Detail Information

Basic Information:


  VIRBase ID:  

HHID00064878

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30c-2-3p:           AZIN1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30c-2-3p AZIN1
miRBase
Accession/Entrez ID		 MIMAT0004550 51582
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - AZI//AZI1//AZIA1//OAZI//OAZIN//ODC1L

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30c-2-3p
rs1262929323 chr6:71376964    A/G
rs1413659455 chr6:71376968    T/C
rs1421032991 chr6:71376975    C/A
rs1421032991 chr6:71376975    C/G
rs1488181071 chr6:71376967    G/T
rs747913643 chr6:71376976    C/A
rs760276048 chr6:71376974    G/C
rs775896072 chr6:71376969    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR AZIN1
chr8:103845039(-) A-I      intronic
chr8:103844053(-) A-I      intronic
chr8:103844061(-) A-I      intronic
chr8:103865608(-) A-I      intronic
chr8:103844133(-) A-I      intronic
chr8:103842373(-) A-I      intronic
chr8:103842502(-) A-I      intronic
chr8:103842506(-) A-I      intronic
chr8:103842626(-) A-I      intronic
chr8:103843819(-) A-I      intronic
chr8:103843844(-) A-I      intronic
chr8:103844937(-) A-I      intronic
chr8:103851476(-) A-I      intronic
chr8:103852719(-) A-I      intronic
chr8:103863754(-) A-I      intronic
chr8:103863790(-) A-I      intronic
chr8:103863834(-) A-I      intronic
chr8:103863847(-) A-I      intronic
chr8:103864621(-) A-I      intronic
chr8:103864717(-) A-I      intronic
chr8:103865514(-) A-I      intronic
chr8:103865595(-) A-I      intronic
chr8:103865598(-) A-I      intronic
chr8:103865673(-) A-I      intronic
chr8:103866246(-) A-I      intronic
chr8:103866288(-) A-I      intronic
chr8:103866291(-) A-I      intronic
chr8:103866305(-) A-I      intronic
chr8:103866327(-) A-I      intronic
chr8:103866399(-) A-I      intronic
chr8:103866448(-) A-I      intronic
chr8:103867422(-) A-I      intronic
chr8:103867470(-) A-I      intronic
chr8:103867520(-) A-I      intronic
chr8:103867561(-) A-I      intronic
chr8:103873552(-) A-I      intronic
chr8:103873633(-) A-I      intronic
chr8:103873722(-) A-I      intronic
chr8:103873723(-) A-I      intronic
chr8:103874097(-) A-I      intronic
chr8:103874256(-) A-I      intronic
chr8:103867515(-) A-I      intronic
chr8:103844071(-) A-I      intronic
chr8:103842557(-) A-I      intronic
chr8:103844997(-) A-I      intronic
chr8:103863851(-) A-I      intronic
chr8:103863742(-) A-I      intronic
chr8:103863865(-) A-I      intronic
chr8:103863871(-) A-I      intronic
chr8:103842531(-) A-I      intronic
chr8:103871942(-) A-I      intronic
chr8:103867416(-) A-I      intronic
chr8:103866360(-) A-I      intronic
chr8:103842492(-) A-I      intronic
chr8:103852639(-) A-I      intronic
chr8:103865537(-) A-I      intronic
chr8:103845887(-) A-I      intronic
chr8:103845013(-) A-I      intronic
chr8:103863872(-) A-I      intronic
chr8:103873635(-) A-I      intronic
chr8:103874096(-) A-I      intronic
chr8:103866787(-) A-I      intronic
chr8:103866370(-) A-I      intronic
chr8:103855091(-) A-I      intronic
chr8:103843954(-) A-I      intronic
chr8:103845875(-) A-I      intronic
chr8:103866647(-) A-I      intronic
chr8:103843814(-) A-I      intronic
chr8:103854332(-) A-I      intronic
chr8:103867569(-) A-I      intronic
chr8:103873593(-) A-I      intronic
chr8:103864716(-) A-I      intronic
chr8:103859558(-) A-I      intronic
chr8:103845033(-) A-I      intronic
chr8:103852717(-) A-I      intronic
chr8:103866371(-) A-I      intronic
chr8:103865488(-) A-I      intronic
chr8:103866409(-) A-I      intronic
chr8:103866394(-) A-I      intronic
chr8:103842486(-) A-I      intronic
chr8:103842867(-) A-I      intronic
chr8:103866238(-) A-I      intronic
chr8:103859524(-) A-I      intronic
chr8:103873553(-) A-I      intronic
chr8:103865611(-) A-I      intronic
chr8:103865699(-) A-I      intronic
chr8:103873541(-) A-I      intronic
chr8:103855078(-) A-I      intronic
chr8:103873638(-) A-I      intronic
chr8:103867583(-) A-I      intronic
chr8:103874164(-) A-I      intronic
chr8:103865667(-) A-I      intronic
chr8:103866295(-) A-I      intronic
chr8:103865565(-) A-I      intronic
chr8:103844055(-) A-I      intronic
chr8:103865551(-) A-I      intronic
chr8:103842838(-) A-I      intronic
chr8:103866572(-) A-I      intronic
chr8:103863858(-) A-I      intronic
chr8:103865678(-) A-I      intronic
chr8:103845888(-) A-I      intronic
chr8:103865539(-) A-I      intronic
