Basic Information:

  VIRBase ID:  

HHID00064868

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30c-2-3p:  MIMAT0004550          BRD1:  NR_146335     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-30c-2-3p	BRD1
miRBase Accession/Entrez ID	MIMAT0004550	23774
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	BRL//BRPF1//BRPF2

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-30c-2-3p	rs1262929323 chr6:71376964    A/G rs1413659455 chr6:71376968    T/C rs1421032991 chr6:71376975    C/A rs1421032991 chr6:71376975    C/G rs1488181071 chr6:71376967    G/T rs747913643 chr6:71376976    C/A rs760276048 chr6:71376974    G/C rs775896072 chr6:71376969    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	BRD1	chr22:50213272(-) A-I      intronic chr22:50214186(-) A-I      intronic chr22:50199703(-) A-I      intronic chr22:50199704(-) A-I      intronic chr22:50199705(-) A-I      intronic chr22:50199711(-) A-I      intronic chr22:50199717(-) A-I      intronic chr22:50199728(-) A-I      intronic chr22:50199730(-) A-I      intronic chr22:50213266(-) A-I      intronic chr22:50213268(-) A-I      intronic chr22:50213274(-) A-I      intronic chr22:50213275(-) A-I      intronic chr22:50213278(-) A-I      intronic chr22:50213294(-) A-I      intronic chr22:50213303(-) A-I      intronic chr22:50213312(-) A-I      intronic chr22:50199739(-) A-I      intronic chr22:50213287(-) A-I      intronic chr22:50213220(-) A-I      intronic chr22:50212714(-) A-I      intronic chr22:50212434(-) A-I      intronic chr22:50212425(-) A-I      intronic chr22:50212386(-) A-I      intronic chr22:50212371(-) A-I      intronic chr22:50212366(-) A-I      intronic chr22:50212354(-) A-I      intronic chr22:50211603(-) A-I      intronic chr22:50211588(-) A-I      intronic chr22:50211580(-) A-I      intronic chr22:50207469(-) A-I      intronic chr22:50207358(-) A-I      intronic chr22:50200527(-) A-I      intronic chr22:50207356(-) A-I      intronic chr22:50214172(-) A-I      intronic chr22:50214171(-) A-I      intronic chr22:50212474(-) A-I      intronic chr22:50213678(-) A-I      intronic chr22:50214167(-) A-I      intronic chr22:50213353(-) A-I      intronic chr22:50213361(-) A-I      intronic chr22:50213598(-) A-I      intronic chr22:50213638(-) A-I      intronic chr22:50207342(-) A-I      intronic chr22:50207463(-) A-I      intronic chr22:50207332(-) A-I      intronic chr22:50207288(-) A-I      intronic chr22:50207142(-) A-I      intronic chr22:50207075(-) A-I      intronic chr22:50207066(-) A-I      intronic chr22:50207040(-) A-I      intronic chr22:50207039(-) A-I      intronic chr22:50206993(-) A-I      intronic chr22:50206932(-) A-I      intronic chr22:50200584(-) A-I      intronic chr22:50213317(-) A-I      intronic chr22:50213291(-) A-I      intronic chr22:50199723(-) A-I      intronic chr22:50207224(-) A-I      intronic chr22:50213364(-) A-I      intronic chr22:50216039(-) A-I      intronic chr22:50212869(-) A-I      intronic chr22:50199583(-) A-I      intronic chr22:50199784(-) A-I      intronic chr22:50180727(-) A-I      intronic chr22:50206966(-) A-I      intronic chr22:50213378(-) A-I      intronic chr22:50200551(-) A-I      intronic chr22:50211595(-) A-I      intronic chr22:50213267(-) A-I      intronic chr22:50199567(-) A-I      intronic chr22:50215823(-) A-I      intronic chr22:50207016(-) A-I      intronic chr22:50212995(-) A-I      intronic chr22:50207065(-) A-I      intronic chr22:50216311(-) A-I      intronic chr22:50213533(-) A-I      intronic chr22:50207371(-) A-I      intronic chr22:50198331(-) A-I      intronic chr22:50200546(-) A-I      intronic chr22:50207218(-) A-I      intronic chr22:50213776(-) A-I      intronic chr22:50215278(-) A-I      intronic chr22:50199462(-) A-I      intronic chr22:50212649(-) A-I      intronic chr22:50213163(-) A-I      intronic chr22:50212703(-) A-I      