Basic Information:

  VIRBase ID:  

HHID00065737

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30b-3p:  MIMAT0004589          DENND2D:  NM_024901     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-30b-3p	DENND2D
miRBase Accession/Entrez ID	MIMAT0004589	79961
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-30b-3p	rs1160794252 chr8:134800541    A/G rs761170520 chr8:134800545    A/C rs776207215 chr8:134800535    G/GT rs1293522812 chr8:134800547    C/T rs1407185230 chr8:134800550    C/T rs1435060162 chr8:134800546    C/T rs766838703 chr8:134800548    T/C

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DENND2D	chr1:111729834-111729835(-) m6A 3'UTR//exon       27773535 chr1:111729882-111729883(-) m6A 3'UTR//exon       24981863//28052920//27773535 chr1:111729943-111729944(-) m6A 3'UTR//exon       28052920//27773535 chr1:111729964-111729965(-) m6A 3'UTR//exon       28052920//26404942//27773535 chr1:111730010-111730011(-) m6A 3'UTR//exon       24981863//28052920//26404942//27773535//27371828 chr1:111730042-111730043(-) m6A 3'UTR//exon       24981863//28052920//26404942//27773535//27371828 chr1:111730084-111730085(-) m6A 3'UTR//exon       24981863//28052920//26404942//27773535//27371828 chr1:111730145-111730146(-) m6A 3'UTR//exon       24981863//28052920//26404942//27773535//27371828 chr1:111730180-111730181(-) m6A 3'UTR//exon       24981863//28052920//26404942//27773535//27371828 chr1:111730237-111730238(-) m6A CDS//exon       24981863//28052920//26404942//27773535//27371828 chr1:111730250-111730251(-) m6A CDS//exon       24981863//28052920//26404942//27773535 chr1:111730259-111730260(-) m6A CDS//exon       24981863//28052920//26404942//27773535 chr1:111730268-111730269(-) m6A CDS//exon       24981863//28052920//26404942//27773535 chr1:111730809-111730810(-) m6A CDS//exon       24981863 chr1:111742771-111742772(-) m6A exon//intron       - chr1:111742776-111742777(-) m6A exon//intron       - chr1:111743168-111743169(-) m6A 5'UTR//intron       27371828 chr1:111743206-111743207(-) m6A 5'UTR//intron       27371828 chr1:111743228-111743229(-) m6A 5'UTR//intron       27371828 chr1:111746936-111746937(-) m6A CDS//exon       27371828 chr1:111747047-111747048(-) m6A exon       27371828 chr1:111747091-111747092(-) m6A exon       27371828

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-30b-3p	Exosome Breast milk     22211110 Exosome Plasma     23663360 Exosome Human mast cell line (HMC-1)     24009880 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     -
	DENND2D	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-30b-3p
Interactor2: DENND2D

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.