Detail Information

Basic Information:


  VIRBase ID:  

HHID00064912

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30c-2-3p:           TOMM5:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30c-2-3p TOMM5
miRBase
Accession/Entrez ID		 MIMAT0004550 401505
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - bA613M10.3//C9orf105//Tom5

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30c-2-3p
rs1262929323 chr6:71376964    A/G
rs1413659455 chr6:71376968    T/C
rs1421032991 chr6:71376975    C/A
rs1421032991 chr6:71376975    C/G
rs1488181071 chr6:71376967    G/T
rs747913643 chr6:71376976    C/A
rs760276048 chr6:71376974    G/C
rs775896072 chr6:71376969    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TOMM5
chr9:37592030(-) A-I      intronic
chr9:37590343(-) A-I      intronic
chr9:37590336(-) A-I      intronic
chr9:37590334(-) A-I      intronic
chr9:37590198(-) A-I      intronic
chr9:37590280(-) A-I      intronic
chr9:37589687(-) A-I      intronic
chr9:37589688(-) A-I      intronic
chr9:37589675(-) A-I      intronic
chr9:37590272(-) A-I      intronic
chr9:37592052(-) A-I      intronic
chr9:37592047(-) A-I      intronic
chr9:37589659(-) A-I      intronic
chr9:37589722(-) A-I      intronic
chr9:37590257(-) A-I      intronic
chr9:37590186(-) A-I      intronic
chr9:37590187(-) A-I      intronic
chr9:37590182(-) A-I      intronic
chr9:37589673(-) A-I      intronic
chr9:37591581(-) A-I      intronic
chr9:37591677(-) A-I      intronic
chr9:37591643(-) A-I      intronic
chr9:37592031(-) A-I      intronic
chr9:37592107(-) A-I      intronic
chr9:37590185(-) A-I      intronic
chr9:37590276(-) A-I      intronic
chr9:37589667(-) A-I      intronic
chr9:37589808(-) A-I      intronic
chr9:37589732(-) A-I      intronic
chr9:37589683(-) A-I      intronic
chr9:37590377(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TOMM5
chr9:37589683(-) A-I intron -    15342557
chr9:37589737(-) A-I intron -    15342557
chr9:37589738(-) A-I intron -    15342557
chr9:37590187(-) A-I intron -    15342557
chr9:37590224(-) A-I intron -    15342557
chr9:37590317(-) A-I intron -    15342557
chr9:37590372(-) A-I intron -    15342557
chr9:37589737(-) A-G intron -    22484847
chr9:37589738(-) A-G intron -    22484847
chr9:37590187(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TOMM5
chr9:37582647-37582648(-) m6A 3'UTR       27773535
chr9:37582700-37582701(-) m6A 3'UTR       27773535
chr9:37582804-37582805(-) m6A 3'UTR       27773535
chr9:37582958-37582959(-) m6A 3'UTR       27773535
chr9:37582974-37582975(-) m6A 3'UTR       27773535
chr9:37583032-37583033(-) m6A 3'UTR       27773535
chr9:37583089-37583090(-) m6A 3'UTR       27773535
chr9:37588618-37588619(-) m6A 3'UTR//intron       27773535
chr9:37588719-37588720(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr9:37588763-37588764(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr9:37588786-37588787(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085
chr9:37588799-37588800(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085
chr9:37588886-37588887(-) m6A 3'UTR//CDS       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085
chr9:37588891-37588892(-) m6A 3'UTR//CDS       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085
chr9:37588904-37588905(-) m6A 3'UTR//CDS       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr9:37592318-37592319(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//27371828//22608085
chr9:37592378-37592379(-) m6A CDS//intron       24284625//24209618//27773535//27371828//22575960
chr9:37592440-37592441(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr9:37592494-37592495(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr9:37592620-37592621(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30c-2-3p
Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20)     21505438
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Serum     24797360
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
TOMM5
Exosome Blood     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30c-2-3p
Gemcitabine 60750 Drug interaction    RC00006870
Eloxatine 5310940 Drug interaction    RC00006871
5-Fluorouracil 3385 Drug interaction    RC00006869
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30c-2-3p
Cisplatin 5702198       27506865

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30c-2-3p
Interactor2: TOMM5

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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