intronic chr22:50199569(-) A-I      intronic chr22:50180660(-) A-I      intronic chr22:50207238(-) A-I      intronic chr22:50216322(-) A-I      intronic chr22:50212412(-) A-I      intronic chr22:50200563(-) A-I      intronic chr22:50214129(-) A-I      intronic chr22:50211574(-) A-I      intronic chr22:50207314(-) A-I      intronic chr22:50199632(-) A-I      intronic chr22:50213326(-) A-I      intronic chr22:50213236(-) A-I      intronic chr22:50199515(-) A-I      intronic chr22:50209028(-) A-I      intronic chr22:50213259(-) A-I      intronic chr22:50213210(-) A-I      intronic chr22:50216325(-) A-I      intronic chr22:50212996(-) A-I      intronic chr22:50210329(-) A-I      intronic chr22:50211556(-) A-I      intronic chr22:50198305(-) A-I      intronic chr22:50180598(-) A-I      intronic chr22:50207420(-) A-I      intronic chr22:50199734(-) A-I      intronic chr22:50213141(-) A-I      intronic chr22:50207010(-) A-I      intronic chr22:50199479(-) A-I      intronic chr22:50199455(-) A-I      intronic chr22:50212292(-) A-I      intronic chr22:50214221(-) A-I      intronic chr22:50210377(-) A-I      intronic chr22:50207367(-) A-I      intronic chr22:50212368(-) A-I      intronic chr22:50212773(-) A-I      intronic chr22:50213656(-) A-I      intronic chr22:50199798(-) A-I      intronic chr22:50207431(-) A-I      intronic chr22:50207098(-) A-I      intronic chr22:50198314(-) A-I      intronic chr22:50207317(-) A-I      intronic chr22:50213231(-) A-I      intronic chr22:50206955(-) A-I      intronic chr22:50213524(-) A-I      intronic chr22:50180642(-) A-I      intronic chr22:50211492(-) A-I      intronic chr22:50211551(-) A-I      intronic chr22:50213695(-) A-I      intronic chr22:50212983(-) A-I      intronic chr22:50214176(-) A-I      intronic chr22:50216356(-) A-I      intronic chr22:50213612(-) A-I      intronic chr22:50213079(-) A-I      intronic chr22:50215319(-) A-I      intronic chr22:50213223(-) A-I      intronic chr22:50205849(-) A-I      intronic chr22:50199568(-) A-I      intronic chr22:50209882(-) A-I      intronic chr22:50212808(-) A-I      intronic chr22:50207036(-) A-I      intronic chr22:50213106(-) A-I      intronic chr22:50200480(-) A-I      intronic chr22:50200607(-) A-I      intronic chr22:50199554(-) A-I      intronic chr22:50199790(-) A-I      intronic chr22:50180630(-) A-I      intronic chr22:50180576(-) A-I      intronic chr22:50207237(-) A-I      intronic chr22:50213339(-) A-I      intronic chr22:50199789(-) A-I      intronic chr22:50199486(-) A-I      intronic chr22:50207121(-) A-I      intronic chr22:50209876(-) A-I      intronic chr22:50213331(-) A-I      intronic chr22:50213277(-) A-I      intronic chr22:50198377(-) A-I      intronic chr22:50206217(-) A-I      intronic chr22:50200483(-) A-I      intronic chr22:50213302(-) A-I      intronic chr22:50213073(-) A-I      intronic chr22:50213521(-) A-I      intronic chr22:50213534(-) A-I      intronic chr22:50212786(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	BRD1	chr22:50206167(-) A-I intron -    15342557 chr22:50206847(-) A-I intron -    15342557 chr22:50206859(-) A-I intron -    15342557 chr22:50206955(-) A-I intron -    15342557 chr22:50207000(-) A-I intron -    15342557 chr22:50207010(-) A-I intron -    15342557 chr22:50207016(-) A-I intron -    15342557 chr22:50207036(-) A-I intron -    15342557 chr22:50207065(-) A-I intron -    15342557 chr22:50207098(-) A-I intron -    15342557 chr22:50207121(-) A-I intron -    15342557 chr22:50207218(-) A-I intron -    15342557 chr22:50207224(-) A-I intron -    15342557 chr22:50207236(-) A-I intron -    15342557 chr22:50207314(-) A-I intron -    15342557 chr22:50207317(-) A-I intron -    15342557 chr22:50207367(-) A-I intron -    15342557 chr22:50209882(-) A-I intron -    15342557 chr22:50210313(-) A-I intron -    15342557 chr22:50210375(-) A-I intron -    15342557

