Basic Information:

  VIRBase ID:  

HHID00064866

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30c-2-3p:  MIMAT0004550          WDR7:  NM_015285     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-30c-2-3p	WDR7
miRBase Accession/Entrez ID	MIMAT0004550	23335
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	TRAG

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-30c-2-3p	rs1262929323 chr6:71376964    A/G rs1413659455 chr6:71376968    T/C rs1421032991 chr6:71376975    C/A rs1421032991 chr6:71376975    C/G rs1488181071 chr6:71376967    G/T rs747913643 chr6:71376976    C/A rs760276048 chr6:71376974    G/C rs775896072 chr6:71376969    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	WDR7	chr18:54324631(+) A-I      intronic chr18:54324656(+) A-I      intronic chr18:54356609(+) A-I      intronic chr18:54324627(+) A-I      intronic chr18:54356647(+) A-I      intronic chr18:54324619(+) A-I      intronic chr18:54324614(+) A-I      intronic chr18:54356675(+) A-I      intronic chr18:54356617(+) A-I      intronic chr18:54356672(+) A-I      intronic chr18:54570840(+) A-I      intronic chr18:54550284(+) A-I      intronic chr18:54550269(+) A-I      intronic chr18:54548950(+) A-I      intronic chr18:54485178(+) A-I      intronic chr18:54485173(+) A-I      intronic chr18:54485162(+) A-I      intronic chr18:54485131(+) A-I      intronic chr18:54485115(+) A-I      intronic chr18:54485105(+) A-I      intronic chr18:54485102(+) A-I      intronic chr18:54484996(+) A-I      intronic chr18:54484399(+) A-I      intronic chr18:54484397(+) A-I      intronic chr18:54484392(+) A-I      intronic chr18:54484390(+) A-I      intronic chr18:54484366(+) A-I      intronic chr18:54453756(+) A-I      intronic chr18:54453507(+) A-I      intronic chr18:54320714(+) A-I      intronic chr18:54323614(+) A-I      intronic chr18:54338749(+) A-I      intronic chr18:54340881(+) A-I      intronic chr18:54447871(+) A-I      intronic chr18:54436632(+) A-I      intronic chr18:54340909(+) A-I      intronic chr18:54436617(+) A-I      intronic chr18:54436616(+) A-I      intronic chr18:54428334(+) A-I      intronic chr18:54425043(+) A-I      intronic chr18:54320681(+) A-I      intronic chr18:54425040(+) A-I      intronic chr18:54425037(+) A-I      intronic chr18:54424974(+) A-I      intronic chr18:54381842(+) A-I      intronic chr18:54354889(+) A-I      intronic chr18:54354908(+) A-I      intronic chr18:54354997(+) A-I      intronic chr18:54355111(+) A-I      intronic chr18:54372264(+) A-I      intronic chr18:54372326(+) A-I      intronic chr18:54381775(+) A-I      intronic chr18:54381724(+) A-I      intronic chr18:54376153(+) A-I      intronic chr18:54372338(+) A-I      intronic chr18:54374311(+) A-I      intronic chr18:54374353(+) A-I      intronic chr18:54374373(+) A-I      intronic chr18:54375916(+) A-I      intronic chr18:54376080(+) A-I      intronic chr18:54376100(+) A-I      intronic chr18:54376037(+) A-I      intronic chr18:54658562(+) A-I      intronic chr18:54641719(+) A-I      intronic chr18:54381793(+) A-I      intronic chr18:54641627(+) A-I      intronic chr18:54345894(+) A-I      intronic chr18:54580294(+) A-I      intronic chr18:54381854(+) A-I      intronic chr18:54333617(+) A-I      intronic chr18:54382883(+) A-I      intronic chr18:54375989(+) A-I      intronic chr18:54374312(+) A-I      intronic chr18:54485142(+) A-I      intronic chr18:54381928(+) A-I      intronic chr18:54681781(+) A-I      intronic chr18:54374329(+) A-I      intronic chr18:54376047(+) A-I      intronic chr18:54357952(+) A-I      intronic chr18:54372299(+) A-I      intronic chr18:54484429(+) A-I      intronic chr18:54321463(+) A-I      intronic chr18:54681765(+) A-I      intronic chr18:54508597(+) A-I      intronic chr18:54425089(+) A-I      