Detail Information

Basic Information:


  VIRBase ID:  

HHID00064888

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30c-2-3p:           ABHD10:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30c-2-3p ABHD10
miRBase
Accession/Entrez ID		 MIMAT0004550 55347
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30c-2-3p
rs1262929323 chr6:71376964    A/G
rs1413659455 chr6:71376968    T/C
rs1421032991 chr6:71376975    C/A
rs1421032991 chr6:71376975    C/G
rs1488181071 chr6:71376967    G/T
rs747913643 chr6:71376976    C/A
rs760276048 chr6:71376974    G/C
rs775896072 chr6:71376969    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ABHD10
chr3:111705422(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ABHD10
chr3:111697878-111697879(+) m6A 5'UTR//exon       24981863
chr3:111697896-111697897(+) m6A 5'UTR//exon       24981863
chr3:111700637-111700638(+) m6A CDS//exon//intron       24981863
chr3:111700672-111700673(+) m6A CDS//exon//intron       24981863
chr3:111700681-111700682(+) m6A CDS//exon//intron       24981863
chr3:111710288-111710289(+) Y 3'UTR//CDS       26075521
chr3:111710324-111710325(+) m6A 3'UTR//CDS       24284625//24981863//26404942//22608085
chr3:111710359-111710360(+) m6A 3'UTR//CDS       24284625//24981863//26404942//27773535//22608085
chr3:111710471-111710472(+) m6A 3'UTR//CDS       24284625//24981863//26404942//27773535//22608085
chr3:111710503-111710504(+) m6A 3'UTR//CDS       24284625//24981863//26404942//27773535//22608085
chr3:111710593-111710594(+) m6A 3'UTR       26404942//27773535
chr3:111711613-111711614(+) m6A 3'UTR       27773535
chr3:111711638-111711639(+) m6A 3'UTR       27773535
chr3:111711653-111711654(+) m6A 3'UTR       27773535
chr3:111711679-111711680(+) m6A 3'UTR       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30c-2-3p
Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20)     21505438
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Serum     24797360
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
ABHD10
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30c-2-3p
Gemcitabine 60750 Drug interaction    RC00006870
Eloxatine 5310940 Drug interaction    RC00006871
5-Fluorouracil 3385 Drug interaction    RC00006869
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30c-2-3p
Cisplatin 5702198       27506865

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30c-2-3p
Interactor2: ABHD10

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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