Basic Information:

  VIRBase ID:  

HHID00063972

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-99a-3p:  MIMAT0004511          UBQLN2:  NM_013444     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-99a-3p	UBQLN2
miRBase Accession/Entrez ID	MIMAT0004511	29978
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	ALS15//CHAP1//DSK2//HRIHFB2157//N4BP4//PLIC2

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-99a-3p	rs1214222916 chr21:16539147    T/C rs1419616925 chr21:16539158    T/A rs763134262 chr21:16539151    A/G rs766428664 chr21:16539153    G/A rs774748688 chr21:16539159    G/C rs950382507 chr21:16539154    G/A rs1271070422 chr21:16539142    C/T rs913397001 chr21:16539145    G/A

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	UBQLN2	chrX:56590087-56590088(+) m6A 5'UTR       24284625//25456834//24981863//22575960//22608085 chrX:56590101-56590102(+) m6A 5'UTR       24284625//25456834//24981863//22575960//22608085 chrX:56590144-56590145(+) m6A 5'UTR       24284625//25456834//24981863//22575960//22608085 chrX:56590152-56590153(+) m6A 5'UTR       24284625//25456834//24981863//22575960//22608085 chrX:56590420-56590421(+) m6A CDS       24284625//24981863//22608085 chrX:56590457-56590458(+) m6A CDS       24284625//24981863//22608085 chrX:56590510-56590511(+) m6A CDS       24284625//24981863//26404942//22608085 chrX:56590622-56590623(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chrX:56590666-56590667(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chrX:56590755-56590756(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chrX:56590958-56590959(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chrX:56590991-56590992(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chrX:56591005-56591006(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chrX:56591060-56591061(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chrX:56591360-56591361(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085 chrX:56591441-56591442(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085 chrX:56591627-56591628(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chrX:56591648-56591649(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chrX:56591695-56591696(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chrX:56591764-56591765(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chrX:56591856-56591857(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chrX:56591941-56591942(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085 chrX:56591967-56591968(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chrX:56592066-56592067(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22608085 chrX:56592092-56592093(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22608085 chrX:56592104-56592105(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chrX:56592244-56592245(+) m6A 3'UTR       24284625//24209618//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-99a-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Skeletal muscle myoblasts     21637849
	UBQLN2	Exosome Blood     - Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-99a-3p
Interactor2: UBQLN2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.