Detail Information

Basic Information:


  VIRBase ID:  

HHID00064300

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-29b-1-5p:           MPZL3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-29b-1-5p MPZL3
miRBase
Accession/Entrez ID		 MIMAT0004514 196264
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-29b-1-5p
rs1189550020 chr7:130877522    G/GA
rs1554489373 chr7:130877519    T/C
rs1554489375 chr7:130877520    A/C
rs782109811 chr7:130877509    TA/T
rs778204762 chr7:130877526    C/A
rs778204762 chr7:130877526    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MPZL3
chr11:118118858(-) A-I      intronic
chr11:118114469(-) A-I      intronic
chr11:118114481(-) A-I      intronic
chr11:118114359(-) A-I      intronic
chr11:118117595(-) A-I      intronic
chr11:118114301(-) A-I      intronic
chr11:118118412(-) A-I      intronic
chr11:118104626(-) A-I      intronic
chr11:118114321(-) A-I      intronic
chr11:118117500(-) A-I      intronic
chr11:118117464(-) A-I      intronic
chr11:118117544(-) A-I      intronic
chr11:118115744(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED MPZL3
chr11:118120911(-) C-A intron -    22484847
chr11:118120913(-) T-A intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MPZL3
chr11:118097425-118097426(-) m6A 3'UTR       27773535
chr11:118097600-118097601(-) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr11:118097626-118097627(-) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr11:118097632-118097633(-) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr11:118097647-118097648(-) m6A 3'UTR       24981863//26404942//27773535//22608085
chr11:118097658-118097659(-) m6A 3'UTR       24981863//26404942//27773535//22608085
chr11:118100398-118100399(-) m6A 3'UTR       24981863//27773535
chr11:118100411-118100412(-) m6A 3'UTR       24981863//27773535
chr11:118100422-118100423(-) m6A 3'UTR       24981863//27773535
chr11:118100463-118100464(-) m6A 3'UTR       24981863//27773535//27371828
chr11:118100472-118100473(-) m6A 3'UTR       24981863//27773535//27371828
chr11:118100497-118100498(-) m6A 3'UTR       24981863//27773535//27371828
chr11:118100510-118100511(-) m6A 3'UTR       24981863//27773535//27371828
chr11:118100564-118100565(-) m6A 3'UTR       27773535//27371828
chr11:118100571-118100572(-) m6A 3'UTR       27773535
chr11:118110960-118110961(-) m6A CDS//intron       -
chr11:118110965-118110966(-) m6A CDS//intron       -
chr11:118110976-118110977(-) m6A CDS//intron       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-29b-1-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
MPZL3
Exosome Blood     -
Nucleoplasm K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-29b-1-5p
Interactor2: MPZL3

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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