chr8:103863852(-) A-I      intronic
chr8:103859538(-) A-I      intronic
chr8:103874011(-) A-I      intronic
chr8:103845006(-) A-I      intronic
chr8:103866570(-) A-I      intronic
chr8:103849421(-) A-I      intronic
chr8:103844936(-) A-I      intronic
chr8:103859848(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED AZIN1
chr8:103841636(-) A-I exon CDS    19478186   //21960545   //22327324
chr8:103845281(-) A-I intron -    21960545
chr8:103841637(-) A-I exon CDS    21960545
chr8:103859558(-) A-I intron -    21960545
chr8:103842466(-) A-G intron -    22484847
chr8:103842486(-) A-G intron -    22484847
chr8:103842522(-) A-G intron -    22484847
chr8:103842531(-) A-G intron -    22484847
chr8:103842589(-) A-G intron -    22484847
chr8:103842867(-) A-G intron -    22484847
chr8:103844055(-) A-G intron -    22484847
chr8:103845008(-) T-C intron -    22484847
chr8:103845013(-) A-G intron -    22484847
chr8:103845072(-) T-C intron -    22484847
chr8:103849408(-) G-T intron -    22484847
chr8:103851500(-) A-G intron -    22484847
chr8:103852675(-) A-G intron -    22484847
chr8:103852717(-) A-G intron -    22484847
chr8:103854326(-) A-G intron -    22484847
chr8:103854332(-) A-G intron -    22484847
chr8:103855292(-) C-T intron -    22484847
chr8:103859598(-) G-T intron -    22484847
chr8:103863742(-) A-G intron -    22484847
chr8:103863812(-) A-G intron -    22484847
chr8:103863851(-) A-G intron -    22484847
chr8:103863852(-) A-G intron -    22484847
chr8:103863858(-) A-G intron -    22484847
chr8:103863865(-) A-G intron -    22484847
chr8:103863871(-) A-G intron -    22484847
chr8:103863872(-) A-G intron -    22484847
chr8:103864716(-) A-G intron -    22484847
chr8:103864785(-) A-G intron -    22484847
chr8:103865482(-) A-G intron -    22484847
chr8:103865537(-) A-G intron -    22484847
chr8:103865539(-) A-G intron -    22484847
chr8:103865546(-) A-G intron -    22484847
chr8:103865551(-) A-G intron -    22484847
chr8:103865565(-) A-G intron -    22484847
chr8:103865611(-) A-G intron -    22484847
chr8:103865667(-) A-G intron -    22484847
chr8:103865678(-) A-G intron -    22484847
chr8:103865692(-) A-G intron -    22484847
chr8:103865699(-) A-G intron -    22484847
chr8:103866237(-) A-G intron -    22484847
chr8:103866238(-) A-G intron -    22484847
chr8:103866263(-) C-T intron -    22484847
chr8:103866295(-) A-G intron -    22484847
chr8:103866300(-) A-G intron -    22484847
chr8:103866301(-) A-G intron -    22484847
chr8:103866302(-) T-C intron -    22484847
chr8:103866360(-) A-G intron -    22484847
chr8:103866368(-) A-G intron -    22484847
chr8:103866370(-) A-G intron -    22484847
chr8:103866371(-) A-G intron -    22484847
chr8:103866394(-) A-G intron -    22484847
chr8:103866398(-) A-G intron -    22484847
chr8:103866409(-) A-G intron -    22484847
chr8:103866446(-) A-G intron -    22484847
chr8:103866647(-) A-G intron -    22484847
chr8:103873541(-) A-G intron -    22484847
chr8:103873635(-) A-G intron -    22484847
chr8:103873638(-) A-G intron -    22484847
chr8:103874011(-) A-G intron -    22484847
chr8:103874096(-) A-G intron -    22484847
chr8:103874098(-) A-G intron -    22484847
chr8:103874164(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase AZIN1
chr8:103839764-103839765(-) m6A 3'UTR       26404942
chr8:103839842-103839843(-) m6A 3'UTR       24981863
chr8:103846436-103846437(-) m6A CDS       22575960
chr8:103846459-103846460(-) m6A CDS       22575960
chr8:103846468-103846469(-) m6A CDS//exon       22575960
chr8:103848509-103848510(-) m6A CDS//exon       26404942
chr8:103848540-103848541(-) m6A CDS//exon       26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30c-2-3p
Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20)     21505438
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Serum     24797360
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
AZIN1
Chromatin K562 cells     -
Cytosol K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30c-2-3p
Gemcitabine 60750 Drug interaction    RC00006870
Eloxatine 5310940 Drug interaction    RC00006871
5-Fluorouracil 3385 Drug interaction    RC00006869
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30c-2-3p
Cisplatin 5702198       27506865

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30c-2-3p
Interactor2: AZIN1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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