Basic Information:

  VIRBase ID:  

HHID00064410

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-29b-2-5p:  MIMAT0004515          ATP11A:  NM_032189     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-29b-2-5p	ATP11A
miRBase Accession/Entrez ID	MIMAT0004515	23250
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	ATPIH//ATPIS

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-29b-2-5p	rs1389711693 chr1:207802500    C/A rs200396959 chr1:207802497    C/T rs971770488 chr1:207802503    T/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ATP11A	chr13:113505972(+) A-I      intronic chr13:113350989(+) A-I      intronic chr13:113428946(+) A-I      intronic chr13:113448986(+) A-I      intronic chr13:113448912(+) A-I      intronic chr13:113373043(+) A-I      intronic chr13:113402030(+) A-I      intronic chr13:113402942(+) A-I      intronic chr13:113356026(+) A-I      intronic chr13:113402889(+) A-I      intronic chr13:113402869(+) A-I      intronic chr13:113449035(+) A-I      intronic chr13:113402846(+) A-I      intronic chr13:113402841(+) A-I      intronic chr13:113449036(+) A-I      intronic chr13:113402784(+) A-I      intronic chr13:113402780(+) A-I      intronic chr13:113402029(+) A-I      intronic chr13:113503276(+) A-I      intronic chr13:113447726(+) A-I      intronic chr13:113402779(+) A-I      intronic chr13:113402759(+) A-I      intronic chr13:113345647(+) A-I      intronic chr13:113447791(+) A-I      intronic chr13:113402003(+) A-I      intronic chr13:113348256(+) A-I      intronic chr13:113447641(+) A-I      intronic chr13:113447633(+) A-I      intronic chr13:113447681(+) A-I      intronic chr13:113401930(+) A-I      intronic chr13:113392697(+) A-I      intronic chr13:113507430(+) A-I      intronic chr13:113392461(+) A-I      intronic chr13:113451341(+) A-I      intronic chr13:113392457(+) A-I      intronic chr13:113402749(+) A-I      intronic chr13:113507392(+) A-I      intronic chr13:113506058(+) A-I      intronic chr13:113506037(+) A-I      intronic chr13:113447655(+) A-I      intronic chr13:113373078(+) A-I      intronic chr13:113373268(+) A-I      intronic chr13:113402147(+) A-I      intronic chr13:113402061(+) A-I      intronic chr13:113402154(+) A-I      intronic chr13:113507419(+) A-I      intronic chr13:113506057(+) A-I      intronic chr13:113484749(+) A-I      intronic chr13:113431052(+) A-I      intronic chr13:113372215(+) A-I      intronic chr13:113484617(+) A-I      intronic chr13:113468507(+) A-I      intronic chr13:113505965(+) A-I      intronic chr13:113468402(+) A-I      intronic chr13:113353161(+) A-I      intronic chr13:113456539(+) A-I      intronic chr13:113465113(+) A-I      intronic chr13:113451342(+) A-I      intronic chr13:113449114(+) A-I      intronic chr13:113465107(+) A-I      intronic chr13:113447602(+) A-I      intronic chr13:113372342(+) A-I      intronic chr13:113447616(+) A-I      intronic chr13:113431758(+) A-I      intronic chr13:113353175(+) A-I      intronic chr13:113505903(+) A-I      intronic chr13:113447572(+) A-I      intronic chr13:113447540(+) A-I      intronic chr13:113447751(+) A-I      intronic chr13:113507459(+) A-I      intronic chr13:113372322(+) A-I      intronic chr13:113402738(+) A-I      intronic chr13:113449110(+) A-I      intronic chr13:113372296(+) A-I      intronic chr13:113459879(+) A-I      intronic chr13:113402091(+) A-I      intronic chr13:113502307(+) A-I      intronic chr13:113449127(+) A-I      intronic chr13:113435551(+) A-I      intronic chr13:113502144(+) A-I      intronic chr13:113373168(+) A-I      intronic chr13:113402685(+) A-I      intronic chr13:113452714(+) A-I      intronic chr13:113459825(+) A-I      intronic chr13:113449025(+) A-I      intronic chr13:113449071(+) A-I      intronic chr13:113431799(+) A-I      intronic chr13:113459829(+) A-I      intronic chr13:113447682(+) A-I      intronic chr13:113447645(+) A-I      intronic chr13:113431716(+) A-I      intronic chr13:113431713(+) A-I      intronic chr13:113431194(+) A-I      intronic chr13:113431076(+) A-I      intronic chr13:113431056(+) A-I      intronic chr13:113431040(+) A-I      intronic chr13:113431028(+) A-I      intronic chr13:113507320(+) A-I      intronic chr13:113449092(+) A-I      intronic chr13:113431009(+) A-I      intronic chr13:113430933(+) A-I      intronic chr13:113430916(+) A-I      intronic chr13:113430907(+) A-I      intronic chr13:113507494(+) A-I      intronic chr13:113507491(+) A-I      intronic chr13:113505978(+) A-I      intronic chr13:113505936(+) A-I      intronic chr13:113447700(+) A-I      intronic chr13:113465976(+) A-I      intronic chr13:113502138(+) A-I      intronic chr13:113507436(+) A-I      intronic chr13:113505981(+) A-I      intronic chr13:113502294(+) A-I      intronic chr13:113505857(+) A-I      intronic chr13:113507339(+) A-I      intronic chr13:113502167(+) A-I      intronic chr13:113505971(+) A-I      intronic chr13:113447696(+) A-I      intronic chr13:113431003(+) A-I      intronic chr13:113505935(+) A-I      intronic chr13:113449438(+) A-I      intronic chr13:113505905(+) A-I      intronic chr13:113447746(+) A-I      intronic chr13:113506026(+) A-I      intronic chr13:113449032(+) A-I      intronic chr13:113435559(+) A-I      intronic chr13:113505988(+) A-I      intronic chr13:113460008(+) A-I      intronic chr13:113507423(+) A-I      intronic