Basic Information:

  VIRBase ID:  

HHID00063971

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-99a-3p:  MIMAT0004511          FNDC3A:  NR_103528     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-99a-3p	FNDC3A
miRBase Accession/Entrez ID	MIMAT0004511	22862
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	bA203I16.1//bA203I16.5//FNDC3//HUGO

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-99a-3p	rs1214222916 chr21:16539147    T/C rs1419616925 chr21:16539158    T/A rs763134262 chr21:16539151    A/G rs766428664 chr21:16539153    G/A rs774748688 chr21:16539159    G/C rs950382507 chr21:16539154    G/A rs1271070422 chr21:16539142    C/T rs913397001 chr21:16539145    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FNDC3A	chr13:49767552(+) A-I      intronic chr13:49651335(+) A-I      intronic chr13:49615849(+) A-I      intronic chr13:49766676(+) A-I      intronic chr13:49587275(+) A-I      intronic chr13:49615892(+) A-I      intronic chr13:49651366(+) A-I      intronic chr13:49767557(+) A-I      intronic chr13:49651364(+) A-I      intronic chr13:49651358(+) A-I      intronic chr13:49651336(+) A-I      intronic chr13:49563967(+) A-I      intronic chr13:49603222(+) A-I      intronic chr13:49615836(+) A-I      intronic chr13:49634546(+) A-I      intronic chr13:49654006(+) A-I      intronic chr13:49587294(+) A-I      intronic chr13:49764296(+) A-I      intronic chr13:49585877(+) A-I      intronic chr13:49767436(+) A-I      intronic chr13:49585826(+) A-I      intronic chr13:49619316(+) A-I      intronic chr13:49657779(+) A-I      intronic chr13:49619363(+) A-I      intronic chr13:49602611(+) A-I      intronic chr13:49565567(+) A-I      intronic chr13:49565658(+) A-I      intronic chr13:49616657(+) A-I      intronic chr13:49768310(+) A-I      intronic chr13:49767501(+) A-I      intronic chr13:49773590(+) A-I      intronic chr13:49585449(+) A-I      intronic chr13:49562715(+) A-I      intronic chr13:49618630(+) A-I      intronic chr13:49767477(+) A-I      intronic chr13:49586431(+) A-I      intronic chr13:49768235(+) A-I      intronic chr13:49634620(+) A-I      intronic chr13:49617156(+) A-I      intronic chr13:49755192(+) A-I      intronic chr13:49717418(+) A-I      intronic chr13:49633692(+) A-I      intronic chr13:49773563(+) A-I      intronic chr13:49772858(+) A-I      intronic chr13:49616706(+) A-I      intronic chr13:49772853(+) A-I      intronic chr13:49772839(+) A-I      intronic chr13:49654084(+) A-I      intronic chr13:49768324(+) A-I      intronic chr13:49768307(+) A-I      intronic chr13:49768148(+) A-I      intronic chr13:49767966(+) A-I      intronic chr13:49767536(+) A-I      intronic chr13:49767497(+) A-I      intronic chr13:49767452(+) A-I      intronic chr13:49766723(+) A-I      intronic chr13:49773564(+) A-I      intronic chr13:49766713(+) A-I      intronic chr13:49766680(+) A-I      intronic chr13:49756235(+) A-I      intronic chr13:49680579(+) A-I      intronic chr13:49662901(+) A-I      intronic chr13:49756218(+) A-I      intronic chr13:49756217(+) A-I      intronic chr13:49756204(+) A-I      intronic chr13:49756203(+) A-I      intronic chr13:49756182(+) A-I      intronic chr13:49755169(+) A-I      intronic chr13:49755097(+) A-I      intronic chr13:49754972(+) A-I      intronic chr13:49754888(+) A-I      intronic chr13:49724295(+) A-I      intronic chr13:49724285(+) A-I      intronic chr13:49724258(+) A-I      intronic chr13:49717398(+) A-I      intronic chr13:49717019(+) A-I      intronic chr13:49680699(+) A-I      intronic chr13:49680578(+) A-I      intronic chr13:49680542(+) A-I      intronic chr13:49678407(+) A-I      intronic chr13:49665036(+) A-I      intronic chr13:49654080(+) A-I      intronic