Detail Information

Basic Information:


  VIRBase ID:  

HHID00064896

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30c-2-3p:           SIKE1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30c-2-3p SIKE1
miRBase
Accession/Entrez ID		 MIMAT0004550 80143
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - SIKE

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30c-2-3p
rs1262929323 chr6:71376964    A/G
rs1413659455 chr6:71376968    T/C
rs1421032991 chr6:71376975    C/A
rs1421032991 chr6:71376975    C/G
rs1488181071 chr6:71376967    G/T
rs747913643 chr6:71376976    C/A
rs760276048 chr6:71376974    G/C
rs775896072 chr6:71376969    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SIKE1
chr1:115312883(-) A-I      3'UTR
chr1:115312910(-) A-I      3'UTR
chr1:115312918(-) A-I      3'UTR
chr1:115312870(-) A-I      3'UTR
chr1:115316790(-) A-I      3'UTR
chr1:115318264(-) A-I      intronic
chr1:115321596(-) A-I      ncRNA
chr1:115312893(-) A-I      3'UTR
chr1:115318224(-) A-I      intronic
chr1:115321595(-) A-I      ncRNA
chr1:115318354(-) A-I      intronic
chr1:115318331(-) A-I      intronic
chr1:115318212(-) A-I      intronic
chr1:115312977(-) A-I      3'UTR
chr1:115318347(-) A-I      intronic
chr1:115318291(-) A-I      intronic
chr1:115318294(-) A-I      intronic
chr1:115312935(-) A-I      3'UTR
chr1:115318230(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SIKE1
chr1:115312893(-) A-G exon 3'UTR    22484847
chr1:115318279(-) T-A intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SIKE1
chr1:115312291-115312292(-) m6A 3'UTR       27773535
chr1:115312544-115312545(-) m6A 3'UTR       27773535
chr1:115312592-115312593(-) m6A 3'UTR       27773535
chr1:115312625-115312626(-) m6A 3'UTR       27773535
chr1:115312632-115312633(-) m6A 3'UTR       27773535
chr1:115312652-115312653(-) m6A 3'UTR       27773535
chr1:115314291-115314292(-) m6A 3'UTR       27773535
chr1:115314298-115314299(-) m6A 3'UTR       27773535
chr1:115314369-115314370(-) m6A 3'UTR       27773535
chr1:115316627-115316628(-) m6A 3'UTR       27773535
chr1:115316643-115316644(-) m6A 3'UTR       27773535
chr1:115316668-115316669(-) m6A 3'UTR       27773535
chr1:115316886-115316887(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr1:115316916-115316917(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr1:115316925-115316926(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr1:115316978-115316979(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22608085
chr1:115321558-115321559(-) m6A exon//intron       24209618//27773535
chr1:115321850-115321851(-) Am CDS//exon       -
chr1:115322735-115322736(-) m6A CDS//exon//intron       24209618
chr1:115322750-115322751(-) m6A CDS//exon//intron       24209618
chr1:115322765-115322766(-) m6A CDS//exon//intron       24209618
chr1:115322791-115322792(-) m6A CDS//exon//intron       24209618
chr1:115322807-115322808(-) m6A CDS//exon//intron       24209618//27773536
chr1:115322951-115322952(-) m6A exon//intron       27371828
chr1:115323073-115323074(-) m6A CDS//exon       27371828//27773536
chr1:115323086-115323087(-) m6A CDS//exon       27371828//27773536
chr1:115323296-115323297(-) m6A 5'UTR//exon       24981863//27371828//27773536//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30c-2-3p
Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20)     21505438
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Serum     24797360
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
SIKE1
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30c-2-3p
Gemcitabine 60750 Drug interaction    RC00006870
Eloxatine 5310940 Drug interaction    RC00006871
5-Fluorouracil 3385 Drug interaction    RC00006869
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30c-2-3p
Cisplatin 5702198       27506865

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30c-2-3p
Interactor2: SIKE1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

Starting a new search, please wait ...