Detail Information

Basic Information:


  VIRBase ID:  

HHID00065484

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-214-5p:           PRPF4:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-214-5p PRPF4
miRBase
Accession/Entrez ID		 MIMAT0004564 9128
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HPRP4//HPRP4P//PRP4//Prp4p//RP70//SNRNP60

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-214-5p
rs747554459 chr1:172138858    C/T
rs748757777 chr1:172138868    G/A
rs768291010 chr1:172138869    T/C
rs779765684 chr1:172138867    T/C
rs1206615501 chr1:172138871    G/A
rs1266122414 chr1:172138876    G/A
rs1322177954 chr1:172138872    A/G
rs755676659 chr1:172138865    A/C
rs755676659 chr1:172138865    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PRPF4
chr9:116052318(+) A-I      intronic
chr9:116052304(+) A-I      intronic
chr9:116052242(+) A-I      intronic
chr9:116052393(+) A-I      intronic
chr9:116047865(+) A-I      intronic
chr9:116052379(+) A-I      intronic
chr9:116039849(+) A-I      intronic
chr9:116054414(+) A-I      3'UTR
chr9:116054435(+) A-I      3'UTR
chr9:116054346(+) A-I      3'UTR
chr9:116054291(+) A-I      3'UTR
chr9:116054413(+) A-I      3'UTR
chr9:116054237(+) A-I      3'UTR
chr9:116043201(+) A-I      intronic
chr9:116043221(+) A-I      intronic
chr9:116039212(+) A-I      intronic
chr9:116047623(+) A-I      intronic
chr9:116039175(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PRPF4
chr9:116054346(+) A-I intron -    22327324
chr9:116054413(+) A-I intron -    22327324
chr9:116054435(+) A-I intron -    22327324
chr9:116047521(+) A-G intron -    22484847
chr9:116047554(+) A-G intron -    22484847
chr9:116048090(+) A-G intron -    22484847
chr9:116054252(+) G-T intron -    22484847
chr9:116054291(+) A-G intron -    22484847
chr9:116054346(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PRPF4
chr9:116037693-116037694(+) m6A 5'UTR       24209618//24981863//27773535//27371828
chr9:116037715-116037716(+) m6A 5'UTR       24209618//24981863//27773535//27371828//22608085
chr9:116037735-116037736(+) m6A 5'UTR       24209618//24981863//27773535//27371828//22608085
chr9:116037749-116037750(+) m6A 5'UTR       24209618//24981863//27773535//27371828//22608085
chr9:116037776-116037777(+) m6A 5'UTR       24209618//24981863//27773535//27371828//22608085
chr9:116038836-116038837(+) m6A CDS       -
chr9:116038877-116038878(+) m6A CDS       -
chr9:116038961-116038962(+) m6A CDS       24981863//27773535
chr9:116053224-116053225(+) m6A CDS       22575960
chr9:116053269-116053270(+) m6A CDS       22575960
chr9:116053758-116053759(+) m6A CDS       24284625//24209618//22575960
chr9:116053829-116053830(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr9:116053913-116053914(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr9:116053957-116053958(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr9:116053963-116053964(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr9:116054055-116054056(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22575960//22608085
chr9:116054127-116054128(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22575960//22608085
chr9:116054175-116054176(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085
chr9:116054184-116054185(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085
chr9:116054483-116054484(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr9:116054580-116054581(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr9:116054614-116054615(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr9:116054646-116054647(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr9:116054701-116054702(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr9:116054759-116054760(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr9:116054794-116054795(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr9:116054851-116054852(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22608085
chr9:116054856-116054857(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr9:116054929-116054930(+) m6A 3'UTR       24284625//24981863//27773535//22608085
chr9:116054949-116054950(+) m6A 3'UTR       24284625//24981863//27773535//22608085
chr9:116054968-116054969(+) m6A 3'UTR       24284625//24981863//27773535//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-214-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
PRPF4
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-214-5p
Interactor2: PRPF4

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

Starting a new search, please wait ...