chr13:49654077(+) A-I      intronic chr13:49634765(+) A-I      intronic chr13:49634705(+) A-I      intronic chr13:49634629(+) A-I      intronic chr13:49634566(+) A-I      intronic chr13:49634547(+) A-I      intronic chr13:49633854(+) A-I      intronic chr13:49633777(+) A-I      intronic chr13:49633728(+) A-I      intronic chr13:49633717(+) A-I      intronic chr13:49633691(+) A-I      intronic chr13:49633677(+) A-I      intronic chr13:49633672(+) A-I      intronic chr13:49619551(+) A-I      intronic chr13:49619510(+) A-I      intronic chr13:49619499(+) A-I      intronic chr13:49773175(+) A-I      intronic chr13:49619370(+) A-I      intronic chr13:49619354(+) A-I      intronic chr13:49618721(+) A-I      intronic chr13:49618709(+) A-I      intronic chr13:49618659(+) A-I      intronic chr13:49618559(+) A-I      intronic chr13:49618553(+) A-I      intronic chr13:49754904(+) A-I      intronic chr13:49617311(+) A-I      intronic chr13:49617299(+) A-I      intronic chr13:49585786(+) A-I      intronic chr13:49617291(+) A-I      intronic chr13:49617155(+) A-I      intronic chr13:49617131(+) A-I      intronic chr13:49606761(+) A-I      intronic chr13:49606757(+) A-I      intronic chr13:49603235(+) A-I      intronic chr13:49603228(+) A-I      intronic chr13:49602610(+) A-I      intronic chr13:49619432(+) A-I      intronic chr13:49602598(+) A-I      intronic chr13:49602597(+) A-I      intronic chr13:49602596(+) A-I      intronic chr13:49768232(+) A-I      intronic chr13:49602585(+) A-I      intronic chr13:49602550(+) A-I      intronic chr13:49602503(+) A-I      intronic chr13:49602477(+) A-I      intronic chr13:49602476(+) A-I      intronic chr13:49602438(+) A-I      intronic chr13:49602333(+) A-I      intronic chr13:49602202(+) A-I      intronic chr13:49602125(+) A-I      intronic chr13:49602109(+) A-I      intronic chr13:49587227(+) A-I      intronic chr13:49586448(+) A-I      intronic chr13:49586379(+) A-I      intronic chr13:49586367(+) A-I      intronic chr13:49585858(+) A-I      intronic chr13:49585853(+) A-I      intronic chr13:49585774(+) A-I      intronic chr13:49585585(+) A-I      intronic chr13:49585570(+) A-I      intronic chr13:49585550(+) A-I      intronic chr13:49585536(+) A-I      intronic chr13:49585535(+) A-I      intronic chr13:49585511(+) A-I      intronic chr13:49564818(+) A-I      intronic chr13:49585495(+) A-I      intronic chr13:49585474(+) A-I      intronic chr13:49565833(+) A-I      intronic chr13:49565745(+) A-I      intronic chr13:49565733(+) A-I      intronic chr13:49565716(+) A-I      intronic chr13:49564689(+) A-I      intronic chr13:49564088(+) A-I      intronic chr13:49564085(+) A-I      intronic chr13:49564068(+) A-I      intronic chr13:49564017(+) A-I      intronic chr13:49563992(+) A-I      intronic chr13:49563968(+) A-I      intronic chr13:49559092(+) A-I      intronic chr13:49767919(+) A-I      intronic chr13:49619394(+) A-I      intronic chr13:49600739(+) A-I      intronic chr13:49633781(+) A-I      intronic chr13:49724987(+) A-I      intronic chr13:49602184(+) A-I      intronic chr13:49606687(+) A-I      intronic chr13:49766451(+) A-I      intronic chr13:49603243(+) A-I      intronic chr13:49564777(+) A-I      intronic chr13:49619390(+) A-I      intronic chr13:49651152(+) A-I      intronic chr13:49634687(+) A-I      intronic chr13:49633867(+) A-I      intronic chr13:49634541(+) A-I      intronic chr13:49587304(+) A-I      intronic chr13:49654009(+) A-I      intronic chr13:49752933(+) A-I      intronic chr13:49767476(+) A-I      intronic chr13:49602078(+) A-I      intronic chr13:49755123(+) A-I      intronic chr13:49768135(+) A-I      intronic chr13:49754910(+) A-I      intronic chr13:49628200(+) A-I      intronic chr13:49634604(+) A-I      