Detail Information

Basic Information:


  VIRBase ID:  

HHID00062744

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-16-1-3p:           IL2RB:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-16-1-3p IL2RB
miRBase
Accession/Entrez ID		 MIMAT0004489 3560
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CD122//IL15RB//IMD63//P70-75

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-16-1-3p
rs377111580 chr13:50048986    C/T
rs769728617 chr13:50048992    CA/C
rs1460126106 chr13:50049003    C/A
rs1460126106 chr13:50049003    C/T
rs1468155921 chr13:50049001    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR IL2RB
chr22:37527914(-) A-I      intronic
chr22:37534094(-) A-I      intronic
chr22:37528046(-) A-I      intronic
chr22:37527915(-) A-I      intronic
chr22:37527837(-) A-I      intronic
chr22:37526950(-) A-I      intronic
chr22:37527144(-) A-I      intronic
chr22:37527082(-) A-I      intronic
chr22:37527125(-) A-I      intronic
chr22:37527955(-) A-I      intronic
chr22:37527176(-) A-I      intronic
chr22:37527024(-) A-I      intronic
chr22:37527954(-) A-I      intronic
chr22:37527873(-) A-I      intronic
chr22:37527098(-) A-I      intronic
chr22:37527095(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED IL2RB
chr22:37527098(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase IL2RB
chr22:37522465-37522466(-) m6A 3'UTR       28052920
chr22:37522501-37522502(-) m6A 3'UTR       28052920
chr22:37523654-37523655(-) m6A 3'UTR       28052920
chr22:37523688-37523689(-) m6A 3'UTR       28052920
chr22:37524619-37524620(-) m6A CDS//exon       -
chr22:37539596-37539597(-) m6A CDS//exon       27371828
chr22:37545904-37545905(-) m6A 5'UTR//intron       27371828
chr22:37557862-37557863(-) m6A 5'UTR//intron       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-16-1-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
IL2RB
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-16-1-3p
Interactor2: IL2RB

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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