Detail Information

Basic Information:


  VIRBase ID:  

HHID00063030

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-19a-5p:           KLHL15:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-19a-5p KLHL15
miRBase
Accession/Entrez ID		 MIMAT0004490 80311
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HEL-S-305

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-19a-5p
rs1162564162 chr13:91350912    A/G
rs1170543143 chr13:91350916    T/C
rs1388542964 chr13:91350918    G/C
rs1403138754 chr13:91350923    A/C
rs1442807536 chr13:91350921    C/G
rs764765453 chr13:91350924    CAAG/C
rs1051963210 chr13:91350909    T/C
rs756288295 chr13:91350905    G/A
rs780315531 chr13:91350911    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR KLHL15
chrX:24021000(-) A-I      intronic
chrX:24021009(-) A-I      intronic
chrX:24022411(-) A-I      intronic
chrX:24037037(-) A-I      intronic
chrX:24041116(-) A-I      intronic
chrX:24007564(-) A-I      intronic
chrX:24036915(-) A-I      intronic
chrX:24022373(-) A-I      intronic
chrX:24031415(-) A-I      intronic
chrX:24007565(-) A-I      intronic
chrX:24014608(-) A-I      intronic
chrX:24022416(-) A-I      intronic
chrX:24014632(-) A-I      intronic
chrX:24037120(-) A-I      intronic
chrX:24014636(-) A-I      intronic
chrX:24016575(-) A-I      intronic
chrX:24026612(-) A-I      intronic
chrX:24037034(-) A-I      intronic
chrX:24036049(-) A-I      intronic
chrX:24040910(-) A-I      intronic
chrX:24018442(-) A-I      intronic
chrX:24034451(-) A-I      intronic
chrX:24014685(-) A-I      intronic
chrX:24036222(-) A-I      intronic
chrX:24017315(-) A-I      intronic
chrX:24029639(-) A-I      intronic
chrX:24026564(-) A-I      intronic
chrX:24040264(-) A-I      intronic
chrX:24037576(-) A-I      intronic
chrX:24040639(-) A-I      intronic
chrX:24021020(-) A-I      intronic
chrX:24029637(-) A-I      intronic
chrX:24020953(-) A-I      intronic
chrX:24008173(-) A-I      intronic
chrX:24041016(-) A-I      intronic
chrX:24040295(-) A-I      intronic
chrX:24041044(-) A-I      intronic
chrX:24018441(-) A-I      intronic
chrX:24036868(-) A-I      intronic
chrX:24014583(-) A-I      intronic
chrX:24008185(-) A-I      intronic
chrX:24031653(-) A-I      intronic
chrX:24016350(-) A-I      intronic
chrX:24020995(-) A-I      intronic
chrX:24036889(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase KLHL15
chrX:24005510-24005511(-) m6A 3'UTR       27773535
chrX:24005957-24005958(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chrX:24005971-24005972(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chrX:24006006-24006007(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chrX:24006071-24006072(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chrX:24006149-24006150(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:24006230-24006231(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:24006285-24006286(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:24006297-24006298(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:24006471-24006472(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chrX:24006480-24006481(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chrX:24006487-24006488(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chrX:24006495-24006496(-) m6A CDS       24284625//24981863//27773535//27371828//22575960//22608085
chrX:24006588-24006589(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chrX:24006598-24006599(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chrX:24006678-24006679(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chrX:24006690-24006691(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chrX:24006782-24006783(-) m6A CDS       24284625//24981863//27773535//27371828//22575960//22608085
chrX:24006787-24006788(-) m6A CDS       24284625//24981863//27773535//27371828//22575960//22608085
chrX:24006943-24006944(-) m6A CDS       24284625//24981863//22575960//22608085
chrX:24006982-24006983(-) m6A CDS       24284625//24981863//26404942//22575960//22608085
chrX:24007008-24007009(-) m6A CDS       24284625//24981863//26404942//22608085
chrX:24007015-24007016(-) m6A CDS       24284625//24981863//26404942//22608085
chrX:24024171-24024172(-) m6A CDS       22608085
chrX:24024331-24024332(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chrX:24024346-24024347(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chrX:24024373-24024374(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chrX:24024396-24024397(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chrX:24024533-24024534(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chrX:24024601-24024602(-) m6A CDS       24284625//24981863//26404942//27773535//22575960//22608085
chrX:24024622-24024623(-) m6A CDS       24284625//24981863//27773535//22608085
chrX:24042982-24042983(-) m6A 5'UTR       27773536
chrX:24042987-24042988(-) m6A 5'UTR       27773536
chrX:24043009-24043010(-) m6A 5'UTR       27773536
chrX:24045259-24045260(-) m6A 5'UTR       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-19a-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
KLHL15
Cytosol HeLa-S3 cells     -
Exosome Blood     -
Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-19a-5p
Interactor2: KLHL15

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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