Basic Information:

  VIRBase ID:  

HHID00062989

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-19a-5p:  MIMAT0004490          MAX:  NR_073137     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-19a-5p	MAX
miRBase Accession/Entrez ID	MIMAT0004490	4149
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	bHLHd4

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-19a-5p	rs1162564162 chr13:91350912    A/G rs1170543143 chr13:91350916    T/C rs1388542964 chr13:91350918    G/C rs1403138754 chr13:91350923    A/C rs1442807536 chr13:91350921    C/G rs764765453 chr13:91350924    CAAG/C rs1051963210 chr13:91350909    T/C rs756288295 chr13:91350905    G/A rs780315531 chr13:91350911    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MAX	chr14:65503099(-) A-I      intronic chr14:65503103(-) A-I      intronic chr14:65503122(-) A-I      intronic chr14:65526624(-) A-I      intronic chr14:65526598(-) A-I      intronic chr14:65525856(-) A-I      intronic chr14:65503123(-) A-I      intronic chr14:65524038(-) A-I      intronic chr14:65521025(-) A-I      intronic chr14:65520995(-) A-I      intronic chr14:65520923(-) A-I      intronic chr14:65518125(-) A-I      intronic chr14:65518117(-) A-I      intronic chr14:65518083(-) A-I      intronic chr14:65518049(-) A-I      intronic chr14:65517146(-) A-I      intronic chr14:65517139(-) A-I      intronic chr14:65503124(-) A-I      intronic chr14:65504067(-) A-I      intronic chr14:65504088(-) A-I      intronic chr14:65504093(-) A-I      intronic chr14:65504699(-) A-I      intronic chr14:65526730(-) A-I      intronic chr14:65526604(-) A-I      intronic chr14:65526727(-) A-I      intronic chr14:65526720(-) A-I      intronic chr14:65526716(-) A-I      intronic chr14:65526690(-) A-I      intronic chr14:65526711(-) A-I      intronic chr14:65526673(-) A-I      intronic chr14:65518785(-) A-I      intronic chr14:65534452(-) A-I      intronic chr14:65504123(-) A-I      intronic chr14:65517126(-) A-I      intronic chr14:65526708(-) A-I      intronic chr14:65534409(-) A-I      intronic chr14:65481383(-) A-I      intronic chr14:65481404(-) A-I      intronic chr14:65481410(-) A-I      intronic chr14:65481432(-) A-I      intronic chr14:65481437(-) A-I      intronic chr14:65514784(-) A-I      intronic chr14:65506906(-) A-I      intronic chr14:65506898(-) A-I      intronic chr14:65506897(-) A-I      intronic chr14:65506895(-) A-I      intronic chr14:65504755(-) A-I      intronic chr14:65504750(-) A-I      intronic chr14:65504729(-) A-I      intronic chr14:65481446(-) A-I      intronic chr14:65503047(-) A-I      intronic chr14:65503051(-) A-I      intronic chr14:65503057(-) A-I      intronic chr14:65503066(-) A-I      intronic chr14:65503069(-) A-I      intronic chr14:65503075(-) A-I      intronic chr14:65503076(-) A-I      intronic chr14:65503083(-) A-I      intronic chr14:65521032(-) A-I      intronic chr14:65521012(-) A-I      intronic chr14:65521006(-) A-I      intronic chr14:65520999(-) A-I      intronic chr14:65520968(-) A-I      intronic chr14:65520963(-) A-I      intronic chr14:65520945(-) A-I      intronic chr14:65520933(-) A-I      intronic chr14:65525838(-) A-I      intronic chr14:65520922(-) A-I      intronic chr14:65520899(-) A-I      intronic chr14:65530359(-) A-I      intronic chr14:65525879(-) A-I      intronic chr14:65527085(-) A-I      intronic chr14:65502770(-) A-I      intronic chr14:65518315(-) A-I      intronic chr14:65518303(-) A-I      intronic chr14:65518217(-) A-I      intronic chr14:65518172(-) A-I      intronic chr14:65518166(-) A-I      intronic chr14:65505373(-) A-I      intronic chr14:65527063(-) A-I      intronic chr14:65518149(-) A-I      intronic chr14:65518071(-) A-I      intronic chr14:65517300(-) A-I      intronic chr14:65527062(-) A-I      intronic chr14:65517257(-) A-I      intronic chr14:65517246(-) A-I      intronic chr14:65527034(-) A-I      intronic chr14:65526770(-) A-I      intronic chr14:65502793(-) A-I      intronic chr14:65517227(-) A-I      intronic chr14:65517226(-) A-I      intronic chr14:65526746(-) A-I      intronic chr14:65526745(-) A-I      intronic chr14:65526725(-) A-I      intronic chr14:65502797(-) A-I      intronic chr14:65526689(-) A-I      intronic chr14:65526680(-) A-I      intronic