chr13:113507407(+) A-I      intronic chr13:113505929(+) A-I      intronic chr13:113476990(+) A-I      intronic chr13:113431731(+) A-I      intronic chr13:113447536(+) A-I      intronic chr13:113507319(+) A-I      intronic chr13:113505953(+) A-I      intronic chr13:113514452(+) A-I      intronic chr13:113477006(+) A-I      intronic chr13:113460281(+) A-I      intronic chr13:113447779(+) A-I      intronic chr13:113361582(+) A-I      intronic chr13:113459828(+) A-I      intronic chr13:113373124(+) A-I      intronic chr13:113459869(+) A-I      intronic chr13:113449017(+) A-I      intronic chr13:113345622(+) A-I      intronic chr13:113465978(+) A-I      intronic chr13:113431010(+) A-I      intronic chr13:113447688(+) A-I      intronic chr13:113451617(+) A-I      intronic chr13:113505906(+) A-I      intronic chr13:113507387(+) A-I      intronic chr13:113449439(+) A-I      intronic chr13:113449187(+) A-I      intronic chr13:113345619(+) A-I      intronic chr13:113505886(+) A-I      intronic chr13:113507400(+) A-I      intronic chr13:113505969(+) A-I      intronic chr13:113372315(+) A-I      intronic chr13:113373102(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ATP11A	chr13:113465092(+) A-I intron -    21960545 chr13:113465113(+) A-I intron -    21960545 chr13:113502138(+) A-G intron -    22484847 chr13:113505971(+) A-G intron -    22484847 chr13:113505978(+) A-G intron -    22484847 chr13:113505981(+) A-G intron -    22484847 chr13:113506026(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ATP11A	chr13:113344734-113344735(+) m6A CDS       24284625//24209618 chr13:113351157-113351158(+) m6A exon//intron       24284625//24209618 chr13:113351163-113351164(+) m6A exon//intron       24284625//24209618 chr13:113351209-113351210(+) m6A exon//intron       24284625 chr13:113351216-113351217(+) m6A exon//intron       24284625 chr13:113465021-113465022(+) m6A CDS//exon       - chr13:113470403-113470404(+) m6A CDS//exon       24284625 chr13:113470429-113470430(+) m6A CDS//exon       24284625 chr13:113473636-113473637(+) m6A CDS//exon       24284625 chr13:113488931-113488932(+) m6A CDS//exon       - chr13:113488952-113488953(+) m6A CDS//exon       - chr13:113488961-113488962(+) m6A CDS//exon       - chr13:113513680-113513681(+) m6A exon//intron       - chr13:113514712-113514713(+) m6A CDS//exon//intron       24284625 chr13:113514742-113514743(+) m6A CDS//exon//intron       24284625 chr13:113514881-113514882(+) m6A 3'UTR//exon//intron       25456834 chr13:113514948-113514949(+) m6A 3'UTR//exon//intron       25456834 chr13:113530331-113530332(+) m6A exon//intron       24284625 chr13:113532584-113532585(+) m6A 3'UTR//CDS//exon//intron       24284625//24981863 chr13:113532612-113532613(+) m6A 3'UTR//exon//intron       24284625 chr13:113532655-113532656(+) m6A exon//intron       24284625 chr13:113534676-113534677(+) m6A exon//intron       24284625//25456834 chr13:113534737-113534738(+) m6A exon//intron       24284625//25456834 chr13:113534923-113534924(+) m6A CDS//exon//intron       24284625//25456834//22608085 chr13:113535296-113535297(+) m6A exon//intron       - chr13:113535341-113535342(+) m6A exon//intron       - chr13:113535417-113535418(+) m6A exon//intron       - chr13:113535434-113535435(+) m6A exon//intron       - chr13:113535509-113535510(+) m6A exon//intron       - chr13:113536151-113536152(+) m6A 3'UTR//CDS//exon//intron       24284625//25456834//22608085 chr13:113536401-113536402(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr13:113536488-113536489(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr13:113536552-113536553(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr13:113536670-113536671(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr13:113536987-113536988(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr13:113537119-113537120(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr13:113537144-113537145(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr13:113537198-113537199(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr13:113537231-113537232(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr13:113537656-113537657(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr13:113537677-113537678(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr13:113537692-113537693(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr13:113537790-113537791(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr13:113537916-113537917(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr13:113537923-113537924(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr13:113537954-113537955(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr13:113537998-113537999(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr13:113538012-113538013(+) m6A 3'UTR//exon       24284625//24981863//27773535//22608085 chr13:113539193-113539194(+) m6A 3'UTR       24284625 chr13:113539203-113539204(+) m6A 3'UTR       24284625 chr13:113540294-113540295(+) m6A 3'UTR       24284625 chr13:113540336-113540337(+) m6A 3'UTR       24284625//24981863 chr13:113541202-113541203(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-29b-2-5p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Skeletal muscle myoblasts     21637849
	ATP11A	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-29b-2-5p
Interactor2: ATP11A

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.