Detail Information

Basic Information:


  VIRBase ID:  

HHID00064908

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30c-2-3p:           ZNF367:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30c-2-3p ZNF367
miRBase
Accession/Entrez ID		 MIMAT0004550 195828
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - AFF29//CDC14B//ZFF29

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30c-2-3p
rs1262929323 chr6:71376964    A/G
rs1413659455 chr6:71376968    T/C
rs1421032991 chr6:71376975    C/A
rs1421032991 chr6:71376975    C/G
rs1488181071 chr6:71376967    G/T
rs747913643 chr6:71376976    C/A
rs760276048 chr6:71376974    G/C
rs775896072 chr6:71376969    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ZNF367
chr9:99173428(-) A-I      intronic
chr9:99173359(-) A-I      intronic
chr9:99172527(-) A-I      intronic
chr9:99153042(-) A-I      intronic
chr9:99172485(-) A-I      intronic
chr9:99172397(-) A-I      intronic
chr9:99172396(-) A-I      intronic
chr9:99153066(-) A-I      intronic
chr9:99172328(-) A-I      intronic
chr9:99169118(-) A-I      intronic
chr9:99159114(-) A-I      intronic
chr9:99169113(-) A-I      intronic
chr9:99169078(-) A-I      intronic
chr9:99165523(-) A-I      intronic
chr9:99165434(-) A-I      intronic
chr9:99165422(-) A-I      intronic
chr9:99165392(-) A-I      intronic
chr9:99165390(-) A-I      intronic
chr9:99163900(-) A-I      intronic
chr9:99163863(-) A-I      intronic
chr9:99163853(-) A-I      intronic
chr9:99163839(-) A-I      intronic
chr9:99163770(-) A-I      intronic
chr9:99178168(-) A-I      intronic
chr9:99163686(-) A-I      intronic
chr9:99162669(-) A-I      intronic
chr9:99162656(-) A-I      intronic
chr9:99153140(-) A-I      intronic
chr9:99174242(-) A-I      intronic
chr9:99153071(-) A-I      intronic
chr9:99153022(-) A-I      intronic
chr9:99152390(-) A-I      intronic
chr9:99152150(-) A-I      intronic
chr9:99152115(-) A-I      intronic
chr9:99174221(-) A-I      intronic
chr9:99174207(-) A-I      intronic
chr9:99174202(-) A-I      intronic
chr9:99174206(-) A-I      intronic
chr9:99152921(-) A-I      intronic
chr9:99152961(-) A-I      intronic
chr9:99152900(-) A-I      intronic
chr9:99152948(-) A-I      intronic
chr9:99152341(-) A-I      intronic
chr9:99178281(-) A-I      intronic
chr9:99165327(-) A-I      intronic
chr9:99165384(-) A-I      intronic
chr9:99153083(-) A-I      intronic
chr9:99162588(-) A-I      intronic
chr9:99152332(-) A-I      intronic
chr9:99174248(-) A-I      intronic
chr9:99169351(-) A-I      intronic
chr9:99152963(-) A-I      intronic
chr9:99165420(-) A-I      intronic
chr9:99152406(-) A-I      intronic
chr9:99152425(-) A-I      intronic
chr9:99173420(-) A-I      intronic
chr9:99178148(-) A-I      intronic
chr9:99152456(-) A-I      intronic
chr9:99151578(-) A-I      intronic
chr9:99152306(-) A-I      intronic
chr9:99173262(-) A-I      intronic
chr9:99165445(-) A-I      intronic
chr9:99153113(-) A-I      intronic
chr9:99165043(-) A-I      intronic
chr9:99152168(-) A-I      intronic
chr9:99153125(-) A-I      intronic
chr9:99151410(-) A-I      intronic
chr9:99160743(-) A-I      intronic
chr9:99165027(-) A-I      intronic
chr9:99178283(-) A-I      intronic
chr9:99166687(-) A-I      intronic
chr9:99153000(-) A-I      intronic
chr9:99152903(-) A-I      intronic
chr9:99152152(-) A-I      intronic
chr9:99173077(-) A-I      intronic
chr9:99165363(-) A-I      intronic
chr9:99152279(-) A-I      intronic
chr9:99165309(-) A-I      intronic
chr9:99165541(-) A-I      intronic
chr9:99162589(-) A-I      intronic
chr9:99151579(-) A-I      intronic
chr9:99152962(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ZNF367
chr9:99152152(-) A-G intron -    22484847
chr9:99152909(-) A-G intron -    22484847
chr9:99152948(-) A-G intron -    22484847
chr9:99152949(-) A-G intron -    22484847
chr9:99152962(-) A-G intron -    22484847
chr9:99152963(-) A-G intron -    22484847
chr9:99162588(-) A-G intron -    22484847
chr9:99162589(-) A-G intron -    22484847
chr9:99162592(-) A-G intron -    22484847
chr9:99170102(-) T-C intron -    22484847
chr9:99170123(-) A-G intron -    22484847
chr9:99170124(-) G-C intron -    22484847
chr9:99170154(-) G-A intron -    22484847
chr9:99173586(-) A-T intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZNF367
chr9:99149101-99149102(-) m6A 3'UTR       27773535
chr9:99149964-99149965(-) m6A 3'UTR       27773535
chr9:99150083-99150084(-) m6A 3'UTR       27773535
chr9:99150143-99150144(-) m6A 3'UTR       27773535
chr9:99150176-99150177(-) m6A 3'UTR       27773535//22608085
chr9:99150191-99150192(-) m6A 3'UTR       27773535//22608085
chr9:99150274-99150275(-) m6A 3'UTR       24981863//27773535//22608085
chr9:99150296-99150297(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr9:99150358-99150359(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr9:99150512-99150513(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr9:99150663-99150664(-) m6A CDS       24284625//24209618//24981863//27371828//22575960//22608085
chr9:99154723-99154724(-) m6A CDS       27773535//27371828
chr9:99154736-99154737(-) m6A CDS       27773535//27371828
chr9:99154790-99154791(-) m6A CDS       27773535//27371828
chr9:99157126-99157127(-) m6A CDS       27773535//27371828
chr9:99157155-99157156(-) m6A CDS       27773535//27371828
chr9:99180279-99180280(-) m6A CDS       24209618//27371828//27773536
chr9:99180407-99180408(-) m6A 5'UTR       24209618//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30c-2-3p
Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20)     21505438
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Serum     24797360
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
ZNF367
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30c-2-3p
Gemcitabine 60750 Drug interaction    RC00006870
Eloxatine 5310940 Drug interaction    RC00006871
5-Fluorouracil 3385 Drug interaction    RC00006869
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30c-2-3p
Cisplatin 5702198       27506865

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30c-2-3p
Interactor2: ZNF367

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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