Basic Information:

  VIRBase ID:  

HHID00063047

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-19b-1-5p:  MIMAT0004491          CCNG2:  NM_004354     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-19b-1-5p	CCNG2
miRBase Accession/Entrez ID	MIMAT0004491	901
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-19b-1-5p	rs1330845252 chr13:91351221    G/A rs771220050 chr13:91351229    C/T rs1259633726 chr13:91351212    T/G rs1279688822 chr13:91351213    G/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CCNG2	chr4:78092470(+) A-I      intronic chr4:78092456(+) A-I      intronic chr4:78092452(+) A-I      intronic chr4:78092494(+) A-I      intronic chr4:78086674(+) A-I      intronic chr4:78094529(+) A-I      intronic chr4:78092579(+) A-I      intronic chr4:78094696(+) A-I      intronic chr4:78092672(+) A-I      intronic chr4:78092514(+) A-I      intronic chr4:78111062(+) A-I      intronic chr4:78094537(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CCNG2	chr4:78078359-78078360(+) m6A 5'UTR       24981863 chr4:78078372-78078373(+) m6A 5'UTR       24981863 chr4:78078539-78078540(+) m6A 5'UTR//exon       24209618 chr4:78078580-78078581(+) m6A 5'UTR//exon       24209618 chr4:78078618-78078619(+) m6A 5'UTR//exon       24209618 chr4:78079474-78079475(+) m6A 5'UTR//intron       24209618

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-19b-1-5p	Exosome Jurkat-derived T cell line (J77cl20)     21505438 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Mesenchymal stem cells     -
	CCNG2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleus HCC cell line (HepG2)     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-19b-1-5p
Interactor2: CCNG2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.