Basic Information:

  VIRBase ID:  

HHID00064513

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-2-3p:  MIMAT0004518          S1PR1:  NM_001400     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-16-2-3p	S1PR1
miRBase Accession/Entrez ID	MIMAT0004518	1901
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CD363//CHEDG1//D1S3362//ECGF1//EDG-1//EDG1//S1P1

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-16-2-3p	rs1341798864 chr3:160404818    A/C rs373202341 chr3:160404806    C/T rs768780684 chr3:160404809    T/C rs768780684 chr3:160404809    T/G rs746992239 chr3:160404798    C/CA rs775368833 chr3:160404800    A/G rs775368833 chr3:160404800    A/T

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	S1PR1	chr1:101702480-101702481(+) m6A 5'UTR       - chr1:101702499-101702500(+) m6A 5'UTR//exon       - chr1:101702535-101702536(+) m6A 5'UTR//exon       - chr1:101704658-101704659(+) m6A CDS//exon       22608085 chr1:101704667-101704668(+) m6A CDS//exon       24981863//22608085 chr1:101704677-101704678(+) m6A CDS//exon       24981863//22608085 chr1:101704727-101704728(+) m6A CDS//exon       24981863//22608085 chr1:101704756-101704757(+) m6A CDS//exon       24981863//22608085 chr1:101704811-101704812(+) m6A CDS//exon       24981863//22608085 chr1:101704989-101704990(+) m6A CDS//exon       24981863//22608085 chr1:101705087-101705088(+) m6A CDS       24981863//22608085 chr1:101705227-101705228(+) m6A CDS       24981863 chr1:101705258-101705259(+) m6A CDS       24981863 chr1:101705308-101705309(+) m6A CDS       - chr1:101705395-101705396(+) m6A CDS       - chr1:101705543-101705544(+) m6A CDS       25456834//24981863//22575960//22608085 chr1:101705606-101705607(+) m6A CDS       25456834//24981863//22575960//22608085 chr1:101705639-101705640(+) m6A CDS       25456834//24981863//22575960//22608085 chr1:101705650-101705651(+) m6A CDS       25456834//24981863//22608085 chr1:101705690-101705691(+) m6A 3'UTR       25456834//24981863//22608085 chr1:101705828-101705829(+) m6A 3'UTR       25456834//24981863//22608085 chr1:101705875-101705876(+) m6A 3'UTR       25456834//24981863//22608085 chr1:101706012-101706013(+) m6A 3'UTR       24981863 chr1:101706085-101706086(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-16-2-3p	Exosome Jurkat-derived T cell line (J77cl20)     21505438 Exosome Plasma     23663360 Exosome Blood|Chronic lymphocytic leukemia cells|Tongue tissue     - Microvesicle Serum     24797360 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
	S1PR1	Cytosol HeLa-S3 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-16-2-3p
Interactor2: S1PR1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.