Detail Information

Basic Information:


  VIRBase ID:  

HHID00064913

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30c-2-3p PABPC1P4
miRBase
Accession/Entrez ID		 MIMAT0004550 341315
Organism Homo sapiens Homo sapiens
Category miRNA pseudo
Alias - PABPCP5//PABPL2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30c-2-3p
rs1262929323 chr6:71376964    A/G
rs1413659455 chr6:71376968    T/C
rs1421032991 chr6:71376975    C/A
rs1421032991 chr6:71376975    C/G
rs1488181071 chr6:71376967    G/T
rs747913643 chr6:71376976    C/A
rs760276048 chr6:71376974    G/C
rs775896072 chr6:71376969    A/G

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PABPC1P4
chr12:64215928-64215929(+) m6A exon       -
chr12:64215967-64215968(+) m6A exon       -
chr12:64216003-64216004(+) m6A exon       -
chr12:64216114-64216115(+) m6A exon       -
chr12:64216566-64216567(+) m6A exon       -
chr12:64216609-64216610(+) m6A exon       -
chr12:64216614-64216615(+) m6A exon       -
chr12:64217035-64217036(+) m6A exon       24981863
chr12:64217085-64217086(+) m6A exon       24981863
chr12:64217101-64217102(+) m6A exon       24981863
chr12:64217118-64217119(+) m6A exon       24981863
chr12:64217169-64217170(+) m6A exon       -
chr12:64217190-64217191(+) m6A exon       -
chr12:64217544-64217545(+) m6A exon       -
chr12:64217596-64217597(+) m6A exon       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30c-2-3p
Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20)     21505438
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Serum     24797360
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
PABPC1P4
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30c-2-3p
Gemcitabine 60750 Drug interaction    RC00006870
Eloxatine 5310940 Drug interaction    RC00006871
5-Fluorouracil 3385 Drug interaction    RC00006869
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30c-2-3p
Cisplatin 5702198       27506865

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30c-2-3p
Interactor2: PABPC1P4

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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