Basic Information:

  VIRBase ID:  

HHID00064880

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30c-2-3p:  MIMAT0004550          PELO:  NM_015946     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-30c-2-3p	PELO
miRBase Accession/Entrez ID	MIMAT0004550	53918
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CGI-17//PRO1770

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-30c-2-3p	rs1262929323 chr6:71376964    A/G rs1413659455 chr6:71376968    T/C rs1421032991 chr6:71376975    C/A rs1421032991 chr6:71376975    C/G rs1488181071 chr6:71376967    G/T rs747913643 chr6:71376976    C/A rs760276048 chr6:71376974    G/C rs775896072 chr6:71376969    A/G

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PELO	chr5:52083850-52083851(+) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr5:52083862-52083863(+) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr5:52083868-52083869(+) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr5:52083903-52083904(+) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr5:52083938-52083939(+) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr5:52084022-52084023(+) m6A 5'UTR//exon       24209618//25456834//24981863//22575960 chr5:52084077-52084078(+) m6A 5'UTR//exon       24209618//25456834//22575960 chr5:52084084-52084085(+) m6A 5'UTR//exon       24209618//25456834//22575960 chr5:52084150-52084151(+) m6A 5'UTR//exon       24209618//25456834 chr5:52095965-52095966(+) m6A 5'UTR//intron       24284625//24981863 chr5:52096029-52096030(+) m6A 5'UTR//intron       24284625//24981863//22575960 chr5:52096121-52096122(+) m6A 5'UTR//intron       24284625//24981863//22575960//22608085 chr5:52096182-52096183(+) m6A 5'UTR//intron       24284625//22575960//22608085 chr5:52096247-52096248(+) m6A CDS//intron       24284625//25456834//24981863//22575960//22608085 chr5:52096259-52096260(+) m6A CDS//intron       24284625//25456834//24981863//22575960//22608085 chr5:52096301-52096302(+) m6A CDS//intron       24284625//25456834//24981863//22575960//22608085 chr5:52096372-52096373(+) m6A CDS//intron       24284625//25456834//24981863//22575960//22608085 chr5:52096483-52096484(+) m6A CDS//intron       24284625//24981863//22575960//22608085 chr5:52096724-52096725(+) m6A CDS//intron       24284625//26404942 chr5:52096788-52096789(+) m6A CDS//intron       24284625//26404942 chr5:52096909-52096910(+) m6A CDS//intron       24284625//22575960//22608085 chr5:52096920-52096921(+) m6A CDS//intron       24284625//22575960//22608085 chr5:52096934-52096935(+) m6A CDS//intron       24284625//24981863//22575960//22608085 chr5:52097259-52097260(+) m6A CDS//exon       24284625//24981863//22575960//22608085 chr5:52097318-52097319(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr5:52097379-52097380(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr5:52097400-52097401(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr5:52097516-52097517(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:52097577-52097578(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:52097631-52097632(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr5:52097682-52097683(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr5:52097695-52097696(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr5:52097714-52097715(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr5:52097832-52097833(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr5:52097844-52097845(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr5:52097851-52097852(+) m6A 3'UTR       24284625//24981863//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-30c-2-3p	Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20)     21505438 Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Serum     24797360 Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Cell line (HEK-293|HeLa)     22984580
	PELO	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleus HeLa-S3 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-30c-2-3p	Gemcitabine 60750 Drug interaction    RC00006870 Eloxatine 5310940 Drug interaction    RC00006871 5-Fluorouracil 3385 Drug interaction    RC00006869

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-30c-2-3p	Cisplatin 5702198       27506865

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-30c-2-3p
Interactor2: PELO

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.