chr14:65526666(-) A-I      intronic chr14:65502830(-) A-I      intronic chr14:65526648(-) A-I      intronic chr14:65526641(-) A-I      intronic chr14:65502782(-) A-I      intronic chr14:65526628(-) A-I      intronic chr14:65526619(-) A-I      intronic chr14:65524060(-) A-I      intronic chr14:65526590(-) A-I      intronic chr14:65524052(-) A-I      intronic chr14:65522512(-) A-I      intronic chr14:65522507(-) A-I      intronic chr14:65522481(-) A-I      intronic chr14:65522408(-) A-I      intronic chr14:65522405(-) A-I      intronic chr14:65522373(-) A-I      intronic chr14:65526005(-) A-I      intronic chr14:65522372(-) A-I      intronic chr14:65522346(-) A-I      intronic chr14:65505306(-) A-I      intronic chr14:65505353(-) A-I      intronic chr14:65527102(-) A-I      intronic chr14:65525973(-) A-I      intronic chr14:65525967(-) A-I      intronic chr14:65525960(-) A-I      intronic chr14:65525937(-) A-I      intronic chr14:65525885(-) A-I      intronic chr14:65525869(-) A-I      intronic chr14:65525753(-) A-I      intronic chr14:65525752(-) A-I      intronic chr14:65517233(-) A-I      intronic chr14:65524037(-) A-I      intronic chr14:65526019(-) A-I      intronic chr14:65545060(-) A-I      intronic chr14:65524025(-) A-I      intronic chr14:65524015(-) A-I      intronic chr14:65517222(-) A-I      intronic chr14:65522530(-) A-I      intronic chr14:65534498(-) A-I      intronic chr14:65522516(-) A-I      intronic chr14:65533867(-) A-I      intronic chr14:65527090(-) A-I      intronic chr14:65533859(-) A-I      intronic chr14:65533517(-) A-I      intronic chr14:65525844(-) A-I      intronic chr14:65517137(-) A-I      intronic chr14:65522340(-) A-I      intronic chr14:65545084(-) A-I      intronic chr14:65533856(-) A-I      intronic chr14:65533809(-) A-I      intronic chr14:65522331(-) A-I      intronic chr14:65533804(-) A-I      intronic chr14:65521107(-) A-I      intronic chr14:65533691(-) A-I      intronic chr14:65533689(-) A-I      intronic chr14:65521101(-) A-I      intronic chr14:65517116(-) A-I      intronic chr14:65533528(-) A-I      intronic chr14:65533518(-) A-I      intronic chr14:65521056(-) A-I      intronic chr14:65517112(-) A-I      intronic chr14:65533410(-) A-I      intronic chr14:65530562(-) A-I      intronic chr14:65521048(-) A-I      intronic chr14:65530471(-) A-I      intronic chr14:65521046(-) A-I      intronic chr14:65530452(-) A-I      intronic chr14:65517063(-) A-I      intronic chr14:65530447(-) A-I      intronic chr14:65517104(-) A-I      intronic chr14:65521041(-) A-I      intronic chr14:65517069(-) A-I      intronic chr14:65524118(-) A-I      intronic chr14:65524109(-) A-I      intronic chr14:65517057(-) A-I      intronic chr14:65517041(-) A-I      intronic chr14:65515823(-) A-I      intronic chr14:65515819(-) A-I      intronic chr14:65524085(-) A-I      intronic chr14:65515807(-) A-I      intronic chr14:65515806(-) A-I      intronic chr14:65515793(-) A-I      intronic chr14:65515733(-) A-I      intronic chr14:65515619(-) A-I      intronic chr14:65515615(-) A-I      intronic chr14:65514973(-) A-I      intronic chr14:65514910(-) A-I      intronic chr14:65514900(-) A-I      intronic chr14:65514869(-) A-I      intronic chr14:65514838(-) A-I      intronic chr14:65514837(-) A-I      intronic chr14:65514832(-) A-I      intronic chr14:65544987(-) A-I      intronic chr14:65524065(-) A-I      intronic chr14:65514810(-) A-I      intronic chr14:65514773(-) A-I      intronic chr14:65524064(-) A-I      intronic chr14:65514766(-) A-I      intronic chr14:65514743(-) A-I      intronic chr14:65507296(-) A-I      intronic chr14:65507269(-) A-I      intronic chr14:65507266(-) A-I      intronic chr14:65507251(-) A-I      intronic chr14:65505430(-) A-I      intronic chr14:65505400(-) A-I      intronic chr14:65505390(-) A-I      intronic chr14:65524031(-) A-I      intronic chr14:65545095(-) A-I      intronic chr14:65549320(-) A-I      intronic chr14:65534584(-) A-I      intronic chr14:65517187(-) A-I      intronic chr14:65534417(-) A-I      intronic chr14:65534464(-) A-I      intronic chr14:65535053(-) A-I      intronic chr14:65527539(-) A-I      intronic chr14:65534438(-) A-I      intronic chr14:65545344(-) A-I      intronic chr14:65518207(-) A-I      intronic