Detail Information

Basic Information:


  VIRBase ID:  

HHID00063876

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-92a-2-5p:           MYLIP:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-92a-2-5p MYLIP
miRBase
Accession/Entrez ID		 MIMAT0004508 29116
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - IDOL//MIR

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-92a-2-5p
rs1410543065 chrX:134169584    T/C
rs1472671311 chrX:134169587    T/C
rs377133365 chrX:134169588    G/A
rs377133365 chrX:134169588    G/C
rs745614747 chrX:134169602    C/T
rs769366736 chrX:134169603    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MYLIP
chr6:16139521(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MYLIP
chr6:16129419-16129420(+) m6A 5'UTR       24284625//24981863
chr6:16129626-16129627(+) m6A 5'UTR//CDS       24284625//24209618
chr6:16130828-16130829(+) m6A CDS//intron       24284625
chr6:16145210-16145211(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr6:16145251-16145252(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:16145309-16145310(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr6:16145324-16145325(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr6:16145375-16145376(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr6:16145410-16145411(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr6:16147001-16147002(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr6:16147020-16147021(+) m6A 3'UTR       24284625//24209618//24981863//22608085
chr6:16147035-16147036(+) m6A 3'UTR       24284625//24209618//24981863//22608085
chr6:16147148-16147149(+) m6A 3'UTR       24284625//24981863//22608085
chr6:16147186-16147187(+) m6A 3'UTR       24284625//22608085
chr6:16147210-16147211(+) m6A 3'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-92a-2-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
Mitochondrion Cell line (HEK-293)     22984580
MYLIP
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -
Ribosome HEK-293 cells     22199352

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-92a-2-5p
Diethylstilbestrol 448537 Drug interaction    RC00006830
Carboplatinum 38904 Drug interaction    RC00006829
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00006828
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-92a-2-5p
Carboplatin 426756       20548249

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-92a-2-5p
Interactor2: MYLIP

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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