Basic Information:

  VIRBase ID:  

HHID00062671

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-let-7f-2-3p:  MIMAT0004487          COL27A1:  NM_032888     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-let-7f-2-3p	COL27A1
miRBase Accession/Entrez ID	MIMAT0004487	85301
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	STLS

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-let-7f-2-3p	rs1556935827 chrX:53557203    C/G rs1556935837 chrX:53557205    G/A rs782106021 chrX:53557206    T/C rs781874809 chrX:53557216    A/G rs782760005 chrX:53557211    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	COL27A1	chr9:117042743(+) A-I      intronic chr9:117042744(+) A-I      intronic chr9:117064886(+) A-I      intronic chr9:117064895(+) A-I      intronic chr9:117064909(+) A-I      intronic chr9:117016225(+) A-I      intronic chr9:117042576(+) A-I      intronic chr9:117042583(+) A-I      intronic chr9:117064812(+) A-I      intronic chr9:117064938(+) A-I      intronic chr9:117041863(+) A-I      intronic chr9:117016190(+) A-I      intronic chr9:117016212(+) A-I      intronic chr9:117016243(+) A-I      intronic chr9:117016252(+) A-I      intronic chr9:117016265(+) A-I      intronic chr9:117016283(+) A-I      intronic chr9:117041910(+) A-I      intronic chr9:117041911(+) A-I      intronic chr9:117041912(+) A-I      intronic chr9:117042735(+) A-I      intronic chr9:117064879(+) A-I      intronic chr9:117064751(+) A-I      intronic chr9:116942394(+) A-I      intronic chr9:117015358(+) A-I      intronic chr9:117015363(+) A-I      intronic chr9:117015425(+) A-I      intronic chr9:117064752(+) A-I      intronic chr9:117015419(+) A-I      intronic chr9:116933883(+) A-I      intronic chr9:117065728(+) A-I      intronic chr9:116942380(+) A-I      intronic chr9:116933929(+) A-I      intronic chr9:116922642(+) A-I      intronic chr9:117041877(+) A-I      intronic chr9:116933861(+) A-I      intronic chr9:117015433(+) A-I      intronic chr9:117016226(+) A-I      intronic chr9:117015472(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	COL27A1	chr9:117010191(+) A-I intron -    21960545