chr14:65533520(-) A-I      intronic chr14:65534468(-) A-I      intronic chr14:65534504(-) A-I      intronic chr14:65518080(-) A-I      intronic chr14:65526620(-) A-I      intronic chr14:65535041(-) A-I      intronic chr14:65525905(-) A-I      intronic chr14:65545098(-) A-I      intronic chr14:65534460(-) A-I      intronic chr14:65517209(-) A-I      intronic chr14:65533356(-) A-I      intronic chr14:65533456(-) A-I      intronic chr14:65534578(-) A-I      intronic chr14:65533460(-) A-I      intronic chr14:65525857(-) A-I      intronic chr14:65557361(-) A-I      intronic chr14:65489901(-) A-I      intronic chr14:65534583(-) A-I      intronic chr14:65535139(-) A-I      intronic chr14:65524047(-) A-I      intronic chr14:65557402(-) A-I      intronic chr14:65526013(-) A-I      intronic chr14:65535031(-) A-I      intronic chr14:65518137(-) A-I      intronic chr14:65534433(-) A-I      intronic chr14:65525833(-) A-I      intronic chr14:65549337(-) A-I      intronic chr14:65525909(-) A-I      intronic chr14:65533485(-) A-I      intronic chr14:65530411(-) A-I      intronic chr14:65525852(-) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MAX	chr14:65542427-65542428(-) m6A 3'UTR//intron       27773535 chr14:65542597-65542598(-) m6A 3'UTR//intron       24284625//24209618//27773535//27371828 chr14:65542640-65542641(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//27371828//22608085 chr14:65542710-65542711(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//27371828//22608085 chr14:65542756-65542757(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085 chr14:65542771-65542772(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085 chr14:65542889-65542890(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//22608085 chr14:65542905-65542906(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22608085 chr14:65542937-65542938(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22608085 chr14:65542943-65542944(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22608085 chr14:65543034-65543035(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22608085 chr14:65543098-65543099(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//22608085 chr14:65543110-65543111(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//27371828//22608085 chr14:65543165-65543166(-) m6A 3'UTR//intron       24284625//24209618//24981863//28052920//27773535//27371828//22608085 chr14:65543260-65543261(-) m6A 3'UTR//CDS//intron       24284625//24209618//24981863//27773535//27371828 chr14:65543320-65543321(-) m6A 3'UTR//CDS//intron       24284625//24209618//27773535//27371828 chr14:65543339-65543340(-) m6A 3'UTR//CDS//intron       24284625//24209618//27773535//27371828 chr14:65543439-65543440(-) m6A 3'UTR//intron       24284625//24209618//27773535//27371828 chr14:65543453-65543454(-) m6A 3'UTR//intron       24284625//24209618//27773535//27371828 chr14:65543462-65543463(-) m6A 3'UTR//intron       24284625//24209618//27773535//27371828 chr14:65543533-65543534(-) m6A 3'UTR//intron       27371828 chr14:65543972-65543973(-) m6A 3'UTR//exon//intron       - chr14:65544405-65544406(-) m6A 3'UTR//exon//intron       27371828 chr14:65544415-65544416(-) m6A 3'UTR//exon//intron       27371828 chr14:65544437-65544438(-) m6A 3'UTR//exon//intron       27371828 chr14:65544458-65544459(-) m6A 3'UTR//exon//intron       27371828 chr14:65544692-65544693(-) m6A 5'UTR//CDS//exon//intron       24981863//27773535 chr14:65544731-65544732(-) m6A 5'UTR//CDS//exon//intron       24981863//27773535 chr14:65550478-65550479(-) m6A 3'UTR//intron       27773535 chr14:65560453-65560454(-) m6A 5'UTR//CDS//exon//intron       27773535 chr14:65560474-65560475(-) m6A 5'UTR//CDS//exon//intron       27773535 chr14:65560486-65560487(-) m6A 5'UTR//CDS//exon//intron       27773535 chr14:65569035-65569036(-) Gm CDS//exon//intron       - chr14:65569148-65569149(-) m6A 5'UTR//exon//intron       24284625//24981863//27773535//27371828

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-19a-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	MAX	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HeLa-S3 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-19a-5p
Interactor2: MAX

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.