intronic chr13:49602542(+) A-I      intronic chr13:49633845(+) A-I      intronic chr13:49567442(+) A-I      intronic chr13:49754911(+) A-I      intronic chr13:49565695(+) A-I      intronic chr13:49602560(+) A-I      intronic chr13:49773568(+) A-I      intronic chr13:49618712(+) A-I      intronic chr13:49755103(+) A-I      intronic chr13:49634633(+) A-I      intronic chr13:49662969(+) A-I      intronic chr13:49756212(+) A-I      intronic chr13:49756185(+) A-I      intronic chr13:49602093(+) A-I      intronic chr13:49616656(+) A-I      intronic chr13:49619407(+) A-I      intronic chr13:49651273(+) A-I      intronic chr13:49585767(+) A-I      intronic chr13:49645532(+) A-I      intronic chr13:49564826(+) A-I      intronic chr13:49562799(+) A-I      intronic chr13:49767995(+) A-I      intronic chr13:49630090(+) A-I      intronic chr13:49756264(+) A-I      intronic chr13:49585781(+) A-I      intronic chr13:49615868(+) A-I      intronic chr13:49585444(+) A-I      intronic chr13:49585470(+) A-I      intronic chr13:49633797(+) A-I      intronic chr13:49749127(+) A-I      intronic chr13:49619321(+) A-I      intronic chr13:49619389(+) A-I      intronic chr13:49764522(+) A-I      intronic chr13:49618685(+) A-I      intronic chr13:49619419(+) A-I      intronic chr13:49565811(+) A-I      intronic chr13:49585782(+) A-I      intronic chr13:49642394(+) A-I      intronic chr13:49585872(+) A-I      intronic chr13:49627596(+) A-I      intronic chr13:49619487(+) A-I      intronic chr13:49585913(+) A-I      intronic chr13:49616769(+) A-I      intronic chr13:49756258(+) A-I      intronic chr13:49764046(+) A-I      intronic chr13:49562906(+) A-I      intronic chr13:49587301(+) A-I      intronic chr13:49585450(+) A-I      intronic chr13:49563981(+) A-I      intronic chr13:49662929(+) A-I      intronic chr13:49619470(+) A-I      intronic chr13:49615872(+) A-I      intronic chr13:49585799(+) A-I      intronic chr13:49642420(+) A-I      intronic chr13:49602471(+) A-I      intronic chr13:49653976(+) A-I      intronic chr13:49664905(+) A-I      intronic chr13:49619393(+) A-I      intronic chr13:49633772(+) A-I      intronic chr13:49773296(+) A-I      intronic chr13:49616721(+) A-I      intronic chr13:49773565(+) A-I      intronic chr13:49662890(+) A-I      intronic chr13:49629382(+) A-I      intronic chr13:49773368(+) A-I      intronic chr13:49563936(+) A-I      intronic chr13:49618699(+) A-I      intronic chr13:49603134(+) A-I      intronic chr13:49585920(+) A-I      intronic chr13:49642377(+) A-I      intronic chr13:49618628(+) A-I      intronic chr13:49630136(+) A-I      intronic chr13:49618750(+) A-I      intronic chr13:49768278(+) A-I      intronic chr13:49564819(+) A-I      intronic chr13:49602502(+) A-I      intronic chr13:49585852(+) A-I      intronic chr13:49633775(+) A-I      intronic chr13:49766543(+) A-I      intronic chr13:49633828(+) A-I      intronic chr13:49619490(+) A-I      intronic chr13:49755166(+) A-I      intronic chr13:49756187(+) A-I      intronic chr13:49662935(+) A-I      intronic chr13:49767971(+) A-I      intronic chr13:49642773(+) A-I      intronic chr13:49617192(+) A-I      intronic chr13:49630158(+) A-I      intronic chr13:49773181(+) A-I      intronic chr13:49629343(+) A-I      intronic chr13:49565568(+) A-I      intronic chr13:49680588(+) A-I      intronic chr13:49615896(+) A-I      intronic chr13:49767618(+) A-I      intronic chr13:49680665(+) A-I      intronic chr13:49602165(+) A-I      intronic chr13:49645384(+) A-I      intronic chr13:49629340(+) A-I      intronic chr13:49619360(+) A-I      intronic chr13:49767836(+) A-I      intronic chr13:49617362(+) A-I      intronic chr13:49767632(+) A-I      intronic chr13:49772790(+) A-I      intronic