Basic Information:

  VIRBase ID:  

HHID00064905

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30c-2-3p:  MIMAT0004550          FAM91A1:  NM_001317917     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-30c-2-3p	FAM91A1
miRBase Accession/Entrez ID	MIMAT0004550	157769
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-30c-2-3p	rs1262929323 chr6:71376964    A/G rs1413659455 chr6:71376968    T/C rs1421032991 chr6:71376975    C/A rs1421032991 chr6:71376975    C/G rs1488181071 chr6:71376967    G/T rs747913643 chr6:71376976    C/A rs760276048 chr6:71376974    G/C rs775896072 chr6:71376969    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FAM91A1	chr8:124788229(+) A-I      intronic chr8:124787973(+) A-I      intronic chr8:124788098(+) A-I      intronic chr8:124809149(+) A-I      intronic chr8:124815276(+) A-I      intronic chr8:124816497(+) A-I      intronic chr8:124816611(+) A-I      intronic chr8:124809216(+) A-I      intronic chr8:124809048(+) A-I      intronic chr8:124809049(+) A-I      intronic chr8:124809174(+) A-I      intronic chr8:124795391(+) A-I      intronic chr8:124809180(+) A-I      intronic chr8:124809189(+) A-I      intronic chr8:124795148(+) A-I      intronic chr8:124809213(+) A-I      intronic chr8:124809207(+) A-I      intronic chr8:124815693(+) A-I      intronic chr8:124809233(+) A-I      intronic chr8:124824241(+) A-I      intronic chr8:124816524(+) A-I      intronic chr8:124808844(+) A-I      intronic chr8:124795323(+) A-I      intronic chr8:124793939(+) A-I      intronic chr8:124815349(+) A-I      intronic chr8:124793934(+) A-I      intronic chr8:124795336(+) A-I      intronic chr8:124816525(+) A-I      intronic chr8:124816610(+) A-I      intronic chr8:124815362(+) A-I      intronic chr8:124793999(+) A-I      intronic chr8:124815343(+) A-I      intronic chr8:124815298(+) A-I      intronic chr8:124808761(+) A-I      intronic chr8:124815651(+) A-I      intronic chr8:124808764(+) A-I      intronic chr8:124815680(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FAM91A1	chr8:124782226(+) C-T intron -    22484847 chr8:124793999(+) A-G intron -    22484847 chr8:124795336(+) A-G intron -    22484847 chr8:124804203(+) T-C intron -    22484847 chr8:124808761(+) A-G intron -    22484847 chr8:124808764(+) A-G intron -    22484847 chr8:124809233(+) A-G intron -    22484847 chr8:124815349(+) A-G intron -    22484847 chr8:124815651(+) A-G intron -    22484847 chr8:124815680(+) A-G intron -    22484847 chr8:124815693(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FAM91A1	chr8:124780701-124780702(+) m6A 5'UTR       24981863 chr8:124780712-124780713(+) m6A 5'UTR       24981863 chr8:124780785-124780786(+) m6A 5'UTR       24981863 chr8:124811798-124811799(+) Y 3'UTR//CDS       26075521 chr8:124818370-124818371(+) m6A 3'UTR//CDS       - chr8:124818379-124818380(+) m6A 3'UTR//CDS       - chr8:124818443-124818444(+) m6A 3'UTR//CDS       - chr8:124820515-124820516(+) m6A 3'UTR//CDS       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-30c-2-3p	Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20)     21505438 Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Serum     24797360 Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Cell line (HEK-293|HeLa)     22984580
	FAM91A1	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-30c-2-3p	Gemcitabine 60750 Drug interaction    RC00006870 Eloxatine 5310940 Drug interaction    RC00006871 5-Fluorouracil 3385 Drug interaction    RC00006869

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-30c-2-3p	Cisplatin 5702198       27506865

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-30c-2-3p
Interactor2: FAM91A1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.