Detail Information

Basic Information:


  VIRBase ID:  

HHID00063381

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-19b-2-5p:           POLI:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-19b-2-5p POLI
miRBase
Accession/Entrez ID		 MIMAT0004492 11201
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - eta2//RAD30B//RAD3OB

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-19b-2-5p
rs193073651 chrX:134169728    G/A
rs749008511 chrX:134169737    A/C
rs755951722 chrX:134169731    A/G
rs779795647 chrX:134169732    T/C
rs747654746 chrX:134169746    A/G
rs754566533 chrX:134169743    A/G
rs778397250 chrX:134169744    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR POLI
chr18:51812353(+) A-I      intronic
chr18:51813220(+) A-I      intronic
chr18:51813118(+) A-I      intronic
chr18:51813094(+) A-I      intronic
chr18:51812299(+) A-I      intronic
chr18:51812398(+) A-I      intronic
chr18:51813064(+) A-I      intronic
chr18:51822137(+) A-I      3'UTR
chr18:51813104(+) A-I      intronic
chr18:51801556(+) A-I      intronic
chr18:51812468(+) A-I      intronic
chr18:51812469(+) A-I      intronic
chr18:51813155(+) A-I      intronic
chr18:51804576(+) A-I      intronic
chr18:51804607(+) A-I      intronic
chr18:51812264(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED POLI
chr18:51796757(+) T-C intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase POLI
chr18:51795869-51795870(+) m6A 5'UTR       25456834
chr18:51795996-51795997(+) m6A 5'UTR//CDS//exon       24209618//25456834//24981863
chr18:51820028-51820029(+) m6A 3'UTR//CDS//exon//intron       24981863//22608085
chr18:51820055-51820056(+) m6A 3'UTR//CDS//exon//intron       24981863//22608085
chr18:51820063-51820064(+) m6A 3'UTR//CDS//exon//intron       24981863//22608085
chr18:51820108-51820109(+) m6A 3'UTR//CDS//exon//intron       24284625//24981863//22608085
chr18:51820154-51820155(+) m6A 3'UTR//CDS//exon//intron       24284625//24981863//22608085
chr18:51820389-51820390(+) m6A 3'UTR//CDS//intron       22608085
chr18:51820416-51820417(+) m6A 3'UTR//CDS//intron       22608085
chr18:51820423-51820424(+) m6A 3'UTR//CDS//intron       22608085
chr18:51820524-51820525(+) m6A 3'UTR//CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085
chr18:51820533-51820534(+) m6A 3'UTR//CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085
chr18:51820562-51820563(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr18:51820595-51820596(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr18:51820625-51820626(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr18:51820651-51820652(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr18:51820664-51820665(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr18:51820677-51820678(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr18:51820758-51820759(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr18:51820782-51820783(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr18:51820827-51820828(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//22608085
chr18:51820918-51820919(+) m6A 3'UTR//intron       24209618//24981863//27773535//22608085
chr18:51820947-51820948(+) m6A 3'UTR//intron       24981863//27773535//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-19b-2-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
POLI
Chromatin K562 cells     -
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-19b-2-5p
Interactor2: POLI

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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