chr13:49767529(+) A-I      intronic chr13:49600658(+) A-I      intronic chr13:49618627(+) A-I      intronic chr13:49724322(+) A-I      intronic chr13:49617191(+) A-I      intronic chr13:49616854(+) A-I      intronic chr13:49602494(+) A-I      intronic chr13:49619525(+) A-I      intronic chr13:49630186(+) A-I      intronic chr13:49562731(+) A-I      intronic chr13:49755080(+) A-I      intronic chr13:49562722(+) A-I      intronic chr13:49564655(+) A-I      intronic chr13:49634618(+) A-I      intronic chr13:49767841(+) A-I      intronic chr13:49619473(+) A-I      intronic chr13:49617375(+) A-I      intronic chr13:49644964(+) A-I      intronic chr13:49616695(+) A-I      intronic chr13:49564027(+) A-I      intronic chr13:49564610(+) A-I      intronic chr13:49642361(+) A-I      intronic chr13:49585888(+) A-I      intronic chr13:49642357(+) A-I      intronic chr13:49717213(+) A-I      intronic chr13:49615782(+) A-I      intronic chr13:49618629(+) A-I      intronic chr13:49767471(+) A-I      intronic chr13:49768006(+) A-I      intronic chr13:49725068(+) A-I      intronic chr13:49585848(+) A-I      intronic chr13:49634624(+) A-I      intronic chr13:49619329(+) A-I      intronic chr13:49651204(+) A-I      intronic chr13:49772812(+) A-I      intronic chr13:49630103(+) A-I      intronic chr13:49585469(+) A-I      intronic chr13:49562899(+) A-I      intronic chr13:49564029(+) A-I      intronic chr13:49587395(+) A-I      intronic chr13:49763400(+) A-I      intronic chr13:49619541(+) A-I      intronic chr13:49767546(+) A-I      intronic chr13:49617193(+) A-I      intronic chr13:49768019(+) A-I      intronic chr13:49634683(+) A-I      intronic chr13:49630243(+) A-I      intronic chr13:49662884(+) A-I      intronic chr13:49767650(+) A-I      intronic chr13:49602244(+) A-I      intronic chr13:49563987(+) A-I      intronic chr13:49564823(+) A-I      intronic chr13:49562796(+) A-I      intronic chr13:49587298(+) A-I      intronic chr13:49654168(+) A-I      intronic chr13:49767490(+) A-I      intronic chr13:49585812(+) A-I      intronic chr13:49602543(+) A-I      intronic chr13:49616650(+) A-I      intronic chr13:49585463(+) A-I      intronic chr13:49662936(+) A-I      intronic chr13:49767936(+) A-I      intronic chr13:49564799(+) A-I      intronic chr13:49602644(+) A-I      intronic chr13:49587299(+) A-I      intronic chr13:49768128(+) A-I      intronic chr13:49602563(+) A-I      intronic chr13:49562876(+) A-I      intronic chr13:49615889(+) A-I      intronic chr13:49615848(+) A-I      intronic chr13:49642679(+) A-I      intronic chr13:49617143(+) A-I      intronic chr13:49585409(+) A-I      intronic chr13:49772813(+) A-I      intronic chr13:49619455(+) A-I      intronic chr13:49602489(+) A-I      intronic chr13:49767570(+) A-I      intronic chr13:49766452(+) A-I      intronic chr13:49563988(+) A-I      intronic chr13:49602188(+) A-I      intronic chr13:49772806(+) A-I      intronic chr13:49615902(+) A-I      intronic chr13:49602432(+) A-I      intronic chr13:49565668(+) A-I      intronic chr13:49585921(+) A-I      intronic chr13:49725086(+) A-I      intronic chr13:49772890(+) A-I      intronic chr13:49767633(+) A-I      intronic chr13:49630068(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FNDC3A	chr13:49564777(+) A-I intron -    22327324 chr13:49602078(+) A-I intron -    22327324 chr13:49616695(+) A-I intron -    22327324 chr13:49662890(+) A-I intron -    22327324 chr13:49772813(+) A-I intron -    22327324 chr13:49773175(+) A-I intron -    22327324 chr13:49773176(+) A-I intron -    22327324 chr13:49567442(+) A-G intron -    22484847 chr13:49619220(+) T-C intron -    22484847 chr13:49627596(+) A-G intron -    22484847 chr13:49628200(+) A-G intron -    22484847 