Basic Information:

  VIRBase ID:  

HHID00064297

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-29b-1-5p:  MIMAT0004514          DGKH:  NM_001204504     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-29b-1-5p	DGKH
miRBase Accession/Entrez ID	MIMAT0004514	160851
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	DGKeta

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-29b-1-5p	rs1189550020 chr7:130877522    G/GA rs1554489373 chr7:130877519    T/C rs1554489375 chr7:130877520    A/C rs782109811 chr7:130877509    TA/T rs778204762 chr7:130877526    C/A rs778204762 chr7:130877526    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DGKH	chr13:42797825(+) A-I      intronic chr13:42638025(+) A-I      intronic chr13:42799248(+) A-I      intronic chr13:42627263(+) A-I      intronic chr13:42730525(+) A-I      intronic chr13:42618071(+) A-I      intronic chr13:42667121(+) A-I      intronic chr13:42624918(+) A-I      intronic chr13:42625986(+) A-I      intronic chr13:42744474(+) A-I      intronic chr13:42799116(+) A-I      intronic chr13:42723303(+) A-I      intronic chr13:42667300(+) A-I      intronic chr13:42667308(+) A-I      intronic chr13:42624913(+) A-I      intronic chr13:42680273(+) A-I      intronic chr13:42745029(+) A-I      intronic chr13:42723300(+) A-I      intronic chr13:42791568(+) A-I      intronic chr13:42799077(+) A-I      intronic chr13:42792825(+) A-I      intronic chr13:42792150(+) A-I      intronic chr13:42792051(+) A-I      intronic chr13:42791653(+) A-I      intronic chr13:42791559(+) A-I      intronic chr13:42747296(+) A-I      intronic chr13:42747237(+) A-I      intronic chr13:42747201(+) A-I      intronic chr13:42747169(+) A-I      intronic chr13:42730536(+) A-I      intronic chr13:42730528(+) A-I      intronic chr13:42730496(+) A-I      intronic chr13:42706806(+) A-I      intronic chr13:42723232(+) A-I      intronic chr13:42723231(+) A-I      intronic chr13:42723213(+) A-I      intronic chr13:42723150(+) A-I      intronic chr13:42723148(+) A-I      intronic chr13:42680283(+) A-I      intronic chr13:42680279(+) A-I      intronic chr13:42667237(+) A-I      intronic chr13:42660237(+) A-I      intronic chr13:42660088(+) A-I      intronic chr13:42640315(+) A-I      intronic chr13:42640216(+) A-I      intronic chr13:42640137(+) A-I      intronic chr13:42640114(+) A-I      intronic chr13:42638063(+) A-I      intronic chr13:42638040(+) A-I      intronic chr13:42799655(+) A-I      intronic chr13:42638032(+) A-I      intronic chr13:42633621(+) A-I      intronic chr13:42633614(+) A-I      intronic chr13:42633486(+) A-I      intronic chr13:42799157(+) A-I      intronic chr13:42667155(+) A-I      intronic chr13:42771284(+) A-I      intronic chr13:42706883(+) A-I      intronic chr13:42791434(+) A-I      intronic chr13:42761775(+) A-I      intronic chr13:42666244(+) A-I      intronic chr13:42797776(+) A-I      intronic chr13:42792098(+) A-I      intronic chr13:42753301(+) A-I      intronic chr13:42736515(+) A-I      intronic chr13:42746445(+) A-I      intronic chr13:42706885(+) A-I      intronic chr13:42753309(+) A-I      intronic chr13:42680344(+) A-I      intronic chr13:42755173(+) A-I      intronic chr13:42797643(+) A-I      intronic chr13:42730491(+) A-I      intronic chr13:42640225(+) A-I      intronic chr13:42625919(+) A-I      intronic chr13:42640173(+) A-I      intronic chr13:42792109(+) A-I      intronic chr13:42707572(+) A-I      intronic chr13:42792103(+) A-I      intronic chr13:42624939(+) A-I      intronic chr13:42753249(+) A-I      intronic chr13:42680244(+) A-I      intronic chr13:42723267(+) A-I      intronic chr13:42720627(+) A-I      intronic chr13:42799633(+) A-I      intronic chr13:42624392(+) A-I      intronic chr13:42708976(+) A-I      intronic chr13:42730518(+) A-I      intronic chr13:42799242(+) A-I      intronic chr13:42637982(+) A-I      intronic chr13:42681125(+) A-I      intronic chr13:42660155(+) A-I      intronic chr13:42725584(+) A-I      intronic chr13:42791999(+) A-I      intronic chr13:42791461(+) A-I      intronic chr13:42618246(+) A-I      intronic chr13:42799191(+) A-I      intronic chr13:42720624(+) A-I      intronic chr13:42746431(+) A-I      intronic chr13:42791622(+) A-I      intronic chr13:42660238(+) A-I      intronic chr13:42797774(+) A-I      intronic chr13:42799656(+) A-I      intronic chr13:42791960(+) A-I      intronic chr13:42680261(+) A-I      intronic chr13:42791477(+) A-I      intronic chr13:42791476(+) A-I      intronic chr13:42792050(+) A-I      intronic chr13:42753686(+) A-I      intronic chr13:42706884(+) A-I      intronic chr13:42624297(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	DGKH	chr13:42644496(+) A-I intron -    22327324 chr13:42618246(+) A-I intron -    22327324 chr13:42619395(+) A-I intron -    22327324 chr13:42720624(+) A-G intron -    22484847 chr13:42725584(+) A-G intron -    22484847 chr13:42619196(+) A-G intron -    22484847 chr13:42619213(+) A-G intron -    22484847 chr13:42667119(+) C-T intron -    22484847 chr13:42730491(+) A-G intron -    22484847 chr13:42730518(+) A-G intron -    22484847 chr13:42791622(+) A-G intron -    22484847 chr13:42799191(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DGKH	chr13:42623049-42623050(+) m6A CDS       24209618 chr13:42623058-42623059(+) m6A CDS       24209618 chr13:42623095-42623096(+) m6A CDS       24209618 chr13:42701615-42701616(+) m6A CDS       - chr13:42729466-42729467(+) m6A CDS//exon       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-29b-1-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Skeletal muscle myoblasts     21637849
	DGKH	Chromatin K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-29b-1-5p
Interactor2: DGKH

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.