Detail Information

Basic Information:


  VIRBase ID:  

HHID00062364

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-let-7f-1-3p:           ICOSLG:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-let-7f-1-3p ICOSLG
miRBase
Accession/Entrez ID		 MIMAT0004486 23308
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - B7-H2//B7h//B7H2//B7RP-1//B7RP1//CD275//GL50//ICOS-L//ICOSL//LICOS

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-let-7f-1-3p
rs1242905594 chr9:94176409    C/T
rs1440850304 chr9:94176429    C/T
rs375140031 chr9:94176420    A/G
rs778240668 chr9:94176418    C/A
rs753257172 chr9:94176416    A/C
rs753257172 chr9:94176416    A/G
rs780673185 chr9:94176411    A/C
rs780673185 chr9:94176411    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ICOSLG
chr21:45644051(-) A-I      3'UTR
chr21:45644085(-) A-I      3'UTR
chr21:45644139(-) A-I      3'UTR
chr21:45644142(-) A-I      3'UTR
chr21:45644382(-) A-I      3'UTR
chr21:45644419(-) A-I      3'UTR
chr21:45644460(-) A-I      3'UTR
chr21:45644108(-) A-I      3'UTR
chr21:45644503(-) A-I      3'UTR
chr21:45644551(-) A-I      3'UTR
chr21:45643710(-) A-I      3'UTR
chr21:45651992(-) A-I      intronic
chr21:45653325(-) A-I      intronic
chr21:45653282(-) A-I      intronic
chr21:45653274(-) A-I      intronic
chr21:45652437(-) A-I      intronic
chr21:45652196(-) A-I      intronic
chr21:45652123(-) A-I      intronic
chr21:45652832(-) A-I      intronic
chr21:45652733(-) A-I      intronic
chr21:45652726(-) A-I      intronic
chr21:45652526(-) A-I      intronic
chr21:45652455(-) A-I      intronic
chr21:45652113(-) A-I      intronic
chr21:45652107(-) A-I      intronic
chr21:45643682(-) A-I      3'UTR
chr21:45643905(-) A-I      3'UTR
chr21:45643626(-) A-I      3'UTR
chr21:45644022(-) A-I      3'UTR
chr21:45644063(-) A-I      3'UTR
chr21:45644365(-) A-I      3'UTR
chr21:45643969(-) A-I      3'UTR
chr21:45644395(-) A-I      3'UTR
chr21:45644465(-) A-I      3'UTR
chr21:45643629(-) A-I      3'UTR
chr21:45643684(-) A-I      3'UTR
chr21:45644535(-) A-I      3'UTR
chr21:45644067(-) A-I      3'UTR
chr21:45644565(-) A-I      3'UTR
chr21:45643999(-) A-I      3'UTR
chr21:45643991(-) A-I      3'UTR
chr21:45644077(-) A-I      3'UTR
chr21:45643945(-) A-I      3'UTR
chr21:45643940(-) A-I      3'UTR
chr21:45643696(-) A-I      3'UTR
chr21:45643937(-) A-I      3'UTR
chr21:45644004(-) A-I      3'UTR
chr21:45643966(-) A-I      3'UTR
chr21:45643933(-) A-I      3'UTR
chr21:45644172(-) A-I      3'UTR
chr21:45643950(-) A-I      3'UTR
chr21:45643990(-) A-I      3'UTR
chr21:45643979(-) A-I      3'UTR
chr21:45643794(-) A-I      3'UTR
chr21:45644186(-) A-I      3'UTR
chr21:45644312(-) A-I      3'UTR
chr21:45644014(-) A-I      3'UTR
chr21:45643878(-) A-I      3'UTR
chr21:45643731(-) A-I      3'UTR
chr21:45643976(-) A-I      3'UTR
chr21:45643704(-) A-I      3'UTR
chr21:45643705(-) A-I      3'UTR
chr21:45644357(-) A-I      3'UTR
chr21:45652772(-) A-I      intronic
chr21:45653320(-) A-I      intronic
chr21:45653351(-) A-I      intronic
chr21:45651763(-) A-I      intronic
chr21:45652877(-) A-I      intronic
chr21:45652743(-) A-I      intronic
chr21:45653414(-) A-I      intronic
chr21:45652540(-) A-I      intronic
chr21:45652823(-) A-I      intronic
chr21:45653390(-) A-I      intronic
chr21:45653337(-) A-I      intronic
chr21:45652638(-) A-I      intronic
chr21:45644045(-) A-I      3'UTR
chr21:45643888(-) A-I      3'UTR
chr21:45644435(-) A-I      3'UTR
chr21:45643901(-) A-I      3'UTR
chr21:45644125(-) A-I      3'UTR
chr21:45644562(-) A-I      3'UTR
chr21:45644342(-) A-I      3'UTR
chr21:45644519(-) A-I      3'UTR
chr21:45643695(-) A-I      3'UTR
chr21:45643747(-) A-I      3'UTR
chr21:45644330(-) A-I      3'UTR
chr21:45644321(-) A-I      3'UTR
chr21:45644446(-) A-I      3'UTR
chr21:45644383(-) A-I      3'UTR
chr21:45644440(-) A-I      3'UTR
chr21:45643736(-) A-I      3'UTR
chr21:45644370(-) A-I      3'UTR
chr21:45644053(-) A-I      3'UTR
chr21:45643763(-) A-I      3'UTR
