Basic Information:

  VIRBase ID:  

HHID00065710

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30b-3p:  MIMAT0004589          SRGN:  NM_001321054     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-30b-3p	SRGN
miRBase Accession/Entrez ID	MIMAT0004589	5552
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	PPG//PRG//PRG1

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-30b-3p	rs1160794252 chr8:134800541    A/G rs761170520 chr8:134800545    A/C rs776207215 chr8:134800535    G/GT rs1293522812 chr8:134800547    C/T rs1407185230 chr8:134800550    C/T rs1435060162 chr8:134800546    C/T rs766838703 chr8:134800548    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SRGN	chr10:70854394(+) A-I      intronic chr10:70854605(+) A-I      intronic chr10:70854610(+) A-I      intronic chr10:70854620(+) A-I      intronic chr10:70855481(+) A-I      intronic chr10:70855490(+) A-I      intronic chr10:70855491(+) A-I      intronic chr10:70861647(+) A-I      intronic chr10:70862918(+) A-I      intronic chr10:70862956(+) A-I      intronic chr10:70858537(+) A-I      intronic chr10:70861646(+) A-I      intronic chr10:70858577(+) A-I      intronic chr10:70858538(+) A-I      intronic chr10:70863256(+) A-I      intronic chr10:70859776(+) A-I      intronic chr10:70859645(+) A-I      intronic chr10:70861569(+) A-I      intronic chr10:70861644(+) A-I      intronic chr10:70854911(+) A-I      intronic chr10:70863264(+) A-I      intronic chr10:70854592(+) A-I      intronic chr10:70861694(+) A-I      intronic chr10:70861707(+) A-I      intronic chr10:70861760(+) A-I      intronic chr10:70854970(+) A-I      intronic chr10:70855426(+) A-I      intronic chr10:70855433(+) A-I      intronic chr10:70861809(+) A-I      intronic chr10:70860087(+) A-I      intronic chr10:70862776(+) A-I      intronic chr10:70862825(+) A-I      intronic chr10:70855570(+) A-I      intronic chr10:70862835(+) A-I      intronic chr10:70862845(+) A-I      intronic chr10:70855578(+) A-I      intronic chr10:70862841(+) A-I      intronic chr10:70855610(+) A-I      intronic chr10:70858460(+) A-I      intronic chr10:70859289(+) A-I      intronic chr10:70863035(+) A-I      intronic chr10:70862969(+) A-I      intronic chr10:70862861(+) A-I      intronic chr10:70862876(+) A-I      intronic chr10:70858465(+) A-I      intronic chr10:70862985(+) A-I      intronic chr10:70863128(+) A-I      intronic chr10:70863134(+) A-I      intronic chr10:70858482(+) A-I      intronic chr10:70858628(+) A-I      intronic chr10:70863287(+) A-I      intronic chr10:70863137(+) A-I      intronic chr10:70857457(+) A-I      intronic chr10:70854470(+) A-I      intronic chr10:70858695(+) A-I      intronic chr10:70859117(+) A-I      intronic chr10:70859186(+) A-I      intronic chr10:70854486(+) A-I      intronic chr10:70863219(+) A-I      intronic chr10:70859243(+) A-I      intronic chr10:70859263(+) A-I      intronic chr10:70859086(+) A-I      intronic chr10:70859290(+) A-I      intronic chr10:70861570(+) A-I      intronic chr10:70860048(+) A-I      intronic chr10:70860095(+) A-I      intronic chr10:70859322(+) A-I      intronic chr10:70854638(+) A-I      intronic chr10:70863152(+) A-I      intronic chr10:70863045(+) A-I      intronic chr10:70858573(+) A-I      intronic chr10:70854401(+) A-I      intronic chr10:70863244(+) A-I      intronic chr10:70858693(+) A-I      intronic chr10:70863148(+) A-I      intronic chr10:70862957(+) A-I      intronic chr10:70859296(+) A-I      intronic chr10:70859599(+) A-I      intronic chr10:70861754(+) A-I      intronic chr10:70859812(+) A-I      intronic chr10:70854925(+) A-I      intronic chr10:70858351(+) A-I      intronic chr10:70854809(+) A-I      intronic chr10:70854445(+) A-I      intronic chr10:70859323(+) A-I      intronic chr10:70858277(+) A-I      intronic chr10:70854448(+) A-I      intronic chr10:70857582(+) A-I      intronic chr10:70861643(+) A-I      intronic chr10:70858323(+) A-I      intronic chr10:70862796(+) A-I      intronic chr10:70862800(+) A-I      intronic chr10:70854400(+) A-I      intronic chr10:70859261(+) A-I      intronic chr10:70859854(+) A-I      intronic chr10:70860133(+) A-I      intronic chr10:70859725(+) A-I      intronic chr10:70861625(+) A-I      intronic chr10:70855434(+) A-I      intronic chr10:70861702(+) A-I      intronic chr10:70853476(+) A-I      intronic chr10:70863052(+) A-I      intronic chr10:70862881(+) A-I      intronic chr10:70854802(+) A-I      