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	COL27A1	chr9:116930397-116930398(+) m6A CDS       24981863//22575960 chr9:116930442-116930443(+) m6A CDS       25456834//24981863//22575960 chr9:116930545-116930546(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr9:116930575-116930576(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr9:116930592-116930593(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr9:116930602-116930603(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr9:116930646-116930647(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr9:116930695-116930696(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr9:116930705-116930706(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr9:116930741-116930742(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr9:116930754-116930755(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr9:116930792-116930793(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr9:116931005-116931006(+) m6A CDS       24209618//24981863 chr9:116931120-116931121(+) m6A CDS       24284625//24209618//25456834//24981863 chr9:116931190-116931191(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr9:116931212-116931213(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr9:116931274-116931275(+) m6A CDS       24284625//24209618//24981863 chr9:116931389-116931390(+) m6A CDS       24209618//24981863 chr9:116931472-116931473(+) m6A CDS       24209618//25456834//24981863 chr9:116931508-116931509(+) m6A CDS       24209618//25456834//24981863 chr9:116931568-116931569(+) m6A CDS       24209618//25456834//24981863 chr9:116931590-116931591(+) m6A CDS       24209618//24981863 chr9:116958276-116958277(+) m6A CDS       - chr9:116967383-116967384(+) m6A CDS//intron       - chr9:116967401-116967402(+) m6A CDS//intron       - chr9:116967422-116967423(+) m6A CDS//intron       - chr9:116968049-116968050(+) m6A CDS//intron       - chr9:116968542-116968543(+) m6A CDS       - chr9:116984507-116984508(+) m6A CDS       - chr9:116993396-116993397(+) m6A CDS       - chr9:116994103-116994104(+) m6A CDS       - chr9:116994130-116994131(+) m6A CDS       - chr9:116997883-116997884(+) m6A 3'UTR//CDS       - chr9:116997927-116997928(+) m6A 3'UTR//CDS       - chr9:117004477-117004478(+) m6A 3'UTR//CDS//exon       - chr9:117027751-117027752(+) m6A 3'UTR//CDS       - chr9:117031498-117031499(+) m6A exon//intron       - chr9:117031531-117031532(+) m6A 3'UTR//CDS//exon       25456834 chr9:117033045-117033046(+) m6A 3'UTR//CDS//exon       25456834 chr9:117033091-117033092(+) m6A exon//intron       - chr9:117036433-117036434(+) m6A exon//intron       - chr9:117037944-117037945(+) m6A 3'UTR//CDS       25456834 chr9:117037953-117037954(+) m6A 3'UTR//CDS       25456834 chr9:117037972-117037973(+) m6A 3'UTR//CDS       25456834 chr9:117044756-117044757(+) m6A 3'UTR//CDS       24209618//25456834//24981863 chr9:117044785-117044786(+) m6A 3'UTR//CDS       24209618//24981863 chr9:117044792-117044793(+) m6A 3'UTR//CDS       24209618//24981863 chr9:117044837-117044838(+) m6A 3'UTR//CDS       24209618//24981863 chr9:117046020-117046021(+) m6A 3'UTR//CDS       24981863 chr9:117046026-117046027(+) m6A 3'UTR//CDS       24981863 chr9:117047005-117047006(+) m6A 3'UTR//CDS       24981863 chr9:117047023-117047024(+) m6A 3'UTR//CDS       24981863 chr9:117047032-117047033(+) m6A 3'UTR//CDS       24209618//24981863 chr9:117047041-117047042(+) m6A 3'UTR//CDS       24209618//24981863 chr9:117051003-117051004(+) m6A 3'UTR//CDS       24209618//25456834//24981863 chr9:117051013-117051014(+) m6A 3'UTR//CDS       24209618//25456834//24981863 chr9:117051021-117051022(+) m6A 3'UTR//CDS       24209618//25456834//24981863 chr9:117051195-117051196(+) m6A 3'UTR//CDS       24209618//25456834//24981863 chr9:117051532-117051533(+) m6A 3'UTR//CDS       25456834//27773536 chr9:117051550-117051551(+) m6A 3'UTR//CDS       25456834//24981863//27773536 chr9:117052339-117052340(+) m6A 3'UTR//CDS       25456834//24981863//27773536 chr9:117052544-117052545(+) m6A 3'UTR//CDS       24209618//25456834//24981863 chr9:117052568-117052569(+) m6A 3'UTR//CDS       24209618//25456834 chr9:117052604-117052605(+) m6A 3'UTR//CDS       24209618//25456834 chr9:117053111-117053112(+) m6A 3'UTR//CDS       24209618//25456834 chr9:117053181-117053182(+) m6A 3'UTR//CDS       24209618//25456834 chr9:117054402-117054403(+) m6A 3'UTR//CDS       24209618//25456834 chr9:117054430-117054431(+) m6A 3'UTR//CDS       24209618//25456834 chr9:117054458-117054459(+) m6A 3'UTR//CDS       24209618//25456834 chr9:117062396-117062397(+) m6A 3'UTR//CDS       24209618 chr9:117068743-117068744(+) m6A exon//intron       - chr9:117068755-117068756(+) m6A exon//intron       - chr9:117068761-117068762(+) m6A exon//intron       - chr9:117068815-117068816(+) m6A 3'UTR//CDS//exon       - chr9:117068830-117068831(+) m6A 3'UTR//CDS//exon       - chr9:117068853-117068854(+) m6A 3'UTR//CDS//exon       - chr9:117071659-117071660(+) m6A 3'UTR//CDS//exon       - chr9:117071700-117071701(+) m6A 3'UTR//CDS//exon       - chr9:117072956-117072957(+) m6A 3'UTR//CDS//exon       25456834 chr9:117073097-117073098(+) m6A 3'UTR//exon       - chr9:117073161-117073162(+) m6A 3'UTR//exon       - chr9:117073188-117073189(+) m6A 3'UTR//exon       - chr9:117073219-117073220(+) m6A 3'UTR//exon       - chr9:117073385-117073386(+) m6A 3'UTR//exon       24981863//27773535 chr9:117073410-117073411(+) m6A 3'UTR//exon       24981863//27773535 chr9:117073437-117073438(+) m6A 3'UTR//exon       24981863//27773535 chr9:117073679-117073680(+) m6A 3'UTR//exon       24981863//27773535 chr9:117073690-117073691(+) m6A 3'UTR//exon       24981863//27773535 chr9:117073850-117073851(+) m6A 3'UTR       24981863//27773535//22608085 chr9:117073856-117073857(+) m6A 3'UTR       24981863//27773535//22608085 chr9:117073862-117073863(+) m6A 3'UTR       24981863//27773535//22608085 chr9:117073868-117073869(+) m6A 3'UTR       24981863//27773535//22608085 chr9:117073880-117073881(+) m6A 3'UTR       24981863//27773535//22608085 chr9:117073915-117073916(+) m6A 3'UTR       24981863//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-let-7f-2-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	COL27A1	Cytosol HCC cell line (HepG2)     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Membrane HCC cell line (HepG2)     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-let-7f-2-3p
Interactor2: COL27A1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.