Detail Information

Basic Information:


  VIRBase ID:  

HHID00062463

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-let-7f-1-3p:           PDE12:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-let-7f-1-3p PDE12
miRBase
Accession/Entrez ID		 MIMAT0004486 201626
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - 2'-PDE//2-PDE

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-let-7f-1-3p
rs1242905594 chr9:94176409    C/T
rs1440850304 chr9:94176429    C/T
rs375140031 chr9:94176420    A/G
rs778240668 chr9:94176418    C/A
rs753257172 chr9:94176416    A/C
rs753257172 chr9:94176416    A/G
rs780673185 chr9:94176411    A/C
rs780673185 chr9:94176411    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PDE12
chr3:57544801(+) A-I      intronic
chr3:57546192(+) A-I      3'UTR
chr3:57546182(+) A-I      3'UTR
chr3:57546153(+) A-I      3'UTR
chr3:57546152(+) A-I      3'UTR
chr3:57544357(+) A-I      intronic
chr3:57544271(+) A-I      intronic
chr3:57544889(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PDE12
chr3:57544357(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PDE12
chr3:57542193-57542194(+) m6A CDS       24284625
chr3:57542243-57542244(+) m6A CDS       24284625
chr3:57542290-57542291(+) m6A CDS       24284625
chr3:57542603-57542604(+) m6A CDS       24284625//22575960
chr3:57542651-57542652(+) m6A CDS       24284625//22575960//22608085
chr3:57542781-57542782(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr3:57542787-57542788(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr3:57543019-57543020(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr3:57543033-57543034(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr3:57543103-57543104(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr3:57543119-57543120(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr3:57543344-57543345(+) m6A CDS       24284625//24981863//26404942//22608085
chr3:57543356-57543357(+) m6A CDS       24284625//24981863//26404942//22608085
chr3:57545061-57545062(+) m6A CDS       24284625//24981863//22608085
chr3:57545147-57545148(+) m6A 3'UTR//intron       24284625//22608085
chr3:57545207-57545208(+) m6A 3'UTR//intron       24284625//22608085
chr3:57545244-57545245(+) m6A 3'UTR//intron       24284625//24981863//22608085
chr3:57545337-57545338(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22608085
chr3:57545387-57545388(+) m6A 3'UTR//CDS       24284625//24981863//26404942//22608085
chr3:57545459-57545460(+) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//22608085
chr3:57545538-57545539(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22608085
chr3:57545619-57545620(+) m6A 3'UTR//CDS       24284625//24981863//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-let-7f-1-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Extracellular vesicle Colon cancer cell line (LIM1863)     25330373
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
PDE12
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytosol K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Colon cancer cells     24393600
Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-let-7f-1-3p
Interactor2: PDE12

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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