Detail Information

Basic Information:


  VIRBase ID:  

HHID00063820

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-92a-2-5p:           PSMD5:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-92a-2-5p PSMD5
miRBase
Accession/Entrez ID		 MIMAT0004508 5711
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - S5B

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-92a-2-5p
rs1410543065 chrX:134169584    T/C
rs1472671311 chrX:134169587    T/C
rs377133365 chrX:134169588    G/A
rs377133365 chrX:134169588    G/C
rs745614747 chrX:134169602    C/T
rs769366736 chrX:134169603    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PSMD5
chr9:123603054(-) A-I      intronic
chr9:123603036(-) A-I      intronic
chr9:123603019(-) A-I      intronic
chr9:123599733(-) A-I      intronic
chr9:123603097(-) A-I      intronic
chr9:123596121(-) A-I      intronic
chr9:123596432(-) A-I      intronic
chr9:123586386(-) A-I      intronic
chr9:123597866(-) A-I      intronic
chr9:123596113(-) A-I      intronic
chr9:123586333(-) A-I      intronic
chr9:123603735(-) A-I      intronic
chr9:123603676(-) A-I      intronic
chr9:123596463(-) A-I      intronic
chr9:123596437(-) A-I      intronic
chr9:123593200(-) A-I      intronic
chr9:123603673(-) A-I      intronic
chr9:123585936(-) A-I      intronic
chr9:123597820(-) A-I      intronic
chr9:123603614(-) A-I      intronic
chr9:123603613(-) A-I      intronic
chr9:123603124(-) A-I      intronic
chr9:123603110(-) A-I      intronic
chr9:123603080(-) A-I      intronic
chr9:123585901(-) A-I      intronic
chr9:123579761(-) A-I      3'UTR
chr9:123579766(-) A-I      3'UTR
chr9:123579764(-) A-I      3'UTR
chr9:123579634(-) A-I      3'UTR
chr9:123579654(-) A-I      3'UTR
chr9:123579677(-) A-I      3'UTR
chr9:123579730(-) A-I      3'UTR
chr9:123579789(-) A-I      3'UTR
chr9:123579790(-) A-I      3'UTR
chr9:123579828(-) A-I      3'UTR
chr9:123579724(-) A-I      3'UTR
chr9:123579741(-) A-I      3'UTR
chr9:123579742(-) A-I      3'UTR
chr9:123579752(-) A-I      3'UTR
chr9:123602284(-) A-I      intronic
chr9:123596537(-) A-I      intronic
chr9:123584874(-) A-I      intronic
chr9:123602348(-) A-I      intronic
chr9:123603303(-) A-I      intronic
chr9:123584826(-) A-I      intronic
chr9:123602236(-) A-I      intronic
chr9:123596085(-) A-I      intronic
chr9:123596459(-) A-I      intronic
chr9:123582002(-) A-I      intronic
chr9:123586387(-) A-I      intronic
chr9:123602137(-) A-I      intronic
chr9:123596094(-) A-I      intronic
chr9:123585149(-) A-I      intronic
chr9:123602875(-) A-I      intronic
chr9:123579767(-) A-I      3'UTR
chr9:123579743(-) A-I      3'UTR
chr9:123579673(-) A-I      3'UTR
chr9:123579824(-) A-I      3'UTR
chr9:123579744(-) A-I      3'UTR
chr9:123602540(-) A-I      intronic
chr9:123597746(-) A-I      intronic
chr9:123603168(-) A-I      intronic
chr9:123596130(-) A-I      intronic
chr9:123602294(-) A-I      intronic
chr9:123602330(-) A-I      intronic
chr9:123602677(-) A-I      intronic
chr9:123590885(-) A-I      intronic
chr9:123585910(-) A-I      intronic
chr9:123602664(-) A-I      intronic
chr9:123602862(-) A-I      intronic
chr9:123585602(-) A-I      intronic
chr9:123603668(-) A-I      intronic
chr9:123586042(-) A-I      intronic
chr9:123598025(-) A-I      intronic
chr9:123602495(-) A-I      intronic
chr9:123585117(-) A-I      intronic
chr9:123585844(-) A-I      intronic
chr9:123603235(-) A-I      intronic
chr9:123586332(-) A-I      intronic
chr9:123597887(-) A-I      intronic
chr9:123602319(-) A-I      intronic
chr9:123597925(-) A-I      intronic
chr9:123603225(-) A-I      intronic