chr21:45644177(-) A-I      3'UTR
chr21:45644164(-) A-I      3'UTR
chr21:45644028(-) A-I      3'UTR
chr21:45644100(-) A-I      3'UTR
chr21:45643965(-) A-I      3'UTR
chr21:45644384(-) A-I      3'UTR
chr21:45644343(-) A-I      3'UTR
chr21:45644518(-) A-I      3'UTR
chr21:45644498(-) A-I      3'UTR
chr21:45644421(-) A-I      3'UTR
chr21:45643910(-) A-I      3'UTR
chr21:45644571(-) A-I      3'UTR
chr21:45643911(-) A-I      3'UTR
chr21:45644472(-) A-I      3'UTR
chr21:45644369(-) A-I      3'UTR
chr21:45643869(-) A-I      3'UTR
chr21:45644075(-) A-I      3'UTR
chr21:45644484(-) A-I      3'UTR
chr21:45653265(-) A-I      intronic
chr21:45656070(-) A-I      intronic
chr21:45653427(-) A-I      intronic
chr21:45652064(-) A-I      intronic
chr21:45652070(-) A-I      intronic
chr21:45652429(-) A-I      intronic
chr21:45653299(-) A-I      intronic
chr21:45652742(-) A-I      intronic
chr21:45653392(-) A-I      intronic
chr21:45652169(-) A-I      intronic
chr21:45652556(-) A-I      intronic
chr21:45652882(-) A-I      intronic
chr21:45652828(-) A-I      intronic
chr21:45652175(-) A-I      intronic
chr21:45652813(-) A-I      intronic
chr21:45652353(-) A-I      intronic
chr21:45652351(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ICOSLG
chr21:45653320(-) A-I intron -    22327324
chr21:45652877(-) A-T intron -    22484847
chr21:45652882(-) A-G intron -    22484847
chr21:45653265(-) A-G intron -    22484847
chr21:45653320(-) A-G intron -    22484847
chr21:45653337(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ICOSLG
chr21:45642896-45642897(-) m6A 3'UTR       25456834//24981863
chr21:45642951-45642952(-) m6A 3'UTR//CDS       25456834//24981863
chr21:45642976-45642977(-) m6A 3'UTR//intron       25456834//24981863
chr21:45643002-45643003(-) m6A 3'UTR//intron       24284625//25456834//24981863
chr21:45643036-45643037(-) m6A 3'UTR//intron       24284625//25456834//24981863
chr21:45643233-45643234(-) m6A 3'UTR//intron       -
chr21:45643270-45643271(-) m6A 3'UTR//intron       -
chr21:45644776-45644777(-) m6A 3'UTR//intron       24284625
chr21:45644846-45644847(-) m6A 3'UTR//intron       24284625
chr21:45644903-45644904(-) m6A 3'UTR//intron       24284625
chr21:45644914-45644915(-) m6A 3'UTR//intron       24284625
chr21:45644954-45644955(-) m6A 3'UTR//intron       24284625
chr21:45645070-45645071(-) m6A 3'UTR//intron       24284625
chr21:45645167-45645168(-) m6A 3'UTR//intron       24284625
chr21:45645665-45645666(-) m6A 3'UTR//intron       24284625//27773535
chr21:45645748-45645749(-) m6A 3'UTR//intron       24284625//25456834
chr21:45645837-45645838(-) m6A 3'UTR//intron       24284625//25456834
chr21:45645875-45645876(-) m6A 3'UTR//intron       24284625//25456834
chr21:45645959-45645960(-) m6A 3'UTR//intron       24284625//25456834
chr21:45646080-45646081(-) m6A 3'UTR//intron       24284625//24209618//25456834
chr21:45646276-45646277(-) m6A 3'UTR//intron       24284625//25456834//28052920//27371828//27773536
chr21:45646321-45646322(-) m6A 3'UTR//intron       24284625//25456834//24981863//28052920//27371828//27773536
chr21:45646333-45646334(-) m6A 3'UTR//intron       24284625//25456834//24981863//28052920//27371828//27773536
chr21:45646351-45646352(-) m6A 3'UTR//intron       24284625//25456834//24981863//28052920//27371828//27773536
chr21:45646410-45646411(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27371828//27773536
chr21:45646477-45646478(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27371828//27773536
chr21:45646577-45646578(-) m6A 3'UTR//intron       24284625//24209618//25456834
chr21:45646615-45646616(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863
chr21:45646639-45646640(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863
chr21:45646746-45646747(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920
chr21:45646762-45646763(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863
chr21:45646785-45646786(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863
