Basic Information:

  VIRBase ID:  

HHID00065008

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-7-1-3p:  MIMAT0004553          LBH:  NM_030915     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-7-1-3p	LBH
miRBase Accession/Entrez ID	MIMAT0004553	81606
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-7-1-3p	rs1419148287 chr9:83969783    T/C rs1463372700 chr9:83969781    T/G rs767086173 chr9:83969775    G/A rs772876693 chr9:83969780    CTG/C rs775309693 chr9:83969778    G/C rs1411851112 chr9:83969779    ACTGTGATTTGTTGT/A rs760333621 chr9:83969787    T/C rs767563035 chr9:83969791    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	LBH	chr2:30474517(+) A-I      intronic chr2:30474483(+) A-I      intronic chr2:30474472(+) A-I      intronic chr2:30465173(+) A-I      intronic chr2:30461806(+) A-I      intronic chr2:30474448(+) A-I      intronic chr2:30474054(+) A-I      intronic chr2:30474024(+) A-I      intronic chr2:30468905(+) A-I      intronic chr2:30467543(+) A-I      intronic chr2:30466538(+) A-I      intronic chr2:30466471(+) A-I      intronic chr2:30479464(+) A-I      intronic chr2:30465210(+) A-I      intronic chr2:30479461(+) A-I      intronic chr2:30465189(+) A-I      intronic chr2:30465190(+) A-I      intronic chr2:30536526(+) A-I      intronic chr2:30469963(+) A-I      intronic chr2:30479548(+) A-I      intronic chr2:30467612(+) A-I      intronic chr2:30467510(+) A-I      intronic chr2:30465293(+) A-I      intronic chr2:30479500(+) A-I      intronic chr2:30527426(+) A-I      intronic chr2:30465239(+) A-I      intronic chr2:30536534(+) A-I      intronic chr2:30479560(+) A-I      intronic chr2:30467506(+) A-I      intronic chr2:30464604(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	LBH	chr2:30455211-30455212(+) m6A 5'UTR//exon//intron       25456834 chr2:30455237-30455238(+) m6A 5'UTR//exon//intron       25456834 chr2:30455314-30455315(+) m6A 5'UTR//exon//intron       25456834 chr2:30455369-30455370(+) m6A 5'UTR//exon//intron       25456834 chr2:30457314-30457315(+) m6A CDS//exon       - chr2:30480308-30480309(+) m6A 3'UTR//CDS//exon//intron       24981863 chr2:30480336-30480337(+) m6A 3'UTR//CDS//exon//intron       24209618//24981863 chr2:30480344-30480345(+) m6A 3'UTR//CDS//exon//intron       24209618//24981863 chr2:30480369-30480370(+) m6A 3'UTR//CDS//exon//intron       24209618//24981863 chr2:30480460-30480461(+) m6A 3'UTR//CDS//exon//intron       24209618//24981863//26404942 chr2:30480498-30480499(+) m6A 3'UTR//exon//intron       24209618//24981863//26404942 chr2:30480535-30480536(+) m6A 3'UTR//exon//intron       24209618//24981863//26404942 chr2:30480791-30480792(+) m6A 3'UTR//exon//intron       24981863 chr2:30480876-30480877(+) m6A 3'UTR//exon//intron       24981863//26404942 chr2:30480893-30480894(+) m6A 3'UTR//exon//intron       24981863//26404942 chr2:30480934-30480935(+) m6A 3'UTR//intron       24981863//26404942 chr2:30480948-30480949(+) m6A 3'UTR//intron       24981863//26404942 chr2:30480973-30480974(+) m6A 3'UTR//intron       24981863//26404942 chr2:30480994-30480995(+) m6A 3'UTR//intron       26404942 chr2:30481004-30481005(+) m6A 3'UTR//intron       26404942 chr2:30481900-30481901(+) m6A 3'UTR//intron       24981863//26404942 chr2:30481948-30481949(+) m6A 3'UTR//intron       24981863//26404942 chr2:30481971-30481972(+) m6A 3'UTR//intron       24981863//26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-7-1-3p	Exosome Jurkat-derived T cell line (J77cl20)     21505438 Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
	LBH	Chromatin K562 cells     - Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-7-1-3p
Interactor2: LBH

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.