Basic Information:

  VIRBase ID:  

HHID00065843

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-138-2-3p:  MIMAT0004596          RBM38:  NM_017495     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-138-2-3p	RBM38
miRBase Accession/Entrez ID	MIMAT0004596	55544
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	dJ800J21.2//HSRNASEB//RNPC1//SEB4B//SEB4D

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-138-2-3p	rs1170600604 chr16:56858590    A/G rs564542140 chr16:56858595    T/C rs763657121 chr16:56858584    G/A rs765169127 chr16:56858583    C/T rs1198277453 chr16:56858578    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RBM38	chr20:55981776(+) A-I      intronic chr20:55978835(+) A-I      intronic chr20:55981862(+) A-I      intronic chr20:55977133(+) A-I      intronic chr20:55978807(+) A-I      intronic chr20:55978864(+) A-I      intronic chr20:55978819(+) A-I      intronic chr20:55981970(+) A-I      intronic chr20:55981991(+) A-I      intronic chr20:55978867(+) A-I      intronic chr20:55978808(+) A-I      intronic chr20:55978739(+) A-I      intronic chr20:55981939(+) A-I      intronic chr20:55981903(+) A-I      intronic chr20:55981864(+) A-I      intronic chr20:55978938(+) A-I      intronic chr20:55978928(+) A-I      intronic chr20:55978912(+) A-I      intronic chr20:55977026(+) A-I      intronic chr20:55977083(+) A-I      intronic chr20:55977224(+) A-I      intronic chr20:55977025(+) A-I      intronic chr20:55978950(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RBM38	chr20:55966725-55966726(+) m6A CDS       24209618 chr20:55967752-55967753(+) m6A 3'UTR//CDS       24284625 chr20:55967758-55967759(+) m6A 3'UTR//CDS       24284625 chr20:55967791-55967792(+) m6A 3'UTR//CDS       24284625 chr20:55968381-55968382(+) m6A 3'UTR//CDS//intron       24284625 chr20:55982922-55982923(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:55982949-55982950(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:55983030-55983031(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:55983060-55983061(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:55983114-55983115(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:55983133-55983134(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:55983265-55983266(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr20:55983292-55983293(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr20:55983321-55983322(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr20:55983344-55983345(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr20:55983399-55983400(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr20:55983637-55983638(+) m6A 3'UTR       24284625//24981863 chr20:55983658-55983659(+) m6A 3'UTR       24284625//24981863 chr20:55983765-55983766(+) m6A 3'UTR       24284625//24981863 chr20:55983840-55983841(+) m6A 3'UTR       24284625//24981863 chr20:55983897-55983898(+) m6A 3'UTR       24284625//24981863 chr20:55983954-55983955(+) m6A 3'UTR       24284625 chr20:55984181-55984182(+) m6A 3'UTR       24284625//25456834 chr20:55984239-55984240(+) m6A 3'UTR       24284625//25456834 chr20:55984287-55984288(+) m6A 3'UTR       24284625//25456834

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-138-2-3p	Exosome Jurkat-derived T cell line (J77cl20)     21505438 Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	RBM38	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-138-2-3p
Interactor2: RBM38

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.