Detail Information

Basic Information:


  VIRBase ID:  

HHID00063239

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-19b-1-5p:           MMGT1:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-19b-1-5p MMGT1
miRBase
Accession/Entrez ID		 MIMAT0004491 93380
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - EMC5//TMEM32

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-19b-1-5p
rs1330845252 chr13:91351221    G/A
rs771220050 chr13:91351229    C/T
rs1259633726 chr13:91351212    T/G
rs1279688822 chr13:91351213    G/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MMGT1
chrX:135052992(-) A-I      intronic
chrX:135048677(-) A-I      intronic
chrX:135053064(-) A-I      intronic
chrX:135053054(-) A-I      intronic
chrX:135053016(-) A-I      intronic
chrX:135052436(-) A-I      intronic
chrX:135051665(-) A-I      intronic
chrX:135050818(-) A-I      intronic
chrX:135052388(-) A-I      intronic
chrX:135051677(-) A-I      intronic
chrX:135052352(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MMGT1
chrX:135044511-135044512(-) m6A 3'UTR       -
chrX:135045337-135045338(-) m6A 3'UTR       24981863//27773535
chrX:135045360-135045361(-) m6A 3'UTR       24981863//27773535
chrX:135045539-135045540(-) Tm 3'UTR       -
chrX:135047073-135047074(-) m6A 3'UTR       24284625//24981863//26404942
chrX:135047116-135047117(-) m6A 3'UTR       24284625//24981863//26404942
chrX:135047151-135047152(-) m6A 3'UTR       24284625//24981863//26404942
chrX:135047156-135047157(-) m6A 3'UTR       24284625//24981863//26404942
chrX:135047203-135047204(-) m6A CDS       24284625//24981863
chrX:135047246-135047247(-) m6A CDS       24284625
chrX:135049559-135049560(-) m6A CDS       24284625
chrX:135049578-135049579(-) m6A CDS       24284625

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-19b-1-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Mesenchymal stem cells     -
MMGT1
Exosome Blood     -
Nucleolus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-19b-1-5p
Interactor2: MMGT1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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