Basic Information:

  VIRBase ID:  

HHID00064460

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-29b-2-5p:  MIMAT0004515          ZFP91:  NM_053023     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-29b-2-5p	ZFP91
miRBase Accession/Entrez ID	MIMAT0004515	80829
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	DMS-8//DSM-8//FKSG11//PZF//ZFP-91//ZNF757

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-29b-2-5p	rs1389711693 chr1:207802500    C/A rs200396959 chr1:207802497    C/T rs971770488 chr1:207802503    T/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ZFP91	chr11:58370431(+) A-I      intronic chr11:58363239(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ZFP91	chr11:58346725-58346726(+) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr11:58346744-58346745(+) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr11:58346780-58346781(+) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr11:58346797-58346798(+) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr11:58346883-58346884(+) m6A CDS       24284625//24209618//25456834//24981863//27371828//22575960//22608085 chr11:58346917-58346918(+) m6A CDS       24209618//25456834//27371828//22575960//22608085 chr11:58377326-58377327(+) m1A CDS       26863196 chr11:58377454-58377455(+) m6A CDS       27773535 chr11:58377486-58377487(+) m6A CDS       24981863//27773535 chr11:58377497-58377498(+) m6A CDS       24981863//27773535 chr11:58378448-58378449(+) m1A CDS       26863196 chr11:58378504-58378505(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr11:58378512-58378513(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr11:58379080-58379081(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr11:58379131-58379132(+) m1A CDS       26863196 chr11:58379199-58379200(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr11:58379759-58379760(+) m1A CDS       26863196 chr11:58380283-58380284(+) m6A CDS       24981863//27773535 chr11:58381805-58381806(+) m6A CDS       27773535 chr11:58384728-58384729(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr11:58384739-58384740(+) m6A CDS       24284625//24981863//26404942//22608085 chr11:58384793-58384794(+) m6A CDS       24284625//24209618//24981863//26404942//22608085 chr11:58384967-58384968(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr11:58385114-58385115(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr11:58385162-58385163(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr11:58385172-58385173(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr11:58385182-58385183(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr11:58385190-58385191(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr11:58385204-58385205(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr11:58385213-58385214(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr11:58385238-58385239(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr11:58385406-58385407(+) m6A 3'UTR       24284625//24209618//24981863 chr11:58385474-58385475(+) m6A 3'UTR       24284625 chr11:58387476-58387477(+) m6A 3'UTR       26404942 chr11:58387597-58387598(+) Y 3'UTR       25219674 chr11:58388334-58388335(+) m6A 3'UTR       27773535 chr11:58388357-58388358(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-29b-2-5p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Skeletal muscle myoblasts     21637849
	ZFP91	Chromatin K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-29b-2-5p
Interactor2: ZFP91

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.