intronic chr18:54485076(+) A-I      intronic chr18:54438744(+) A-I      intronic chr18:54453666(+) A-I      intronic chr18:54485079(+) A-I      intronic chr18:54642292(+) A-I      intronic chr18:54439255(+) A-I      intronic chr18:54549085(+) A-I      intronic chr18:54381919(+) A-I      intronic chr18:54381756(+) A-I      intronic chr18:54428371(+) A-I      intronic chr18:54524735(+) A-I      intronic chr18:54375448(+) A-I      intronic chr18:54438724(+) A-I      intronic chr18:54371558(+) A-I      intronic chr18:54642291(+) A-I      intronic chr18:54374351(+) A-I      intronic chr18:54668187(+) A-I      intronic chr18:54438706(+) A-I      intronic chr18:54642209(+) A-I      intronic chr18:54428305(+) A-I      intronic chr18:54376083(+) A-I      intronic chr18:54496333(+) A-I      intronic chr18:54372332(+) A-I      intronic chr18:54356517(+) A-I      intronic chr18:54375545(+) A-I      intronic chr18:54374341(+) A-I      intronic chr18:54322695(+) A-I      intronic chr18:54548946(+) A-I      intronic chr18:54321421(+) A-I      intronic chr18:54381850(+) A-I      intronic chr18:54375316(+) A-I      intronic chr18:54323611(+) A-I      intronic chr18:54322704(+) A-I      intronic chr18:54552860(+) A-I      intronic chr18:54661299(+) A-I      intronic chr18:54425102(+) A-I      intronic chr18:54508641(+) A-I      intronic chr18:54484465(+) A-I      intronic chr18:54376010(+) A-I      intronic chr18:54661363(+) A-I      intronic chr18:54354991(+) A-I      intronic chr18:54549004(+) A-I      intronic chr18:54548991(+) A-I      intronic chr18:54642293(+) A-I      intronic chr18:54631746(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	WDR7	chr18:54398786-54398787(+) m6A CDS//exon//intron       22608085 chr18:54423864-54423865(+) m6A CDS//exon//intron       24981863//22608085 chr18:54423877-54423878(+) m6A CDS//exon//intron       24981863//22608085 chr18:54423883-54423884(+) m6A CDS//exon//intron       24981863//22608085 chr18:54424006-54424007(+) m6A CDS//exon//intron       24284625//24209618//24981863//22608085 chr18:54424081-54424082(+) m6A CDS//exon//intron       24284625//24209618//24981863//22608085 chr18:54424091-54424092(+) m6A CDS//exon//intron       24284625//24209618//24981863//22608085 chr18:54424216-54424217(+) m6A CDS//exon//intron       24284625//24981863//22608085 chr18:54424307-54424308(+) m6A CDS//exon//intron       24284625//24981863//22608085 chr18:54424394-54424395(+) m6A CDS//exon//intron       24284625//24209618//24981863//22608085 chr18:54424410-54424411(+) m6A CDS//exon//intron       24284625//24209618//24981863//22608085 chr18:54424458-54424459(+) m6A CDS//exon//intron       24981863//22608085 chr18:54591306-54591307(+) m6A CDS//exon//intron       - chr18:54591327-54591328(+) m6A CDS//exon//intron       - chr18:54603102-54603103(+) m6A CDS//exon//intron       - chr18:54603424-54603425(+) m6A CDS//intron       24981863 chr18:54605771-54605772(+) m6A CDS//exon//intron       24981863 chr18:54694375-54694376(+) m6A CDS       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-30c-2-3p	Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20)     21505438 Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Serum     24797360 Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Cell line (HEK-293|HeLa)     22984580
	WDR7	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-30c-2-3p	Gemcitabine 60750 Drug interaction    RC00006870 Eloxatine 5310940 Drug interaction    RC00006871 5-Fluorouracil 3385 Drug interaction    RC00006869

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-30c-2-3p	Cisplatin 5702198       27506865

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-30c-2-3p
Interactor2: WDR7

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.