Detail Information

Basic Information:


  VIRBase ID:  

HHID00063880

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-92a-2-5p:           RNF141:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-92a-2-5p RNF141
miRBase
Accession/Entrez ID		 MIMAT0004508 50862
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - RFP141//ZFP26//ZNF230

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-92a-2-5p
rs1410543065 chrX:134169584    T/C
rs1472671311 chrX:134169587    T/C
rs377133365 chrX:134169588    G/A
rs377133365 chrX:134169588    G/C
rs745614747 chrX:134169602    C/T
rs769366736 chrX:134169603    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RNF141
chr11:10534238(-) A-I      3'UTR
chr11:10535402(-) A-I      3'UTR
chr11:10535496(-) A-I      3'UTR
chr11:10535502(-) A-I      3'UTR
chr11:10534242(-) A-I      3'UTR
chr11:10535362(-) A-I      3'UTR
chr11:10534231(-) A-I      3'UTR
chr11:10535380(-) A-I      3'UTR
chr11:10535372(-) A-I      3'UTR
chr11:10535356(-) A-I      3'UTR
chr11:10535339(-) A-I      3'UTR
chr11:10535391(-) A-I      3'UTR
chr11:10535495(-) A-I      3'UTR
chr11:10535392(-) A-I      3'UTR
chr11:10535455(-) A-I      3'UTR
chr11:10535418(-) A-I      3'UTR
chr11:10535405(-) A-I      3'UTR
chr11:10535393(-) A-I      3'UTR
chr11:10535394(-) A-I      3'UTR
chr11:10534263(-) A-I      3'UTR
chr11:10534281(-) A-I      3'UTR
chr11:10534282(-) A-I      3'UTR
chr11:10534290(-) A-I      3'UTR
chr11:10535397(-) A-I      3'UTR
chr11:10535388(-) A-I      3'UTR
chr11:10535259(-) A-I      3'UTR
chr11:10535361(-) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RNF141
chr11:10535102-10535103(-) m6A 3'UTR//exon       27773535
chr11:10535234-10535235(-) m6A 3'UTR//exon       24981863
chr11:10535253-10535254(-) m6A 3'UTR//exon       24981863
chr11:10535263-10535264(-) m6A 3'UTR//exon       24981863
chr11:10555699-10555700(-) m6A CDS       27371828
chr11:10555717-10555718(-) m6A 5'UTR       27371828
chr11:10555749-10555750(-) m6A 5'UTR       27371828
chr11:10562323-10562324(-) m6A 5'UTR//intron       24981863//27371828
chr11:10562401-10562402(-) m6A 5'UTR//intron       24981863//27371828
chr11:10562674-10562675(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-92a-2-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
Mitochondrion Cell line (HEK-293)     22984580
RNF141
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-92a-2-5p
Diethylstilbestrol 448537 Drug interaction    RC00006830
Carboplatinum 38904 Drug interaction    RC00006829
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00006828
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-92a-2-5p
Carboplatin 426756       20548249

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-92a-2-5p
Interactor2: RNF141

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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