Detail Information

Basic Information:


  VIRBase ID:  

HHID00062971

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-1-3p:           C2orf69:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-16-1-3p C2orf69
miRBase
Accession/Entrez ID		 MIMAT0004489 205327
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-16-1-3p
rs377111580 chr13:50048986    C/T
rs769728617 chr13:50048992    CA/C
rs1460126106 chr13:50049003    C/A
rs1460126106 chr13:50049003    C/T
rs1468155921 chr13:50049001    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR C2orf69
chr2:200785558(+) A-I      intronic
chr2:200785859(+) A-I      intronic
chr2:200817807(+) A-I      intronic
chr2:200785532(+) A-I      intronic
chr2:200791372(+) A-I      3'UTR
chr2:200791267(+) A-I      3'UTR
chr2:200788952(+) A-I      intronic
chr2:200788944(+) A-I      intronic
chr2:200777635(+) A-I      intronic
chr2:200786948(+) A-I      intronic
chr2:200789063(+) A-I      intronic
chr2:200789050(+) A-I      intronic
chr2:200791258(+) A-I      3'UTR
chr2:200789019(+) A-I      intronic
chr2:200785869(+) A-I      intronic
chr2:200777640(+) A-I      intronic
chr2:200788999(+) A-I      intronic
chr2:200785416(+) A-I      intronic
chr2:200785991(+) A-I      intronic
chr2:200785402(+) A-I      intronic
chr2:200786855(+) A-I      intronic
chr2:200789081(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED C2orf69
chr2:200785402(+) A-G intron -    22484847
chr2:200785416(+) A-G intron -    22484847
chr2:200785869(+) A-G intron -    22484847
chr2:200791266(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase C2orf69
chr2:200776139-200776140(+) m6A 5'UTR//exon       -
chr2:200776254-200776255(+) m6A CDS//exon       -
chr2:200776261-200776262(+) m6A CDS//exon       -
chr2:200789833-200789834(+) m6A CDS//intron       24284625//22608085
chr2:200789978-200789979(+) m6A CDS//intron       24284625//24209618//24981863//22575960//22608085
chr2:200790088-200790089(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr2:200790159-200790160(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr2:200790298-200790299(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr2:200790304-200790305(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr2:200790333-200790334(+) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr2:200790417-200790418(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr2:200790629-200790630(+) m6A 3'UTR//intron       24981863//22608085
chr2:200790646-200790647(+) m6A 3'UTR//intron       22608085
chr2:200820138-200820139(+) m6A exon       24981863
chr2:200820228-200820229(+) m6A exon       24981863//27371828
chr2:200820269-200820270(+) m6A exon       25456834//24981863//27371828
chr2:200820306-200820307(+) m6A exon       25456834//24981863//27371828//27773536
chr2:200820596-200820597(+) m6A exon       24284625//24981863//22575960

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-16-1-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
C2orf69
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-16-1-3p
Interactor2: C2orf69

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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