36A1
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-143-5p
Interactor2: SLC36A1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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