Detail Information

Basic Information:


  VIRBase ID:  

HHID00064302

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-29b-1-5p:           ARL5B:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-29b-1-5p ARL5B
miRBase
Accession/Entrez ID		 MIMAT0004514 221079
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ARL8

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-29b-1-5p
rs1189550020 chr7:130877522    G/GA
rs1554489373 chr7:130877519    T/C
rs1554489375 chr7:130877520    A/C
rs782109811 chr7:130877509    TA/T
rs778204762 chr7:130877526    C/A
rs778204762 chr7:130877526    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ARL5B
chr10:18952041(+) A-I      intronic
chr10:18959344(+) A-I      intronic
chr10:18951736(+) A-I      intronic
chr10:18959330(+) A-I      intronic
chr10:18959338(+) A-I      intronic
chr10:18952018(+) A-I      intronic
chr10:18959315(+) A-I      intronic
chr10:18960250(+) A-I      intronic
chr10:18962045(+) A-I      intronic
chr10:18960298(+) A-I      intronic
chr10:18952032(+) A-I      intronic
chr10:18959285(+) A-I      intronic
chr10:18959339(+) A-I      intronic
chr10:18959361(+) A-I      intronic
chr10:18960281(+) A-I      intronic
chr10:18960290(+) A-I      intronic
chr10:18960333(+) A-I      intronic
chr10:18960698(+) A-I      intronic
chr10:18958801(+) A-I      intronic
chr10:18954184(+) A-I      intronic
chr10:18960801(+) A-I      intronic
chr10:18960791(+) A-I      intronic
chr10:18959301(+) A-I      intronic
chr10:18957824(+) A-I      intronic
chr10:18960323(+) A-I      intronic
chr10:18954126(+) A-I      intronic
chr10:18960372(+) A-I      intronic
chr10:18957799(+) A-I      intronic
chr10:18957959(+) A-I      intronic
chr10:18958763(+) A-I      intronic
chr10:18958765(+) A-I      intronic
chr10:18958906(+) A-I      intronic
chr10:18958908(+) A-I      intronic
chr10:18954246(+) A-I      intronic
chr10:18954142(+) A-I      intronic
chr10:18959452(+) A-I      intronic
chr10:18954249(+) A-I      intronic
chr10:18960355(+) A-I      intronic
chr10:18954127(+) A-I      intronic
chr10:18962263(+) A-I      intronic
chr10:18958843(+) A-I      intronic
chr10:18957972(+) A-I      intronic
chr10:18958775(+) A-I      intronic
chr10:18957747(+) A-I      intronic
chr10:18957865(+) A-I      intronic
chr10:18958769(+) A-I      intronic
chr10:18954175(+) A-I      intronic
chr10:18960203(+) A-I      intronic
chr10:18959378(+) A-I      intronic
chr10:18960795(+) A-I      intronic
chr10:18960219(+) A-I      intronic
chr10:18958667(+) A-I      intronic
chr10:18954245(+) A-I      intronic
chr10:18958772(+) A-I      intronic
chr10:18960360(+) A-I      intronic
chr10:18957873(+) A-I      intronic
chr10:18962095(+) A-I      intronic
chr10:18958768(+) A-I      intronic
chr10:18958666(+) A-I      intronic
chr10:18958644(+) A-I      intronic
chr10:18958816(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ARL5B
chr10:18957972(+) A-I intron -    22327324
chr10:18957972(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ARL5B
chr10:18948337-18948338(+) m6A 5'UTR       24981863
chr10:18948371-18948372(+) m6A 5'UTR       24981863
chr10:18948509-18948510(+) m6A 5'UTR       24209618
chr10:18948539-18948540(+) m6A 5'UTR       24209618
chr10:18964163-18964164(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22608085
chr10:18964189-18964190(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22608085
chr10:18964251-18964252(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22608085
chr10:18964287-18964288(+) m6A 3'UTR       24284625//24981863//26404942//22608085
chr10:18964293-18964294(+) m6A 3'UTR       24284625//24981863//26404942//22608085
chr10:18964550-18964551(+) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr10:18964571-18964572(+) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr10:18964608-18964609(+) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr10:18964624-18964625(+) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr10:18964629-18964630(+) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr10:18968596-18968597(+) m6A 3'UTR       24981863
chr10:18968633-18968634(+) m6A 3'UTR       24981863//26404942
chr10:18968677-18968678(+) m6A 3'UTR       26404942
chr10:18968704-18968705(+) m6A 3'UTR       26404942
chr10:18970122-18970123(+) m6A 3'UTR       24981863//26404942
chr10:18970135-18970136(+) m6A 3'UTR       24981863//26404942
chr10:18970146-18970147(+) m6A 3'UTR       24981863//26404942
chr10:18970205-18970206(+) m6A 3'UTR       24981863//26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-29b-1-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
ARL5B
Chromatin K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-29b-1-5p
Interactor2: ARL5B

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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