Detail Information

Basic Information:


  VIRBase ID:  

HHID00064733

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-2-3p:           SPRYD3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-16-2-3p SPRYD3
miRBase
Accession/Entrez ID		 MIMAT0004518 84926
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-16-2-3p
rs1341798864 chr3:160404818    A/C
rs373202341 chr3:160404806    C/T
rs768780684 chr3:160404809    T/C
rs768780684 chr3:160404809    T/G
rs746992239 chr3:160404798    C/CA
rs775368833 chr3:160404800    A/G
rs775368833 chr3:160404800    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SPRYD3
chr12:53459255(-) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SPRYD3
chr12:53458282-53458283(-) m6A 3'UTR       -
chr12:53458331-53458332(-) m6A 3'UTR       -
chr12:53458336-53458337(-) m6A 3'UTR       -
chr12:53458368-53458369(-) m6A 3'UTR       -
chr12:53458428-53458429(-) m6A 3'UTR       27773535
chr12:53458786-53458787(-) m6A 3'UTR       24284625
chr12:53458968-53458969(-) m6A 3'UTR       27773535
chr12:53459385-53459386(-) m6A 3'UTR//intron       24284625
chr12:53459395-53459396(-) m6A 3'UTR//intron       24284625
chr12:53459600-53459601(-) m6A 3'UTR       24284625
chr12:53460266-53460267(-) m6A CDS       24209618//24981863//27773535//27371828
chr12:53460364-53460365(-) m6A CDS       24209618//24981863//27773535//27371828
chr12:53460376-53460377(-) m6A CDS       24209618//27773535
chr12:53460409-53460410(-) m6A 3'UTR//CDS       24209618
chr12:53460439-53460440(-) m6A 3'UTR//CDS       24209618
chr12:53461475-53461476(-) m6A 3'UTR//CDS       24209618
chr12:53461981-53461982(-) m6A 3'UTR//CDS       24209618
chr12:53462000-53462001(-) Y 3'UTR//CDS       26075521
chr12:53466964-53466965(-) m6A exon//intron       24209618
chr12:53467015-53467016(-) m6A exon//intron       24209618
chr12:53467071-53467072(-) m6A 3'UTR//CDS//exon       24209618

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-16-2-3p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Plasma     23663360
Exosome Blood|Chronic lymphocytic leukemia cells|Tongue tissue     -
Microvesicle Serum     24797360
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
SPRYD3
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-16-2-3p
Interactor2: SPRYD3

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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