Detail Information

Basic Information:


  VIRBase ID:  

HHID00063975

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-99a-3p:           SLC46A3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-99a-3p SLC46A3
miRBase
Accession/Entrez ID		 MIMAT0004511 283537
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - FKSG16

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-99a-3p
rs1214222916 chr21:16539147    T/C
rs1419616925 chr21:16539158    T/A
rs763134262 chr21:16539151    A/G
rs766428664 chr21:16539153    G/A
rs774748688 chr21:16539159    G/C
rs950382507 chr21:16539154    G/A
rs1271070422 chr21:16539142    C/T
rs913397001 chr21:16539145    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SLC46A3
chr13:29282835(-) A-I      intronic
chr13:29277766(-) A-I      intronic
chr13:29282825(-) A-I      intronic
chr13:29282848(-) A-I      intronic
chr13:29282877(-) A-I      intronic
chr13:29282887(-) A-I      intronic
chr13:29282893(-) A-I      intronic
chr13:29282462(-) A-I      intronic
chr13:29282532(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SLC46A3
chr13:29288647(-) C-T intron -    21725310

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SLC46A3
chr13:29274265-29274266(-) m6A 3'UTR//exon       27773535
chr13:29274422-29274423(-) m6A 3'UTR//exon       27773535
chr13:29274442-29274443(-) m6A 3'UTR//exon       27773535
chr13:29274516-29274517(-) m6A 3'UTR//exon       27773535
chr13:29275488-29275489(-) m6A 3'UTR//exon//intron       24981863//27773535//22608085
chr13:29275500-29275501(-) m6A 3'UTR//exon//intron       24981863//27773535//22608085
chr13:29275505-29275506(-) m6A 3'UTR//exon//intron       24981863//27773535//22608085
chr13:29275532-29275533(-) m6A 3'UTR//exon//intron       24981863//27773535//22608085
chr13:29275569-29275570(-) m6A 3'UTR//exon//intron       24981863//27773535//22608085
chr13:29275621-29275622(-) m6A 3'UTR//exon//intron       24981863//22608085
chr13:29275640-29275641(-) m6A CDS//exon       24981863//22608085
chr13:29275678-29275679(-) m6A CDS//exon       24981863
chr13:29287324-29287325(-) m6A CDS       24981863//22608085
chr13:29287333-29287334(-) m6A CDS       24981863//22608085
chr13:29287345-29287346(-) m6A CDS       24981863//22608085
chr13:29287380-29287381(-) m6A CDS       24981863//22608085
chr13:29287387-29287388(-) m6A CDS       24981863//22608085
chr13:29287393-29287394(-) m6A CDS       24981863//22608085
chr13:29292854-29292855(-) m6A 5'UTR       24981863
chr13:29292920-29292921(-) m6A 5'UTR       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-99a-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
SLC46A3
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-99a-3p
Interactor2: SLC46A3

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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