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	BRD1	chr22:50167078-50167079(-) m6A 3'UTR       27773535 chr22:50167098-50167099(-) m6A 3'UTR       27773535 chr22:50167409-50167410(-) m6A 3'UTR       27773535 chr22:50167601-50167602(-) m6A 3'UTR       27773535 chr22:50169293-50169294(-) m6A 3'UTR//CDS//exon       27371828 chr22:50169314-50169315(-) Am 3'UTR//CDS//exon       - chr22:50181081-50181082(-) m6A CDS       24284625//25456834//27371828//27773536 chr22:50181124-50181125(-) m6A CDS       24284625//25456834//27371828//27773536 chr22:50181157-50181158(-) m6A CDS//intron       24284625//25456834//27371828 chr22:50181163-50181164(-) m6A CDS//intron       24284625//25456834//27371828 chr22:50181190-50181191(-) m6A CDS//intron       25456834//27371828 chr22:50181198-50181199(-) m6A CDS//intron       25456834//27371828 chr22:50181261-50181262(-) m6A CDS//intron       24981863 chr22:50181416-50181417(-) m6A CDS//intron       24981863//27773535 chr22:50181437-50181438(-) m6A CDS//intron       24981863//27773535 chr22:50181446-50181447(-) m6A CDS//intron       24284625//24981863//27773535 chr22:50181461-50181462(-) m6A CDS//intron       24284625//24981863//27773535 chr22:50181472-50181473(-) m6A CDS//intron       24284625//24981863//27773535 chr22:50181480-50181481(-) m6A CDS//intron       24284625//24981863//27773535 chr22:50181509-50181510(-) m6A CDS//intron       24284625//24981863//27773535//27371828 chr22:50181515-50181516(-) m6A CDS//intron       24284625//24981863//27773535//27371828 chr22:50187782-50187783(-) m6A CDS       27371828 chr22:50187872-50187873(-) m6A CDS       27371828//27773536 chr22:50187926-50187927(-) m6A CDS       27371828//27773536//22608085 chr22:50187938-50187939(-) m6A CDS       27371828//27773536//22608085 chr22:50191538-50191539(-) m6A CDS       24981863//27371828//27773536//22608085 chr22:50191616-50191617(-) m6A CDS       24981863//26404942//27773535 chr22:50191682-50191683(-) m6A CDS       24284625//24981863//26404942//27773535 chr22:50191727-50191728(-) m6A CDS       24284625//24981863//26404942//27773535 chr22:50191738-50191739(-) m6A CDS       24284625//26404942 chr22:50214613-50214614(-) m6A exon//intron       27773535 chr22:50216821-50216822(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr22:50216858-50216859(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr22:50216931-50216932(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr22:50216993-50216994(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr22:50217015-50217016(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr22:50217115-50217116(-) m6A CDS       24284625//24981863//27371828//27773536//22575960//22608085 chr22:50217285-50217286(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr22:50217363-50217364(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr22:50217393-50217394(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22575960//22608085 chr22:50217480-50217481(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr22:50217513-50217514(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr22:50217518-50217519(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr22:50217684-50217685(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960//22608085 chr22:50217700-50217701(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960//22608085 chr22:50217729-50217730(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960//22608085 chr22:50217896-50217897(-) m6A CDS       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-30c-2-3p	Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20)     21505438 Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Serum     24797360 Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Cell line (HEK-293|HeLa)     22984580
	BRD1	Chromatin K562 cells     - Cytosol K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-30c-2-3p	Gemcitabine 60750 Drug interaction    RC00006870 Eloxatine 5310940 Drug interaction    RC00006871 5-Fluorouracil 3385 Drug interaction    RC00006869

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-30c-2-3p	Cisplatin 5702198       27506865

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-30c-2-3p
Interactor2: BRD1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.