chr13:49642679(+) A-G intron -    22484847 chr13:49644964(+) A-G intron -    22484847 chr13:49645532(+) A-G intron -    22484847 chr13:49562715(+) A-G intron -    22484847 chr13:49563981(+) A-G intron -    22484847 chr13:49564777(+) A-G intron -    22484847 chr13:49564818(+) A-G intron -    22484847 chr13:49564819(+) A-G intron -    22484847 chr13:49564823(+) A-G intron -    22484847 chr13:49565567(+) A-G intron -    22484847 chr13:49602078(+) A-G intron -    22484847 chr13:49602432(+) A-G intron -    22484847 chr13:49602489(+) A-G intron -    22484847 chr13:49602502(+) A-G intron -    22484847 chr13:49602543(+) A-G intron -    22484847 chr13:49615902(+) A-G intron -    22484847 chr13:49616650(+) A-G intron -    22484847 chr13:49616695(+) A-G intron -    22484847 chr13:49616706(+) A-G intron -    22484847 chr13:49616721(+) A-G intron -    22484847 chr13:49617193(+) A-G intron -    22484847 chr13:49617375(+) A-G intron -    22484847 chr13:49618627(+) A-G intron -    22484847 chr13:49633828(+) A-G intron -    22484847 chr13:49642420(+) A-G intron -    22484847 chr13:49662890(+) A-G intron -    22484847 chr13:49767471(+) A-G intron -    22484847 chr13:49772790(+) A-G intron -    22484847 chr13:49772806(+) A-G intron -    22484847 chr13:49772812(+) A-G intron -    22484847 chr13:49772813(+) A-G intron -    22484847 chr13:49773175(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FNDC3A	chr13:49550102-49550103(+) m6A 5'UTR       24284625//24209618//24981863 chr13:49550171-49550172(+) m6A 5'UTR       24284625//24209618//24981863//27371828 chr13:49550242-49550243(+) m6A 5'UTR       24209618 chr13:49550255-49550256(+) m6A 5'UTR       24209618 chr13:49710520-49710521(+) m6A CDS       24981863//27773535 chr13:49710562-49710563(+) m6A CDS       24981863//27773535//22608085 chr13:49710627-49710628(+) m6A CDS       24981863//27773535//22608085 chr13:49710636-49710637(+) m6A CDS       24981863//27773535//22608085 chr13:49710648-49710649(+) m6A CDS       24981863//27773535//22608085 chr13:49710668-49710669(+) m6A CDS       24981863//27773535//22608085 chr13:49712896-49712897(+) m6A CDS       24981863//27773535 chr13:49742779-49742780(+) m6A CDS       27773535 chr13:49742820-49742821(+) m6A CDS       27773535 chr13:49742857-49742858(+) m6A CDS       27773535 chr13:49746209-49746210(+) m6A CDS       27773535 chr13:49772319-49772320(+) m6A 3'UTR//CDS       24284625 chr13:49772332-49772333(+) m6A 3'UTR//CDS       24284625 chr13:49777416-49777417(+) m6A 3'UTR//CDS       24284625//24209618//27773535 chr13:49781265-49781266(+) m6A 3'UTR//CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr13:49781310-49781311(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr13:49781320-49781321(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr13:49781328-49781329(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr13:49781375-49781376(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr13:49781380-49781381(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr13:49781403-49781404(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr13:49781423-49781424(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr13:49783507-49783508(+) m6A 3'UTR       27773535 chr13:49783558-49783559(+) m6A 3'UTR       27773535 chr13:49783565-49783566(+) m6A 3'UTR       27773535 chr13:49783595-49783596(+) m6A 3'UTR       27773535 chr13:49783629-49783630(+) m6A 3'UTR       27773535 chr13:49783668-49783669(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-99a-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Skeletal muscle myoblasts     21637849
	FNDC3A	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-99a-3p
Interactor2: FNDC3A

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.