Detail Information

Basic Information:


  VIRBase ID:  

HHID00065762

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-124-5p:           SOX9:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-124-5p SOX9
miRBase
Accession/Entrez ID		 MIMAT0004591 6662
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CMD1//CMPD1//SRA1//SRXX2//SRXY10

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-124-5p
rs1160219511 chr8:64379184    C/T
rs1261326747 chr8:64379185    G/A
rs1334649236 chr8:64379183    G/A
rs1344491363 chr8:64379192    G/A
rs1280076135 chr20:63178514    C/T
rs1340798465 chr20:63178533    G/C
rs764591061 chr20:63178525    C/T
rs760972715 chr20:63178520    C/A
rs775858016 chr20:63178517    G/A

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SOX9
chr17:70117184-70117185(+) m6A 5'UTR       24981863
chr17:70117195-70117196(+) m6A 5'UTR       24981863
chr17:70117212-70117213(+) m6A 5'UTR       24981863
chr17:70117235-70117236(+) m6A 5'UTR       24981863
chr17:70117351-70117352(+) m6A 5'UTR       24981863
chr17:70117617-70117618(+) m6A CDS       24284625//24981863
chr17:70117656-70117657(+) m6A CDS       24284625//24981863
chr17:70117665-70117666(+) m6A CDS       24284625//24981863
chr17:70117683-70117684(+) m6A CDS       24284625//24981863
chr17:70117731-70117732(+) m6A CDS       24981863
chr17:70117833-70117834(+) m6A CDS       -
chr17:70117905-70117906(+) m6A CDS       24209618
chr17:70118930-70118931(+) m6A CDS       24284625//24209618//24981863
chr17:70119724-70119725(+) m6A CDS       24209618
chr17:70119789-70119790(+) m6A CDS       -
chr17:70120337-70120338(+) m6A CDS       24284625//24209618//24981863
chr17:70120406-70120407(+) m6A CDS       24284625//24209618//24981863//22608085
chr17:70120471-70120472(+) m6A CDS       24284625//24209618//24981863//22608085
chr17:70120494-70120495(+) m6A CDS       24284625//24209618//24981863//22608085
chr17:70120592-70120593(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr17:70120613-70120614(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr17:70120677-70120678(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr17:70120716-70120717(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr17:70120722-70120723(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr17:70120810-70120811(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr17:70120815-70120816(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr17:70120824-70120825(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr17:70120898-70120899(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-124-5p
Exosome Plasma     23663360
Exosome Serum     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Urine     -
SOX9
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-124-5p
Interactor2: SOX9

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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