chr9:123602282(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PSMD5
chr9:123585910(-) A-I intron -    22327324
chr9:123598407(-) A-I intron -    21960545
chr9:123604447(-) T-G intron -    22484847
chr9:123579638(-) A-G exon 3'UTR    22484847
chr9:123585910(-) A-G intron -    22484847
chr9:123596531(-) A-G intron -    22484847
chr9:123596537(-) A-G intron -    22484847
chr9:123602862(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PSMD5
chr9:123578518-123578519(-) m6A 3'UTR//intron       27773535
chr9:123578532-123578533(-) m6A 3'UTR//intron       27773535
chr9:123578902-123578903(-) m6A 3'UTR//intron       27773535
chr9:123578993-123578994(-) m6A 3'UTR//intron       27773535
chr9:123579098-123579099(-) m6A 3'UTR//intron       26404942//27773535
chr9:123579107-123579108(-) m6A 3'UTR//intron       26404942//27773535
chr9:123579118-123579119(-) m6A 3'UTR//intron       26404942//27773535
chr9:123579133-123579134(-) m6A 3'UTR//intron       26404942//27773535
chr9:123579542-123579543(-) m6A 3'UTR//intron       27773535
chr9:123579575-123579576(-) m6A 3'UTR//intron       24981863//27773535
chr9:123579740-123579741(-) m6A 3'UTR//intron       27773535
chr9:123579763-123579764(-) m6A 3'UTR//intron       24284625//24981863//27773535
chr9:123579878-123579879(-) m6A 3'UTR//intron       24284625//24209618//24981863//26404942//27773535
chr9:123579980-123579981(-) m6A 3'UTR//intron       24284625//24209618//24981863//26404942//27773535
chr9:123580009-123580010(-) m6A 3'UTR//intron       24284625//24209618//24981863//26404942//27773535
chr9:123580097-123580098(-) m6A 3'UTR//intron       24284625//24209618//24981863//26404942//27773535//22575960
chr9:123580141-123580142(-) m6A 3'UTR//intron       24284625//24209618//24981863//26404942//27773535//22575960
chr9:123580158-123580159(-) m6A 3'UTR//intron       24284625//24209618//24981863//26404942//27773535//22575960
chr9:123580219-123580220(-) m6A CDS//intron       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960
chr9:123580251-123580252(-) m6A CDS//intron       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960
chr9:123580274-123580275(-) m6A CDS//intron       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960
chr9:123580296-123580297(-) m6A CDS//intron       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960
chr9:123580324-123580325(-) m6A CDS//intron       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960
chr9:123580370-123580371(-) m6A CDS//intron       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960
chr9:123580411-123580412(-) m6A CDS//intron       24284625//24209618//24981863//27773535//27371828//22575960
chr9:123580430-123580431(-) m6A CDS//intron       24284625//24209618//24981863//27773535//27371828//22575960
chr9:123583146-123583147(-) m6A CDS       24284625
chr9:123583244-123583245(-) m6A CDS       24284625
chr9:123593640-123593641(-) m6A CDS//exon//intron       22575960

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-92a-2-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
Mitochondrion Cell line (HEK-293)     22984580
PSMD5
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-92a-2-5p
Diethylstilbestrol 448537 Drug interaction    RC00006830
Carboplatinum 38904 Drug interaction    RC00006829
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00006828
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-92a-2-5p
Carboplatin 426756       20548249

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-92a-2-5p
Interactor2: PSMD5

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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