Detail Information

Basic Information:


  VIRBase ID:  

HHID00065932

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-143-5p:           LINS1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-143-5p LINS1
miRBase
Accession/Entrez ID		 MIMAT0004599 55180
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - LINS//MRT27//WINS1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-143-5p
rs1240622815 chr5:149428959    C/T
rs1379718357 chr5:149428964    G/A
rs747639742 chr5:149428962    T/C
rs1440810125 chr5:149428950    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR LINS1
chr15:101127245(-) A-I      intronic
chr15:101142245(-) A-I      intronic
chr15:101109073(-) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase LINS1
chr15:101099624-101099625(-) m6A 3'UTR       24981863//22608085
chr15:101104915-101104916(-) m6A 3'UTR       24981863//22608085
chr15:101104935-101104936(-) m6A 3'UTR       22608085
chr15:101104945-101104946(-) m6A 3'UTR       22608085
chr15:101108378-101108379(-) m6A 3'UTR//intron       27773535
chr15:101108514-101108515(-) m6A 3'UTR//intron       24981863//22608085
chr15:101108556-101108557(-) m6A 3'UTR//intron       24981863//22608085
chr15:101108602-101108603(-) m6A 3'UTR//intron       24981863//22608085
chr15:101108608-101108609(-) m6A 3'UTR//intron       24981863//22608085
chr15:101108622-101108623(-) m6A 3'UTR//intron       24981863//22608085
chr15:101108983-101108984(-) m6A 3'UTR//intron       22608085
chr15:101109035-101109036(-) m6A 3'UTR//intron       22608085
chr15:101109440-101109441(-) m6A 3'UTR//exon//intron       24981863//27773535//22608085
chr15:101109452-101109453(-) m6A CDS//exon//intron       24981863//27773535//22608085
chr15:101109459-101109460(-) m6A CDS//exon//intron       24981863//27773535//22608085
chr15:101109562-101109563(-) m6A CDS//exon//intron       24981863//27773535//22608085
chr15:101109720-101109721(-) m6A CDS//exon//intron       24284625//24209618//24981863//26404942//27773535//22608085
chr15:101109772-101109773(-) m6A CDS//exon//intron       24981863//27773535//22608085
chr15:101109919-101109920(-) m6A CDS//exon//intron       24284625//27773535//22608085
chr15:101110002-101110003(-) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22575960//22608085
chr15:101110019-101110020(-) m6A CDS//exon//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr15:101110115-101110116(-) m6A CDS//exon//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr15:101110164-101110165(-) m6A CDS//exon//intron       24981863//27773535//22608085
chr15:101110274-101110275(-) m6A CDS//exon//intron       24209618//24981863
chr15:101110571-101110572(-) m6A exon//intron       24981863
chr15:101113961-101113962(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr15:101114003-101114004(-) m6A CDS//exon       24284625//24981863//22608085
chr15:101114023-101114024(-) m6A CDS//exon       24284625//24981863//22608085
chr15:101114079-101114080(-) m6A CDS//exon       24284625//24209618//24981863//22608085
chr15:101114097-101114098(-) m6A CDS//exon       24284625//24209618//24981863//22608085
chr15:101114136-101114137(-) m6A CDS//exon       24284625//24981863//22608085
chr15:101114240-101114241(-) m6A CDS//exon       24981863//22608085
chr15:101114337-101114338(-) m6A CDS//exon       24981863
chr15:101121135-101121136(-) m6A 5'UTR//exon//intron       24981863
chr15:101126464-101126465(-) m6A 5'UTR//intron       24981863
chr15:101126490-101126491(-) m6A 5'UTR//intron       24981863
chr15:101126515-101126516(-) m6A 5'UTR//intron       24981863
chr15:101142401-101142402(-) m6A 5'UTR//intron       24981863
chr15:101142727-101142728(-) m6A exon       24981863
chr15:101142784-101142785(-) m6A exon       24981863
chr15:101142863-101142864(-) m6A exon       24981863
chr15:101142934-101142935(-) m6A exon       24284625
chr15:101143101-101143102(-) m6A exon       24981863
chr15:101143109-101143110(-) m6A exon       24981863
chr15:101143159-101143160(-) m6A exon       24981863
chr15:101143404-101143405(-) m6A exon       -
chr15:101143410-101143411(-) m6A exon       -
chr15:101143420-101143421(-) m6A exon       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-143-5p
Exosome Breast milk     22211110
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
LINS1
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-143-5p
Interactor2: LINS1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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