Detail Information

Basic Information:


  VIRBase ID:  

HHID00064803

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-148a-5p:           CYP1B1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-148a-5p CYP1B1
miRBase
Accession/Entrez ID		 MIMAT0004549 1545
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ASGD6//CP1B//CYPIB1//GLC3A//P4501B1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-148a-5p
rs1169404442 chr7:25949960    A/G
rs1305387183 chr7:25949963    C/T
rs1340640170 chr7:25949981    T/C
rs1382103906 chr7:25949968    T/C
rs1392050107 chr7:25949964    G/A
rs752022883 chr7:25949961    G/A
rs758401446 chr7:25949962    TC/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CYP1B1
chr2:38330645(-) A-I      intronic
chr2:38334749(-) A-I      intronic
chr2:38334753(-) A-I      intronic
chr2:38330180(-) A-I      intronic
chr2:38330183(-) A-I      intronic
chr2:38330479(-) A-I      intronic
chr2:38330582(-) A-I      intronic
chr2:38331350(-) A-I      intronic
chr2:38334670(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CYP1B1
chr2:38294785-38294786(-) m6A 3'UTR//intron       27773535
chr2:38294860-38294861(-) m6A 3'UTR//intron       27773535
chr2:38294880-38294881(-) m6A 3'UTR//intron       27773535
chr2:38295950-38295951(-) m6A 3'UTR//intron       24981863
chr2:38296006-38296007(-) m6A 3'UTR//intron       24981863
chr2:38296033-38296034(-) m6A 3'UTR//intron       24981863
chr2:38297342-38297343(-) m6A 3'UTR//intron       26404942
chr2:38297397-38297398(-) m6A 3'UTR//intron       26404942
chr2:38297403-38297404(-) m6A 3'UTR//intron       26404942
chr2:38297432-38297433(-) m6A 3'UTR//intron       26404942
chr2:38297448-38297449(-) m6A 3'UTR//intron       26404942
chr2:38297528-38297529(-) m6A 3'UTR//intron       24981863//26404942
chr2:38297541-38297542(-) m6A 3'UTR//intron       24981863//26404942
chr2:38297555-38297556(-) m6A 3'UTR//intron       24981863//26404942
chr2:38297644-38297645(-) m6A 3'UTR//intron       24981863//26404942
chr2:38297875-38297876(-) m6A CDS       24284625//24981863
chr2:38297960-38297961(-) m6A CDS       24284625//25456834//24981863//28052920//27371828//22608085
chr2:38298074-38298075(-) m6A CDS       24284625//25456834//24981863//28052920//26404942//27371828//22575960//22608085
chr2:38298132-38298133(-) m6A CDS//exon       24284625//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr2:38298156-38298157(-) m6A CDS//exon       24284625//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr2:38298180-38298181(-) m6A CDS//exon       24284625//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr2:38298246-38298247(-) m6A CDS//exon       24284625//25456834//24981863//28052920//26404942//27371828//22575960//22608085
chr2:38298396-38298397(-) m6A 5'UTR//CDS//exon       24284625//24981863//27371828//22575960//22608085
chr2:38298436-38298437(-) m6A 5'UTR//CDS//exon       24284625//25456834//24981863//27371828//22608085
chr2:38300741-38300742(-) m6A exon//intron       24284625//24981863//27371828
chr2:38300937-38300938(-) m6A exon//intron       24981863
chr2:38301533-38301534(-) m6A CDS//exon//intron       24284625//25456834//24981863//27371828//22575960//22608085
chr2:38301611-38301612(-) m6A CDS//intron       24284625//25456834//24981863//27371828//22575960//22608085
chr2:38301710-38301711(-) m6A CDS//intron       24284625//25456834//24981863//28052920//26404942//27371828//27773536//22575960//22608085
chr2:38302470-38302471(-) m6A CDS//intron       24284625
chr2:38302490-38302491(-) m6A CDS//intron       24284625
chr2:38302938-38302939(-) m6A 5'UTR//exon//intron       24284625
chr2:38303069-38303070(-) m6A 5'UTR//exon//intron       24284625//25456834//24981863//27371828
chr2:38303175-38303176(-) m6A 5'UTR//exon//intron       24284625//25456834//24981863//27371828
chr2:38303319-38303320(-) m6A 5'UTR//intron       24284625//25456834//27371828
chr2:38336854-38336855(-) m6A 5'UTR       24284625

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-148a-5p
Exosome Peripheral blood     31746410
Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Breast milk     22211110
Exosome Plasma     23663360
Exosome B lymphoblastoid cells|Breast milk|Chronic lymphocytic leukemia cells|Seminal fluid     -
Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
CYP1B1
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-148a-5p
Interactor2: CYP1B1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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