Detail Information

Basic Information:


  VIRBase ID:  

HHID00064765

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-16-2-3p TRAC
miRBase
Accession/Entrez ID		 MIMAT0004518 28755
Organism Homo sapiens Homo sapiens
Category miRNA other
Alias - IMD7//TCRA//TRA//TRCA

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-16-2-3p
rs1341798864 chr3:160404818    A/C
rs373202341 chr3:160404806    C/T
rs768780684 chr3:160404809    T/C
rs768780684 chr3:160404809    T/G
rs746992239 chr3:160404798    C/CA
rs775368833 chr3:160404800    A/G
rs775368833 chr3:160404800    A/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TRAC
chr14:23016455-23016456(+) m6A CDS       26404942
chr14:23016485-23016486(+) m6A CDS       26404942
chr14:23016538-23016539(+) m6A CDS       26404942
chr14:23016581-23016582(+) m6A CDS       26404942
chr14:23016586-23016587(+) m6A CDS       26404942
chr14:23016596-23016597(+) m6A CDS       26404942
chr14:23016611-23016612(+) m6A CDS       26404942
chr14:23016698-23016699(+) m6A CDS       26404942
chr14:23018622-23018623(+) m6A CDS       26404942
chr14:23020858-23020859(+) m6A 3'UTR       26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-16-2-3p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Plasma     23663360
Exosome Blood|Chronic lymphocytic leukemia cells|Tongue tissue     -
Microvesicle Serum     24797360
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-16-2-3p
Interactor2: TRAC

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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