Detail Information

Basic Information:


  VIRBase ID:  

HHID00064736

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-2-3p:           ZNF622:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-16-2-3p ZNF622
miRBase
Accession/Entrez ID		 MIMAT0004518 90441
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ZPR9

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-16-2-3p
rs1341798864 chr3:160404818    A/C
rs373202341 chr3:160404806    C/T
rs768780684 chr3:160404809    T/C
rs768780684 chr3:160404809    T/G
rs746992239 chr3:160404798    C/CA
rs775368833 chr3:160404800    A/G
rs775368833 chr3:160404800    A/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZNF622
chr5:16451632-16451633(-) m6A 3'UTR       24981863//27371828
chr5:16451681-16451682(-) m6A 3'UTR       24981863//27371828//22608085
chr5:16451697-16451698(-) m6A 3'UTR       24981863//27371828//22608085
chr5:16451708-16451709(-) m6A 3'UTR       24981863//27371828//22608085
chr5:16451811-16451812(-) m6A CDS       24981863//27371828
chr5:16451824-16451825(-) m6A CDS       24981863//27371828
chr5:16451868-16451869(-) m6A CDS       -
chr5:16453133-16453134(-) m6A CDS       -
chr5:16463606-16463607(-) m6A CDS       27773535
chr5:16463655-16463656(-) m6A CDS       24284625//24209618//25456834//27773535//27371828//22608085
chr5:16463718-16463719(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22608085
chr5:16465163-16465164(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22608085
chr5:16465184-16465185(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr5:16465209-16465210(-) m1A CDS       26863196
chr5:16465222-16465223(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:16465246-16465247(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:16465259-16465260(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:16465272-16465273(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:16465403-16465404(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr5:16465412-16465413(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr5:16465423-16465424(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr5:16465436-16465437(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr5:16465485-16465486(-) m1A CDS       26863196
chr5:16465523-16465524(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr5:16465622-16465623(-) Y CDS       26075521
chr5:16465697-16465698(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr5:16465724-16465725(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-16-2-3p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Plasma     23663360
Exosome Blood|Chronic lymphocytic leukemia cells|Tongue tissue     -
Microvesicle Serum     24797360
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
ZNF622
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-16-2-3p
Interactor2: ZNF622

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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