Detail Information

Basic Information:


  VIRBase ID:  

HHID00063107

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-19b-1-5p:           ACOX3:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-19b-1-5p ACOX3
miRBase
Accession/Entrez ID		 MIMAT0004491 8310
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-19b-1-5p
rs1330845252 chr13:91351221    G/A
rs771220050 chr13:91351229    C/T
rs1259633726 chr13:91351212    T/G
rs1279688822 chr13:91351213    G/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ACOX3
chr4:8432439(-) A-I      intronic
chr4:8434089(-) A-I      intronic
chr4:8400381(-) A-I      intronic
chr4:8400385(-) A-I      intronic
chr4:8400406(-) A-I      intronic
chr4:8432435(-) A-I      intronic
chr4:8432420(-) A-I      intronic
chr4:8373922(-) A-I      intronic
chr4:8400476(-) A-I      intronic
chr4:8374030(-) A-I      intronic
chr4:8399671(-) A-I      intronic
chr4:8432570(-) A-I      intronic
chr4:8400380(-) A-I      intronic
chr4:8437101(-) A-I      intronic
chr4:8399708(-) A-I      intronic
chr4:8434099(-) A-I      intronic
chr4:8369651(-) A-I      intronic
chr4:8400277(-) A-I      intronic
chr4:8399739(-) A-I      intronic
chr4:8399683(-) A-I      intronic
chr4:8432501(-) A-I      intronic
chr4:8400492(-) A-I      intronic
chr4:8399830(-) A-I      intronic
chr4:8432332(-) A-I      intronic
chr4:8438597(-) A-I      intronic
chr4:8373879(-) A-I      intronic
chr4:8400307(-) A-I      intronic
chr4:8399776(-) A-I      intronic
chr4:8400399(-) A-I      intronic
chr4:8370674(-) A-I      intronic
chr4:8399725(-) A-I      intronic
chr4:8400453(-) A-I      intronic
chr4:8382055(-) A-I      intronic
chr4:8369672(-) A-I      intronic
chr4:8400470(-) A-I      intronic
chr4:8399629(-) A-I      intronic
chr4:8400367(-) A-I      intronic
chr4:8370615(-) A-I      intronic
chr4:8369636(-) A-I      intronic
chr4:8399740(-) A-I      intronic
chr4:8399891(-) A-I      intronic
chr4:8432514(-) A-I      intronic
chr4:8434227(-) A-I      intronic
chr4:8399722(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ACOX3
chr4:8369636(-) A-G intron -    22484847
chr4:8369672(-) A-G intron -    22484847
chr4:8370554(-) A-G intron -    22484847
chr4:8399830(-) A-G intron -    22484847
chr4:8399891(-) A-G intron -    22484847
chr4:8400399(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ACOX3
chr4:8368128-8368129(-) m6A 3'UTR       24981863//27773535
chr4:8368157-8368158(-) m6A 3'UTR       24981863//27773535
chr4:8368169-8368170(-) m6A 3'UTR       24981863//27773535
chr4:8368501-8368502(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr4:8368558-8368559(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr4:8368607-8368608(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr4:8368628-8368629(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr4:8368643-8368644(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr4:8368682-8368683(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr4:8368720-8368721(-) m6A 3'UTR//CDS//exon       24284625//24981863//28052920//27773535
chr4:8368724-8368725(-) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr4:8368796-8368797(-) m6A 3'UTR//CDS//exon       24284625//25456834//24981863//27371828//27773536//22608085
chr4:8372662-8372663(-) m6A 3'UTR//CDS//exon       24284625//27371828//27773536
chr4:8396349-8396350(-) m6A CDS//exon       24284625
chr4:8396362-8396363(-) m6A CDS//exon       24284625
chr4:8396376-8396377(-) m6A CDS//exon       24284625
chr4:8430156-8430157(-) m6A 5'UTR//intron       24284625//24981863
chr4:8442389-8442390(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-19b-1-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Mesenchymal stem cells     -
ACOX3
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-19b-1-5p
Interactor2: ACOX3

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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