intronic chr10:70854949(+) A-I      intronic chr10:70855579(+) A-I      intronic chr10:70860992(+) A-I      intronic chr10:70859967(+) A-I      intronic chr10:70857368(+) A-I      intronic chr10:70863149(+) A-I      intronic chr10:70854544(+) A-I      intronic chr10:70854593(+) A-I      intronic chr10:70859270(+) A-I      intronic chr10:70859762(+) A-I      intronic chr10:70859598(+) A-I      intronic chr10:70856670(+) A-I      intronic chr10:70859174(+) A-I      intronic chr10:70860094(+) A-I      intronic chr10:70859156(+) A-I      intronic chr10:70859313(+) A-I      intronic chr10:70859855(+) A-I      intronic chr10:70859183(+) A-I      intronic chr10:70853633(+) A-I      intronic chr10:70861588(+) A-I      intronic chr10:70855638(+) A-I      intronic chr10:70861645(+) A-I      intronic chr10:70854449(+) A-I      intronic chr10:70851551(+) A-I      intronic chr10:70854887(+) A-I      intronic chr10:70856751(+) A-I      intronic chr10:70856644(+) A-I      intronic chr10:70863143(+) A-I      intronic chr10:70854827(+) A-I      intronic chr10:70859182(+) A-I      intronic chr10:70861697(+) A-I      intronic chr10:70859931(+) A-I      intronic chr10:70858556(+) A-I      intronic chr10:70862896(+) A-I      intronic chr10:70857581(+) A-I      intronic chr10:70862893(+) A-I      intronic chr10:70858318(+) A-I      intronic chr10:70858589(+) A-I      intronic chr10:70854541(+) A-I      intronic chr10:70852316(+) A-I      intronic chr10:70855628(+) A-I      intronic chr10:70859898(+) A-I      intronic chr10:70854880(+) A-I      intronic chr10:70858692(+) A-I      intronic chr10:70861757(+) A-I      intronic chr10:70859131(+) A-I      intronic chr10:70859225(+) A-I      intronic chr10:70858579(+) A-I      intronic chr10:70854966(+) A-I      intronic chr10:70862870(+) A-I      intronic chr10:70857445(+) A-I      intronic chr10:70858278(+) A-I      intronic chr10:70862875(+) A-I      intronic chr10:70858605(+) A-I      intronic chr10:70861574(+) A-I      intronic chr10:70862975(+) A-I      intronic chr10:70859195(+) A-I      intronic chr10:70859726(+) A-I      intronic chr10:70858569(+) A-I      intronic chr10:70855518(+) A-I      intronic chr10:70858622(+) A-I      intronic chr10:70860957(+) A-I      intronic chr10:70859953(+) A-I      intronic chr10:70859824(+) A-I      intronic chr10:70862978(+) A-I      intronic chr10:70854438(+) A-I      intronic chr10:70863214(+) A-I      intronic chr10:70854462(+) A-I      intronic chr10:70861725(+) A-I      intronic chr10:70858688(+) A-I      intronic chr10:70854917(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SRGN	chr10:70859855(+) A-I intron -    22327324 chr10:70859131(+) A-I intron -    21960545 chr10:70859195(+) A-I intron -    21960545 chr10:70864562(+) G-A intron -    21725310 chr10:70854400(+) A-G intron -    22484847 chr10:70854445(+) A-G intron -    22484847 chr10:70859131(+) A-G intron -    22484847 chr10:70859182(+) A-G intron -    22484847 chr10:70859854(+) A-G intron -    22484847 chr10:70859855(+) A-G intron -    22484847 chr10:70860095(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SRGN	chr10:70847901-70847902(+) m6A 5'UTR//exon       24981863//26404942 chr10:70856887-70856888(+) m6A CDS//intron       26404942 chr10:70856902-70856903(+) m6A CDS//intron       26404942 chr10:70856921-70856922(+) m6A CDS//intron       26404942 chr10:70856933-70856934(+) m6A CDS//intron       26404942 chr10:70856973-70856974(+) m6A CDS//intron       26404942 chr10:70863643-70863644(+) m6A CDS//exon       26404942 chr10:70863673-70863674(+) m6A CDS//exon       26404942 chr10:70863749-70863750(+) m6A CDS//exon       26404942 chr10:70863826-70863827(+) m6A CDS//exon       26404942 chr10:70863835-70863836(+) m6A CDS//exon       26404942 chr10:70863954-70863955(+) m6A 3'UTR//exon       26404942 chr10:70863980-70863981(+) m6A 3'UTR//exon       26404942 chr10:70864231-70864232(+) m6A 3'UTR//exon       26404942 chr10:70864281-70864282(+) m6A 3'UTR//exon       26404942 chr10:70864301-70864302(+) m6A 3'UTR       26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-30b-3p	Exosome Breast milk     22211110 Exosome Plasma     23663360 Exosome Human mast cell line (HMC-1)     24009880 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     -
	SRGN	Cytosol HeLa-S3 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-30b-3p
Interactor2: SRGN

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.