Basic Information:

  VIRBase ID:  

HHID00062899

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-1-3p:  MIMAT0004489          ABCF3:  NM_001351299     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-16-1-3p	ABCF3
miRBase Accession/Entrez ID	MIMAT0004489	55324
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	EST201864

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-16-1-3p	rs377111580 chr13:50048986    C/T rs769728617 chr13:50048992    CA/C rs1460126106 chr13:50049003    C/A rs1460126106 chr13:50049003    C/T rs1468155921 chr13:50049001    T/C

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ABCF3	chr3:183903993-183903994(+) m6A 5'UTR//exon       24981863 chr3:183904045-183904046(+) m6A CDS//exon       24981863 chr3:183904318-183904319(+) m6A CDS//exon       24981863//22575960 chr3:183904358-183904359(+) m6A CDS//exon       22575960 chr3:183904381-183904382(+) m6A CDS//exon       - chr3:183904657-183904658(+) m6A CDS//exon       27773535 chr3:183904684-183904685(+) m6A exon//intron       27773535 chr3:183905184-183905185(+) m6A 3'UTR//CDS//exon       - chr3:183905192-183905193(+) m6A 3'UTR//CDS//exon       - chr3:183905197-183905198(+) m6A 3'UTR//CDS//exon       - chr3:183905206-183905207(+) m6A 3'UTR//CDS//exon       - chr3:183905221-183905222(+) m6A 3'UTR//CDS//exon       - chr3:183905443-183905444(+) m6A exon//intron       24981863 chr3:183905451-183905452(+) m6A 3'UTR//CDS//exon       24981863 chr3:183905524-183905525(+) m6A 3'UTR//CDS//exon       24981863 chr3:183905535-183905536(+) m6A 3'UTR//CDS//exon       24981863 chr3:183905599-183905600(+) m6A exon//intron       24981863 chr3:183905719-183905720(+) m6A 3'UTR//CDS//exon       24209618//24981863 chr3:183905746-183905747(+) m6A CDS//exon       24209618 chr3:183905954-183905955(+) m6A CDS//exon       24209618 chr3:183906007-183906008(+) m6A CDS//exon       22575960 chr3:183907298-183907299(+) m6A exon//intron       - chr3:183907315-183907316(+) m6A exon//intron       - chr3:183907408-183907409(+) m6A CDS//exon       - chr3:183907453-183907454(+) m6A CDS//exon       - chr3:183907461-183907462(+) m6A CDS//exon       - chr3:183910944-183910945(+) m6A CDS//exon       24284625 chr3:183911081-183911082(+) m6A exon//intron       24284625 chr3:183911176-183911177(+) m6A CDS//exon       24284625 chr3:183911184-183911185(+) m6A CDS//exon       24284625 chr3:183911193-183911194(+) m6A CDS//exon       24284625 chr3:183911201-183911202(+) m6A CDS//exon       24284625 chr3:183911458-183911459(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr3:183911502-183911503(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr3:183911513-183911514(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr3:183911519-183911520(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr3:183911532-183911533(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr3:183911572-183911573(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr3:183911590-183911591(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr3:183911674-183911675(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr3:183911751-183911752(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-16-1-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	ABCF3	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-16-1-3p
Interactor2: ABCF3

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.