chr21:45646849-45646850(-) m6A 3'UTR//intron       24284625
chr21:45646980-45646981(-) m6A 3'UTR//intron       24284625//25456834
chr21:45647131-45647132(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr21:45647186-45647187(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr21:45647221-45647222(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr21:45647311-45647312(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr21:45647344-45647345(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr21:45647491-45647492(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//22608085
chr21:45647509-45647510(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//22608085
chr21:45647516-45647517(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr21:45647522-45647523(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr21:45647554-45647555(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr21:45647580-45647581(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr21:45647664-45647665(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr21:45647686-45647687(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr21:45647905-45647906(-) m6A 3'UTR//intron       24284625
chr21:45648138-45648139(-) m6A 3'UTR//intron       24284625//25456834
chr21:45648278-45648279(-) m6A 3'UTR//intron       24284625//28052920
chr21:45648383-45648384(-) m6A 3'UTR//intron       24284625//25456834//28052920//27371828
chr21:45648448-45648449(-) m6A 3'UTR//intron       24284625//25456834//28052920//27371828
chr21:45648514-45648515(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27371828
chr21:45648542-45648543(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27371828//22608085
chr21:45648581-45648582(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27371828//22608085
chr21:45648648-45648649(-) m6A 3'UTR//intron       24284625//24209618//25456834//28052920//27371828//22575960
chr21:45648770-45648771(-) m6A 3'UTR//intron       24284625//25456834//24981863//28052920//27371828//27773536//22575960//22608085
chr21:45648793-45648794(-) m6A 3'UTR//intron       24284625//25456834//24981863//28052920//27371828//27773536//22575960//22608085
chr21:45648828-45648829(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085
chr21:45648836-45648837(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085
chr21:45648890-45648891(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085
chr21:45648995-45648996(-) m6A 3'UTR//intron       24284625//27371828
chr21:45649029-45649030(-) m6A 3'UTR//intron       24284625
chr21:45649099-45649100(-) m6A 3'UTR//intron       24284625//25456834
chr21:45649115-45649116(-) m6A 3'UTR//intron       24284625//25456834
chr21:45649188-45649189(-) m6A 3'UTR//intron       24284625//25456834//27371828
chr21:45649238-45649239(-) m6A 3'UTR//intron       24284625//25456834//27371828
chr21:45649823-45649824(-) m6A CDS//intron       25456834
chr21:45649948-45649949(-) m6A CDS       -
chr21:45651188-45651189(-) m6A CDS       -
chr21:45655157-45655158(-) m6A CDS       24284625
chr21:45655177-45655178(-) m6A CDS       24284625
chr21:45655216-45655217(-) m6A CDS       24284625
chr21:45655229-45655230(-) m6A CDS       24284625
chr21:45655276-45655277(-) m6A CDS       24284625
chr21:45655309-45655310(-) m6A CDS       24284625
chr21:45655324-45655325(-) m6A CDS       24284625
chr21:45655441-45655442(-) m6A CDS       24284625
chr21:45656910-45656911(-) m6A CDS//intron       24284625
chr21:45656925-45656926(-) m6A CDS//intron       24284625
chr21:45656946-45656947(-) m6A CDS//intron       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-let-7f-1-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Extracellular vesicle Colon cancer cell line (LIM1863)     25330373
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
ICOSLG
Exosome Blood     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-let-7f-1-3p
Interactor2: ICOSLG

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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