Detail Information

Basic Information:


  VIRBase ID:  

HHID00064901

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30c-2-3p:           CCDC43:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30c-2-3p CCDC43
miRBase
Accession/Entrez ID		 MIMAT0004550 124808
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30c-2-3p
rs1262929323 chr6:71376964    A/G
rs1413659455 chr6:71376968    T/C
rs1421032991 chr6:71376975    C/A
rs1421032991 chr6:71376975    C/G
rs1488181071 chr6:71376967    G/T
rs747913643 chr6:71376976    C/A
rs760276048 chr6:71376974    G/C
rs775896072 chr6:71376969    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CCDC43
chr17:42757522(-) A-I      intronic
chr17:42757549(-) A-I      intronic
chr17:42757506(-) A-I      intronic
chr17:42757429(-) A-I      intronic
chr17:42757524(-) A-I      intronic
chr17:42762287(-) A-I      intronic
chr17:42757490(-) A-I      intronic
chr17:42762300(-) A-I      intronic
chr17:42762313(-) A-I      intronic
chr17:42757534(-) A-I      intronic
chr17:42757528(-) A-I      intronic
chr17:42758719(-) A-I      intronic
chr17:42762413(-) A-I      intronic
chr17:42762386(-) A-I      intronic
chr17:42762381(-) A-I      intronic
chr17:42762317(-) A-I      intronic
chr17:42757451(-) A-I      intronic
chr17:42757512(-) A-I      intronic
chr17:42757516(-) A-I      intronic
chr17:42758768(-) A-I      intronic
chr17:42757523(-) A-I      intronic
chr17:42757535(-) A-I      intronic
chr17:42762309(-) A-I      intronic
chr17:42762227(-) A-I      intronic
chr17:42761965(-) A-I      intronic
chr17:42761918(-) A-I      intronic
chr17:42761849(-) A-I      intronic
chr17:42757560(-) A-I      intronic
chr17:42758743(-) A-I      intronic
chr17:42757470(-) A-I      intronic
chr17:42758657(-) A-I      intronic
chr17:42765675(-) A-I      intronic
chr17:42765794(-) A-I      intronic
chr17:42757604(-) A-I      intronic
chr17:42758613(-) A-I      intronic
chr17:42764747(-) A-I      intronic
chr17:42758622(-) A-I      intronic
chr17:42758625(-) A-I      intronic
chr17:42758637(-) A-I      intronic
chr17:42758642(-) A-I      intronic
chr17:42758648(-) A-I      intronic
chr17:42758682(-) A-I      intronic
chr17:42764741(-) A-I      intronic
chr17:42757102(-) A-I      intronic
chr17:42764876(-) A-I      intronic
chr17:42764951(-) A-I      intronic
chr17:42764975(-) A-I      intronic
chr17:42765643(-) A-I      intronic
chr17:42765663(-) A-I      intronic
chr17:42757018(-) A-I      intronic
chr17:42757048(-) A-I      intronic
chr17:42757551(-) A-I      intronic
chr17:42757068(-) A-I      intronic
chr17:42757093(-) A-I      intronic
chr17:42757096(-) A-I      intronic
chr17:42757111(-) A-I      intronic
chr17:42757175(-) A-I      intronic
chr17:42757179(-) A-I      intronic
chr17:42757224(-) A-I      intronic
chr17:42757374(-) A-I      intronic
chr17:42757418(-) A-I      intronic
chr17:42757438(-) A-I      intronic
chr17:42758617(-) A-I      intronic
chr17:42764763(-) A-I      intronic
chr17:42757434(-) A-I      intronic
chr17:42765777(-) A-I      intronic
chr17:42757526(-) A-I      intronic
chr17:42761831(-) A-I      intronic
chr17:42765720(-) A-I      intronic
chr17:42761944(-) A-I      intronic
chr17:42761982(-) A-I      intronic
chr17:42764491(-) A-I      intronic
chr17:42757629(-) A-I      intronic
chr17:42757443(-) A-I      intronic
chr17:42757072(-) A-I      intronic
chr17:42757552(-) A-I      intronic
chr17:42757180(-) A-I      intronic
chr17:42757079(-) A-I      intronic
chr17:42757611(-) A-I      intronic
chr17:42757559(-) A-I      intronic
chr17:42757027(-) A-I      intronic
chr17:42758723(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CCDC43
chr17:42750579-42750580(-) m6A 3'UTR       27773535//22608085
chr17:42750675-42750676(-) m6A 3'UTR       27773535//22608085
chr17:42750703-42750704(-) m6A 3'UTR       27773535//22608085
chr17:42750771-42750772(-) m6A 3'UTR       24284625//27773535//22608085
chr17:42750820-42750821(-) m6A 3'UTR       24284625//22608085
chr17:42751502-42751503(-) m6A intron       24981863//22608085
chr17:42751625-42751626(-) m6A intron       24981863//22608085
chr17:42751655-42751656(-) m6A intron       24981863
chr17:42755719-42755720(-) m6A 3'UTR//intron       24981863//27773535
chr17:42756175-42756176(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22608085
chr17:42756191-42756192(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22608085
chr17:42756249-42756250(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22608085
chr17:42756293-42756294(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr17:42756314-42756315(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr17:42756319-42756320(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr17:42756353-42756354(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr17:42756364-42756365(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr17:42756398-42756399(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr17:42757969-42757970(-) m6A CDS//intron       24284625//24209618//24981863//27773535//27371828//22608085
chr17:42759137-42759138(-) m6A exon//intron       24209618//24981863//27773535
chr17:42759150-42759151(-) m6A exon//intron       24209618//24981863//27773535
chr17:42759189-42759190(-) m6A exon//intron       24209618//24981863//27773535//22608085
chr17:42759323-42759324(-) m6A exon//intron       24981863//27773535
chr17:42761272-42761273(-) m6A CDS//exon       24981863//27773535
chr17:42761322-42761323(-) m1A CDS//exon       26863196
chr17:42766960-42766961(-) m1A CDS//exon       26863196//26863410
chr17:42767014-42767015(-) m6A CDS//exon       25456834//24981863//27371828//22575960
chr17:42767134-42767135(-) m6A 5'UTR       25456834//24981863//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30c-2-3p
Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20)     21505438
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Serum     24797360
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
CCDC43
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HCC cell line (HepG2)     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30c-2-3p
Gemcitabine 60750 Drug interaction    RC00006870
Eloxatine 5310940 Drug interaction    RC00006871
5-Fluorouracil 3385 Drug interaction    RC00006869
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30c-2-3p
Cisplatin 5702198       27506865

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30c-2-3p
Interactor2: CCDC43

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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